Detailed information NTG0262086

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: LLG50_RS02565
• Genome accession: NZ_CP025500
• Coordinates: 502869..505115 (+)
• Length: 748 a.a.
• NCBI ID: WP_103054484.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain G50
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 497869..510115

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLG50_RS02545 (LLG50_02545)	rpoD	498464..499807 (+)	1344	WP_003130829.1	RNA polymerase sigma factor RpoD	-
LLG50_RS02550 (LLG50_02550)	-	499921..500664 (+)	744	WP_010905438.1	MurR/RpiR family transcriptional regulator	-
LLG50_RS02555 (LLG50_02555)	-	500829..502196 (+)	1368	WP_201261407.1	MFS transporter	-
LLG50_RS02560 (LLG50_02560)	-	502480..502818 (+)	339	WP_103054483.1	hypothetical protein	-
LLG50_RS02565 (LLG50_02565)	clpC	502869..505115 (+)	2247	WP_103054484.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
LLG50_RS02570 (LLG50_02570)	-	505219..505485 (-)	267	WP_103054485.1	hypothetical protein	-
LLG50_RS02575 (LLG50_02575)	-	505522..505992 (-)	471	WP_003130820.1	Rrf2 family transcriptional regulator	-
LLG50_RS02580 (LLG50_02580)	gap	506165..507178 (+)	1014	WP_003130818.1	type I glyceraldehyde-3-phosphate dehydrogenase	-
LLG50_RS02585 (LLG50_02585)	def	507321..507956 (-)	636	WP_003130816.1	peptide deformylase	-
LLG50_RS02590 (LLG50_02590)	-	508104..508565 (+)	462	WP_306171264.1	RNA pyrophosphohydrolase	-

Sequence

Protein

• Length: 748 a.a.
• Molecular weight: 83141.95 Da
• Isoelectric Point: 4.8126

>NTDB_id=262086 LLG50_RS02565 WP_103054484.1 502869..505115(+) (clpC) [Lactococcus lactis subsp. lactis strain G50]
MLCQNCNINEATIHLYTSVNGQKKQIDLCQNCYQIMKSGGQEALFGAGNASNGNSDEPFNPFNDIFSALHGQDFNGAAST
QTPPTQTGGRGPRGPQNPRVKQPKGMLEEFGINITESARRGEIDPVIGRDEEIKRVIEILNRRTKNNPVLIGEPGVGKTA
VVEGLAQKIVDGDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRKRNDVIMFIDEIHEIVGAGSAGDGNMD
AGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQARYEDYHHVKYTDEAIEAAAH
LSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFVDPEDINRRIADAETKKNEATQAEDFEKAAHFRDQITKLRELQNHEVS
DDEIPVITEKDIEQIVEQKTHIPVGDLKEKEQTQLINLADDLKAHVIGQDEAVDKIAKAIRRSRVGLGKPNRPIGSFLFV
GPTGVGKTELAKQLAKELFGSSESMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHP
DVMHMFLQILEDGRLTDAQGRTVSFKDSLIIMTSNAGTGKVEASVGFGAAREGRTKSVLGQLGDFFSPEFMNRFDGIIEF
SALSKENLLKIVDLMLDEVNEQIGRNDIHLSVTQAAKEKLVDLGYNPAMGARPLRRTIQENIEDSIADFYIEHPEYKELV
ADLIDDKIVISNQAQEAAETTDEKVPAE

Nucleotide

• Length: 2247 bp

>NTDB_id=262086 LLG50_RS02565 WP_103054484.1 502869..505115(+) (clpC) [Lactococcus lactis subsp. lactis strain G50]
ATGCTTTGTCAAAATTGTAATATTAATGAAGCGACGATTCACCTTTACACAAGTGTAAATGGTCAGAAAAAACAAATTGA
TTTGTGCCAAAACTGTTATCAAATTATGAAATCTGGCGGTCAAGAAGCTTTATTTGGCGCAGGAAATGCCTCAAATGGAA
ATTCTGATGAACCATTTAATCCATTTAATGATATCTTCAGTGCTTTGCACGGTCAAGATTTTAATGGAGCAGCAAGCACT
CAAACTCCACCAACACAAACTGGTGGACGTGGTCCGCGCGGTCCACAAAATCCTCGGGTAAAACAACCTAAAGGAATGTT
AGAAGAATTTGGAATTAACATCACAGAGTCAGCTCGTCGTGGCGAAATTGACCCAGTGATTGGGCGTGATGAAGAAATTA
AACGTGTCATTGAGATTTTAAATCGTAGGACTAAGAATAATCCTGTATTAATTGGTGAACCTGGTGTTGGTAAAACAGCA
GTTGTTGAAGGTTTAGCGCAAAAAATTGTGGACGGAGATGTGCCGCAAAAACTACAAAATAAAGAAGTGATTCGTCTTGA
TGTTGTTTCTCTTGTTCAAGGAACAGGAATTCGTGGACAATTTGAAGAACGGATGCAAAAATTAATGGATGAAATCAGAA
AACGTAATGATGTGATTATGTTTATTGATGAAATTCATGAAATTGTTGGTGCTGGTTCTGCCGGTGATGGCAATATGGAT
GCAGGAAATATCCTAAAACCTGCGCTTGCGCGTGGTGAGCTTCAATTGGTCGGAGCAACAACGCTCAATGAATATCGCAT
CATTGAAAAAGATGCTGCGCTTGAACGCCGGATGCAACCAGTTAAAGTCGATGAACCATCAGTTGATGAAACAATTACTA
TTTTGCGAGGCATTCAAGCACGTTATGAAGATTATCATCACGTGAAATACACTGATGAGGCTATTGAAGCAGCCGCTCAT
TTGTCAAATCGTTACATTCAAGACCGTTTCTTACCAGATAAAGCCATTGACCTTTTGGATGAGTCTGGTTCTAAGAAAAA
TCTAACCTTGAAATTTGTTGATCCTGAAGATATTAATCGTCGGATTGCGGATGCAGAAACGAAGAAAAATGAAGCAACAC
AGGCTGAAGATTTTGAAAAAGCCGCTCATTTCCGTGACCAAATCACTAAACTTCGTGAATTACAAAATCATGAAGTTTCA
GATGATGAAATTCCTGTCATCACTGAAAAAGATATTGAACAAATTGTTGAGCAAAAAACACATATTCCAGTTGGTGATTT
GAAAGAAAAAGAACAAACCCAATTGATTAATTTGGCTGATGATTTGAAAGCACATGTGATTGGTCAGGATGAAGCAGTGG
ATAAGATTGCTAAAGCTATCCGTCGTTCTCGTGTGGGACTTGGTAAACCTAATCGTCCAATTGGTTCTTTCCTTTTCGTT
GGTCCAACAGGTGTTGGTAAAACAGAACTTGCTAAACAATTGGCTAAAGAATTATTTGGCTCAAGTGAAAGTATGATTCG
TTTTGACATGTCGGAATACATGGAAAAACATTCGGTGGCCAAATTGATTGGAGCCCCTCCAGGATATGTGGGTTATGAAG
AAGCTGGTCAATTGACTGAACGTGTTCGTCGTAATCCCTACAGTTTGATTTTATTAGATGAAATCGAAAAAGCACATCCA
GATGTGATGCACATGTTCTTGCAAATTCTTGAAGATGGACGTCTGACAGACGCACAAGGACGGACAGTATCCTTTAAAGA
TAGTTTGATTATTATGACTTCTAATGCCGGAACTGGTAAAGTTGAAGCCTCTGTCGGATTTGGTGCTGCTCGTGAGGGAC
GAACTAAATCAGTGCTTGGTCAGCTTGGCGATTTCTTTAGCCCTGAATTCATGAACCGTTTTGACGGAATAATTGAATTC
TCTGCTTTGAGCAAAGAAAATCTCCTTAAAATTGTTGATTTGATGCTTGATGAAGTCAACGAACAAATTGGACGTAATGA
TATTCATCTTAGTGTCACTCAAGCAGCAAAAGAAAAATTAGTTGATCTAGGTTACAATCCAGCAATGGGTGCAAGACCAC
TTCGTAGAACAATTCAAGAAAATATCGAAGATTCAATTGCTGACTTCTATATTGAGCACCCTGAATACAAAGAATTGGTT
GCTGATTTGATTGATGATAAAATTGTTATCTCTAATCAAGCTCAAGAAGCAGCAGAAACGACTGATGAAAAAGTTCCTGC
TGAATAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (149-268)

• AAA lid domain (AAA_lid_9) (287-386)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (643-713)

• AAA domain (Cdc48 subfamily) (AAA_2) (472-635)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	97.594	100	0.976
clpE	Streptococcus mutans UA159	76.026	100	0.767
clpE	Streptococcus pneumoniae Rx1	73.781	100	0.749
clpE	Streptococcus pneumoniae D39	73.781	100	0.749
clpE	Streptococcus pneumoniae R6	73.781	100	0.749
clpE	Streptococcus pneumoniae TIGR4	73.781	100	0.749
clpC	Bacillus subtilis subsp. subtilis str. 168	52.006	86.631	0.451
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.635	81.952	0.39
clpC	Streptococcus pneumoniae Rx1	46.635	83.422	0.389
clpC	Streptococcus pneumoniae D39	46.635	83.422	0.389
clpC	Streptococcus pneumoniae TIGR4	46.635	83.422	0.389
clpC	Streptococcus thermophilus LMD-9	46.104	82.353	0.38
clpC	Streptococcus thermophilus LMG 18311	45.942	82.353	0.378
clpC	Streptococcus mutans UA159	45.631	82.62	0.377