Detailed information NTG0262022

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: A7U46_RS07475
• Genome accession: NZ_CP025495
• Coordinates: 1475526..1476413 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 3020.C01
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1470526..1481413

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7U46_RS07445 (A7U46_007445)	-	1471258..1472019 (+)	762	WP_000323455.1	alpha/beta hydrolase	-
A7U46_RS07450 (A7U46_007450)	-	1472264..1472719 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
A7U46_RS15635 (A7U46_007455)	-	1472841..1472942 (+)	102	WP_000731972.1	SE2200 family small protein	-
A7U46_RS07460 (A7U46_007460)	-	1473002..1474426 (-)	1425	WP_000953744.1	alkaline phosphatase	-
A7U46_RS07465 (A7U46_007465)	-	1474624..1474824 (+)	201	WP_000604728.1	hypothetical protein	-
A7U46_RS07470 (A7U46_007470)	braR	1474850..1475515 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
A7U46_RS07475 (A7U46_007475)	braS	1475526..1476413 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
A7U46_RS07480 (A7U46_007480)	-	1476521..1477276 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
A7U46_RS07485 (A7U46_007485)	-	1477273..1479273 (+)	2001	WP_000776751.1	ABC transporter permease	-
A7U46_RS07490 (A7U46_007490)	-	1479932..1480045 (+)	114	WP_001791776.1	hypothetical protein	-
A7U46_RS07500 (A7U46_007500)	-	1480427..1480687 (+)	261	WP_001789910.1	hypothetical protein	-
A7U46_RS07505 (A7U46_007505)	-	1480697..1481194 (+)	498	WP_001065268.1	glutathione peroxidase	-
A7U46_RS07510 (A7U46_007510)	-	1481302..1481394 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=262022 A7U46_RS07475 WP_000143419.1 1475526..1476413(+) (braS) [Staphylococcus aureus strain 3020.C01]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=262022 A7U46_RS07475 WP_000143419.1 1475526..1476413(+) (braS) [Staphylococcus aureus strain 3020.C01]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997