Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   CYK58_RS00760 Genome accession   NZ_CP025474
Coordinates   153084..153827 (+) Length   247 a.a.
NCBI ID   WP_000660533.1    Uniprot ID   -
Organism   Helicobacter pylori strain H-137     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 148084..158827
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CYK58_RS00735 (CYK58_00735) panD 150234..150584 (+) 351 WP_126130756.1 aspartate 1-decarboxylase -
  CYK58_RS00740 (CYK58_00740) - 150595..150888 (+) 294 WP_000347916.1 YbaB/EbfC family nucleoid-associated protein -
  CYK58_RS00745 (CYK58_00745) - 150888..151883 (+) 996 WP_126131605.1 PDZ domain-containing protein -
  CYK58_RS00750 (CYK58_00750) comB6 151891..152946 (+) 1056 WP_126131604.1 P-type conjugative transfer protein TrbL Machinery gene
  CYK58_RS00755 (CYK58_00755) comB7 152962..153087 (+) 126 WP_021307643.1 hypothetical protein Machinery gene
  CYK58_RS00760 (CYK58_00760) comB8 153084..153827 (+) 744 WP_000660533.1 virB8 family protein Machinery gene
  CYK58_RS00765 (CYK58_00765) comB9 153827..154792 (+) 966 WP_126130757.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  CYK58_RS00770 (CYK58_00770) comB10 154785..155921 (+) 1137 WP_126130758.1 DNA type IV secretion system protein ComB10 Machinery gene
  CYK58_RS00775 (CYK58_00775) - 155991..157403 (+) 1413 WP_126130759.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  CYK58_RS00780 (CYK58_00780) gmd 157444..158589 (+) 1146 WP_126130760.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28670.89 Da        Isoelectric Point: 8.9546

>NTDB_id=261862 CYK58_RS00760 WP_000660533.1 153084..153827(+) (comB8) [Helicobacter pylori strain H-137]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAVVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=261862 CYK58_RS00760 WP_000660533.1 153084..153827(+) (comB8) [Helicobacter pylori strain H-137]
ATGAAGGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTCAGGTTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGGTTGTTTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCTATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAATCGCATTGACGATAAATCGCGTT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAGGATTTGATCAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCTATTGCGGCTAAACTCATGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTTACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.761

100

0.968

Multiple sequence alignment