Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   CYD28_RS04645 Genome accession   NZ_CP025396
Coordinates   970183..970899 (-) Length   238 a.a.
NCBI ID   WP_011275301.1    Uniprot ID   Q4L7S3
Organism   Staphylococcus haemolyticus strain B     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 965183..975899
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CYD28_RS04625 (CYD28_04625) - 965224..966468 (+) 1245 WP_033079908.1 ammonium transporter -
  CYD28_RS04630 (CYD28_04630) - 966568..967527 (+) 960 WP_033079907.1 LacI family DNA-binding transcriptional regulator -
  CYD28_RS04635 (CYD28_04635) - 967612..969096 (+) 1485 WP_103416033.1 sucrose-6-phosphate hydrolase -
  CYD28_RS04640 (CYD28_04640) - 969100..970065 (+) 966 WP_011275300.1 carbohydrate kinase family protein -
  CYD28_RS04645 (CYD28_04645) agrA 970183..970899 (-) 717 WP_011275301.1 quorum-sensing response regulator AgrA Regulator
  CYD28_RS04650 (CYD28_04650) agrC 970918..972201 (-) 1284 WP_041615113.1 quorum-sensing sensor histidine kinase AgrC -
  CYD28_RS04655 (CYD28_04655) agrD 972233..972370 (-) 138 WP_011275303.1 cyclic lactone autoinducer peptide AgrD -
  CYD28_RS04660 (CYD28_04660) - 972373..972939 (-) 567 WP_011275304.1 accessory gene regulator AgrB -
  CYD28_RS04665 (CYD28_04665) - 973669..974454 (-) 786 WP_011275305.1 carbon-nitrogen family hydrolase -
  CYD28_RS04670 (CYD28_04670) - 974647..975270 (-) 624 WP_011275306.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27801.74 Da        Isoelectric Point: 5.2189

>NTDB_id=260877 CYD28_RS04645 WP_011275301.1 970183..970899(-) (agrA) [Staphylococcus haemolyticus strain B]
MKIFICEDDVKQRENMVSIINNYIMIEEKPMEIALATDDPYEVIEKSKEMNDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPSQLQSRIIDCLETAHTRLKLLSKESTVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVVNRHNIESIDSKERIVNFKNGEHCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=260877 CYD28_RS04645 WP_011275301.1 970183..970899(-) (agrA) [Staphylococcus haemolyticus strain B]
ATGAAAATATTCATTTGTGAAGATGATGTAAAACAACGTGAAAATATGGTTTCAATTATTAATAATTACATTATGATTGA
AGAAAAACCTATGGAGATTGCGCTTGCAACAGACGATCCTTATGAAGTCATTGAAAAATCTAAAGAGATGAATGATGTCG
GATGTTACTTTCTTGATATTCAATTAGAGGCTGATATCAACGGTATTAAATTAGGTAGTGAAATTCGTAAGTATGACCCT
ATTGGAAATATCATATTCGTTACAAGTCATAGTGAGTTAACATACCTAACCTTTGTTTACAAAGTGTCAGCAATGGATTT
TATCTTTAAAGATGATCCAAGCCAATTACAGTCCAGAATTATTGATTGCTTAGAAACTGCACACACTCGCTTAAAATTAT
TATCTAAAGAAAGTACTGTTGAAACGATTGAATTGAAACGAGGAAGTAATTCAATTTATGTTCAATATGATGACGTAATG
TTTTTCGAATCATCTACAAAATCACATCGATTAATCGCACATTTAGATAATCGTCAAATTGAGTTCTATGGCAATTTAAA
AGAACTTGCACAACTTGATGAGCGGTTCTTTAGATGTCACAACAGCTTCGTTGTTAACAGACATAATATTGAATCCATAG
ATTCAAAAGAACGTATTGTCAATTTTAAAAACGGTGAGCACTGTTTTGCTTCGGTTCGTAATGTTAAAAAAATATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4L7S3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878

Multiple sequence alignment