Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HAC_RS00235 Genome accession   NC_008229
Coordinates   49172..49915 (+) Length   247 a.a.
NCBI ID   WP_011577036.1    Uniprot ID   Q17ZL2
Organism   Helicobacter acinonychis str. Sheeba     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 44172..54915
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HAC_RS00210 (Hac_0047) panD 46291..46641 (+) 351 WP_041600152.1 aspartate 1-decarboxylase -
  HAC_RS00215 (Hac_0048) - 46652..46945 (+) 294 WP_011577033.1 YbaB/EbfC family nucleoid-associated protein -
  HAC_RS00220 (Hac_0049) - 46945..47940 (+) 996 WP_011577034.1 PDZ domain-containing protein -
  HAC_RS00225 (Hac_0050) comB6 47948..49012 (+) 1065 WP_011577035.1 P-type conjugative transfer protein TrbL Machinery gene
  HAC_RS00230 comB7 49038..49175 (+) 138 WP_041600153.1 hypothetical protein Machinery gene
  HAC_RS00235 (Hac_0052) comB8 49172..49915 (+) 744 WP_011577036.1 type IV secretion system protein Machinery gene
  HAC_RS00240 (Hac_0053) comB9 49915..50865 (+) 951 WP_011577037.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HAC_RS00245 (Hac_0054) comB10 50858..51994 (+) 1137 WP_011577038.1 DNA type IV secretion system protein ComB10 Machinery gene
  HAC_RS00250 (Hac_0055) - 52059..53471 (+) 1413 WP_041600249.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HAC_RS00255 (Hac_0056) gmd 53481..54626 (+) 1146 WP_011577040.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28706.95 Da        Isoelectric Point: 9.2839

>NTDB_id=26063 HAC_RS00235 WP_011577036.1 49172..49915(+) (comB8) [Helicobacter acinonychis str. Sheeba]
MKEKPFNSEQLAFLEELLSHQEKHLENKLSSFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISLLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSNAKVWQRFEDLIKTNNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APRNKSD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=26063 HAC_RS00235 WP_011577036.1 49172..49915(+) (comB8) [Helicobacter acinonychis str. Sheeba]
ATGAAAGAAAAGCCTTTCAACAGCGAGCAATTGGCTTTTTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTCTCTAGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTAGGTTGGAGAGAAACCGCTTGAAAATCGCTT
ACAAACTTTTAGGTTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTTTTAATCAGCCTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAATCAAGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCTAGCAA
TGAAGCCTTGGCTCGCTCACTGATTGGGGCGTATGTGTTAAACAGAGAGAGCATTAATCGCATTGACGATAAGTCGCGCT
ATGAATTGGTGCGTTTACAAAGCAACGCTAAAGTGTGGCAGCGCTTTGAAGATTTGATTAAAACCAACAACAGCATTTAT
GCACAAAGCCACTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATTTATCAGCAAGACAATAACCCCATTGCAAGCGT
GTCCATTGCCGCCAAACTCTTGAATGAAAACAAATTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATCTTTTTG
ACACTCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTTACTCGCTATAGCATCACCGAAATT
GCACCTAGAAATAAGAGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q17ZL2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

94.332

100

0.943

Multiple sequence alignment