Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   CXP43_RS18130 Genome accession   NZ_CP025308
Coordinates   3571529..3572125 (+) Length   198 a.a.
NCBI ID   WP_003151513.1    Uniprot ID   I2CAH7
Organism   Bacillus velezensis strain Lzh-a42     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 3566529..3577125
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXP43_RS18105 (CXP43_18105) - 3566543..3566854 (+) 312 WP_007407407.1 hypothetical protein -
  CXP43_RS18115 (CXP43_18115) - 3567205..3568674 (-) 1470 WP_014418948.1 glycoside hydrolase family 32 protein -
  CXP43_RS18120 (CXP43_18120) - 3568689..3569921 (-) 1233 WP_007613980.1 MFS transporter -
  CXP43_RS18125 (CXP43_18125) - 3570311..3571285 (+) 975 WP_014418949.1 LacI family DNA-binding transcriptional regulator -
  CXP43_RS18130 (CXP43_18130) clpP 3571529..3572125 (+) 597 WP_003151513.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  CXP43_RS18135 (CXP43_18135) pgmB 3572170..3572859 (-) 690 WP_014418950.1 beta-phosphoglucomutase -
  CXP43_RS18140 (CXP43_18140) - 3572856..3574541 (-) 1686 WP_014418951.1 glycoside hydrolase family 13 protein -
  CXP43_RS18145 (CXP43_18145) - 3574534..3576807 (-) 2274 WP_014418952.1 glycoside hydrolase family 65 protein -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21831.06 Da        Isoelectric Point: 4.6982

>NTDB_id=259998 CXP43_RS18130 WP_003151513.1 3571529..3572125(+) (clpP) [Bacillus velezensis strain Lzh-a42]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLEAEDPEKDISIYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSADEALEYGLIDKVLTRNTEDQK

Nucleotide


Download         Length: 597 bp        

>NTDB_id=259998 CXP43_RS18130 WP_003151513.1 3571529..3572125(+) (clpP) [Bacillus velezensis strain Lzh-a42]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGAGAAAGAGCTTATGACATTTACTCCCGTCTTTTGAAGGA
CCGTATTATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCCTTGAAGCGG
AAGACCCTGAAAAAGATATTTCCATTTACATTAACAGCCCTGGCGGATCAATCACTGCCGGTATGGCAATCTATGATACA
ATGCAGTTCATTAAACCGAAAGTATCCACGATCTGCATCGGTATGGCCGCTTCTATGGGAGCATTTTTACTTGCAGCCGG
AGAAAAAGGCAAACGTTACGCGCTTCCTAACAGTGAAGTTATGATTCACCAGCCGCTTGGCGGAGCGCAAGGACAGGCGA
CAGAAATTGAAATCGCGGCAAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTGCTTGCTGAACGTACCGGCCAG
CCGCTTGAAGTCATTGAGCGCGATACAGACCGCGACAACTTCAAATCAGCTGATGAAGCCTTAGAATACGGCTTAATCGA
TAAAGTGCTGACACGCAATACAGAAGACCAGAAGTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2CAH7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

95.96

100

0.96
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.586

96.465

0.662
  clpP Streptococcus thermophilus LMG 18311

58.549

97.475

0.571
  clpP Streptococcus thermophilus LMD-9

58.549

97.475

0.571
  clpP Streptococcus pneumoniae D39

57.216

97.98

0.561
  clpP Streptococcus pneumoniae Rx1

57.216

97.98

0.561
  clpP Streptococcus pneumoniae R6

57.216

97.98

0.561
  clpP Streptococcus pneumoniae TIGR4

57.216

97.98

0.561
  clpP Lactococcus lactis subsp. cremoris KW2

56.701

97.98

0.556
  clpP Streptococcus pyogenes JRS4

55.44

97.475

0.54
  clpP Streptococcus pyogenes MGAS315

55.44

97.475

0.54
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

54.639

97.98

0.535
  clpP Streptococcus mutans UA159

54.639

97.98

0.535

Multiple sequence alignment