Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Machinery gene
Locus tag   CXP43_RS14240 Genome accession   NZ_CP025308
Coordinates   2848995..2849747 (-) Length   250 a.a.
NCBI ID   WP_014418548.1    Uniprot ID   I2C8I4
Organism   Bacillus velezensis strain Lzh-a42     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2843995..2854747
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXP43_RS14215 (CXP43_14215) mreC 2844431..2845294 (-) 864 WP_007408166.1 rod shape-determining protein MreC -
  CXP43_RS14220 (CXP43_14220) mreB 2845325..2846338 (-) 1014 WP_003152647.1 cell shape-determining protein MreB -
  CXP43_RS14225 (CXP43_14225) radC 2846430..2847125 (-) 696 WP_007408165.1 RadC family protein -
  CXP43_RS14230 (CXP43_14230) - 2847157..2847726 (-) 570 WP_012118105.1 Maf family protein -
  CXP43_RS14235 (CXP43_14235) - 2847867..2848868 (-) 1002 WP_014418547.1 SPOR domain-containing protein -
  CXP43_RS14240 (CXP43_14240) comC 2848995..2849747 (-) 753 WP_014418548.1 prepilin peptidase Machinery gene
  CXP43_RS14245 (CXP43_14245) - 2849887..2851179 (-) 1293 WP_014418549.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  CXP43_RS14250 (CXP43_14250) - 2851238..2853880 (-) 2643 WP_014418550.1 valine--tRNA ligase -
  CXP43_RS14255 (CXP43_14255) - 2854333..2854524 (+) 192 WP_003152639.1 hypothetical protein -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 27261.96 Da        Isoelectric Point: 9.4293

>NTDB_id=259989 CXP43_RS14240 WP_014418548.1 2848995..2849747(-) (comC) [Bacillus velezensis strain Lzh-a42]
MLLFLFFLGLIFGSFFYTAACRIPLRISVISPRSACSFCRLPLSWGELVPVVSYILQRGRCRNCRAKLSVMYPAAECWTA
CLFTAAGIHFGFSKELLVALLFLSLLMIVTVTDLQYMLIPDKVLLFFLPLFIAGRMFSPLDTWYAGFAGAVCGFFLLVFI
MFVSKGGIGAGDVKLFGVIGLPLGVKLVLIAFFLSVMIGTVYGMCAAARGRLGKKQPFPFAPAISAGSALSYLYGEELFS
FYIKLASGGA

Nucleotide


Download         Length: 753 bp        

>NTDB_id=259989 CXP43_RS14240 WP_014418548.1 2848995..2849747(-) (comC) [Bacillus velezensis strain Lzh-a42]
GTGCTTTTGTTTCTGTTTTTTCTCGGCTTGATTTTCGGTTCTTTTTTTTATACAGCAGCGTGCCGTATCCCGCTTCGAAT
CTCGGTTATTTCGCCGCGTTCAGCCTGTTCGTTTTGCCGCTTGCCGCTCTCCTGGGGGGAGCTTGTGCCCGTCGTTTCCT
ATATTCTGCAAAGAGGCAGATGCAGAAACTGCCGTGCGAAGCTGTCGGTTATGTATCCGGCGGCGGAATGCTGGACGGCG
TGTTTATTCACGGCTGCAGGCATTCATTTCGGTTTCTCAAAAGAACTGTTAGTCGCGCTGTTATTTCTGTCTCTGCTCAT
GATTGTTACCGTGACGGATCTGCAATATATGCTGATTCCTGACAAGGTTCTGCTGTTTTTTCTTCCGCTTTTCATTGCCG
GCCGTATGTTTTCTCCGCTGGATACATGGTATGCAGGGTTTGCCGGAGCCGTTTGCGGATTTTTTCTGCTTGTTTTTATC
ATGTTTGTCAGTAAAGGAGGCATCGGCGCAGGTGATGTGAAACTGTTTGGGGTGATCGGCCTGCCGCTCGGCGTGAAGCT
CGTGCTCATTGCATTCTTTCTTTCCGTTATGATCGGAACCGTATACGGTATGTGCGCCGCAGCCCGGGGCAGGCTTGGTA
AAAAGCAGCCATTTCCGTTTGCGCCGGCCATCTCAGCCGGGAGCGCTTTGAGTTATTTATACGGAGAAGAGCTGTTTTCG
TTTTACATCAAGCTCGCTTCAGGCGGAGCTTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-90)

Type IV leader peptidase family (Peptidase_A24)

(101-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C8I4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Bacillus subtilis subsp. subtilis str. 168

58.065

99.2

0.576

Multiple sequence alignment