Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   CSC59_RS03960 Genome accession   NZ_CP030326
Coordinates   748011..748685 (+) Length   224 a.a.
NCBI ID   WP_001166500.1    Uniprot ID   Q99VW2
Organism   Staphylococcus aureus strain AR_474     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 743011..753685
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSC59_RS03930 (CSC59_0457) - 743226..744293 (+) 1068 WP_000980137.1 membrane protein -
  CSC59_RS03935 (CSC59_0458) - 744444..745487 (+) 1044 WP_001030772.1 alpha/beta hydrolase -
  CSC59_RS03945 (CSC59_0459) - 745816..746244 (+) 429 WP_000198504.1 hypothetical protein -
  CSC59_RS03950 (CSC59_0460) - 746453..746959 (-) 507 WP_000940129.1 GNAT family N-acetyltransferase -
  CSC59_RS03955 (CSC59_0461) graX 747072..747995 (+) 924 WP_000802953.1 auxiliary protein GraX/ApsX -
  CSC59_RS03960 (CSC59_0462) braR 748011..748685 (+) 675 WP_001166500.1 response regulator transcription factor GraR/ApsR Regulator
  CSC59_RS03965 (CSC59_0463) graS 748678..749718 (+) 1041 WP_001061264.1 histidine kinase GraS/ApsS -
  CSC59_RS03970 (CSC59_0464) vraF 749862..750623 (+) 762 WP_000985996.1 ABC transporter ATP-binding protein VraF -
  CSC59_RS03975 (CSC59_0465) vraG 750613..752502 (+) 1890 WP_000143608.1 ABC transporter permease VraG -
  CSC59_RS15610 - 752574..752645 (-) 72 Protein_706 hypothetical protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 26065.87 Da        Isoelectric Point: 4.3563

>NTDB_id=259766 CSC59_RS03960 WP_001166500.1 748011..748685(+) (braR) [Staphylococcus aureus strain AR_474]
MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSR
DNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDDTIFLSKTEMIIL
EILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGKGYMAHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=259766 CSC59_RS03960 WP_001166500.1 748011..748685(+) (braR) [Staphylococcus aureus strain AR_474]
ATGCAAATACTACTAGTAGAAGATGACAATACTTTGTTTCAAGAATTGAAAAAAGAATTAGAACAATGGGATTTTAATGT
TGCTGGTATTGAAGATTTCGGCAAAGTAATGGATACATTTGAAAGTTTTAATCCTGAAATTGTTATATTGGATGTTCAAT
TACCTAAATATGATGGGTTTTATTGGTGCAGAAAAATGAGAGAAGTTTCCAACGTACCAATATTATTTTTATCATCTCGT
GATAATCCAATGGATCAAGTGATGAGTATGGAACTTGGCGCAGATGATTATATGCAAAAACCTTTCTATACCAATGTATT
AATTGCTAAATTACAAGCGATTTATCGTCGTGTCTATGAGTTTACAGCTGAAGAAAAACGTACATTGACTTGGCAAGATG
CTGTCGTTGATCTATCAAAAGATAGTATACAAAAAGGTGACGATACGATTTTTCTATCCAAAACAGAAATGATTATATTA
GAAATTCTTATTACCAAAAAAAATCAAATCGTTTCGAGAGATACAATTATCACTGCATTATGGGATGATGAAGCATTTGT
TAGTGATAATACGTTAACAGTAAATGTGAATCGTTTACGAAAAAAATTATCTGAAATTAGTATGGATAGTGCAATCGAAA
CAAAAGTAGGAAAAGGATATATGGCTCATGAATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(149-221)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q99VW2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

40.455

98.214

0.397