Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   DQ228_RS09160 Genome accession   NZ_CP030250
Coordinates   1778858..1779151 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain CS20     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1773858..1784151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQ228_RS09120 - 1774259..1774702 (-) 444 WP_011681680.1 hypothetical protein -
  DQ228_RS09125 - 1774776..1775114 (-) 339 WP_224103197.1 CPBP family intramembrane glutamic endopeptidase -
  DQ228_RS09130 - 1775158..1775433 (-) 276 WP_011681681.1 hypothetical protein -
  DQ228_RS09135 - 1775445..1775643 (-) 199 Protein_1785 helix-turn-helix transcriptional regulator -
  DQ228_RS09140 - 1775892..1777085 (-) 1194 WP_014608740.1 acetate kinase -
  DQ228_RS09145 comGH 1777141..1778097 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  DQ228_RS09150 comGG 1778142..1778459 (-) 318 WP_011681685.1 competence type IV pilus minor pilin ComGG Machinery gene
  DQ228_RS09155 comGF 1778437..1778874 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQ228_RS09160 comGE 1778858..1779151 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQ228_RS09165 comGD 1779123..1779551 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQ228_RS09170 comGC 1779511..1779837 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  DQ228_RS09175 comGB 1779834..1780934 (-) 1101 WP_120764773.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQ228_RS09180 comGA/cglA/cilD 1780816..1781757 (-) 942 WP_022096896.1 competence type IV pilus ATPase ComGA Machinery gene
  DQ228_RS09185 - 1781838..1782200 (-) 363 WP_014622006.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=259573 DQ228_RS09160 WP_011226625.1 1778858..1779151(-) (comGE) [Streptococcus thermophilus strain CS20]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=259573 DQ228_RS09160 WP_011226625.1 1778858..1779151(-) (comGE) [Streptococcus thermophilus strain CS20]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361

Multiple sequence alignment