Detailed information NTG0258990

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: DP112_RS10665
• Genome accession: NZ_CP030125
• Coordinates: 2149348..2151888 (-)
• Length: 846 a.a.
• NCBI ID: WP_114866961.1
• Uniprot ID: -
• Organism: Streptococcus suis strain HA1003
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2144348..2156888

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DP112_RS10635 (DP112_10640)	-	2145506..2146249 (-)	744	WP_013730659.1	amino acid ABC transporter ATP-binding protein	-
DP112_RS10640 (DP112_10645)	-	2146249..2147052 (-)	804	WP_014637221.1	amino acid ABC transporter permease	-
DP112_RS10645 (DP112_10650)	-	2147238..2148089 (-)	852	WP_114866960.1	amino acid ABC transporter substrate-binding protein	-
DP112_RS10650 (DP112_10655)	-	2148122..2148808 (-)	687	WP_024401035.1	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	-
DP112_RS10655 (DP112_10660)	-	2148922..2149095 (-)	174	WP_002941962.1	hypothetical protein	-
DP112_RS11485	-	2149129..2149251 (-)	123	WP_230333842.1	DUF3021 family protein	-
DP112_RS10665 (DP112_10670)	hexA	2149348..2151888 (-)	2541	WP_114866961.1	DNA mismatch repair protein MutS	Machinery gene
DP112_RS10670 (DP112_10675)	argR	2151903..2152343 (-)	441	WP_002937036.1	arginine repressor	-
DP112_RS10675 (DP112_10680)	argS	2152450..2154138 (+)	1689	WP_114866962.1	arginine--tRNA ligase	-
DP112_RS10680 (DP112_10685)	-	2154318..2155232 (+)	915	WP_114866963.1	SH3 domain-containing protein	-
DP112_RS10685 (DP112_10690)	-	2155286..2155810 (-)	525	WP_024384267.1	membrane protein	-
DP112_RS10690 (DP112_10695)	-	2155922..2156104 (+)	183	WP_024384268.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95074.54 Da
• Isoelectric Point: 4.8806

>NTDB_id=258990 DP112_RS10665 WP_114866961.1 2149348..2151888(-) (hexA) [Streptococcus suis strain HA1003]
MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSQEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNIPAIKNILQQINEPALGNLVAGLDPIPELHALISSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPSHFFRKA
TLKNSERYGTEELAKIEGQMLEARDKSANLEYEIFMRIRQEVEKYISRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVILAQMGSYVPADQAALPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLERADRILQTLENQAPTAPANPAPSVV
EEPSGQLDLFADTPSHPVLDELEKLDIYNMTPMEVMMRVAELKKKL

Nucleotide

• Length: 2541 bp

>NTDB_id=258990 DP112_RS10665 WP_114866961.1 2149348..2151888(-) (hexA) [Streptococcus suis strain HA1003]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAGTTATTTTATGAAGATGCGGTAGAAGCGGCACAGATTTTGGAATTGTCCTTGACCAGTC
GGAATAAGAATGCGGAGAATCCGATTCCTATGGCGGGGGTACCGTATCACGCGGCCCAGCAGTATATCGACACACTTGTT
GAATTGGGGCATAAGGTCGCTATTGCTGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAGGTAGT
GCAGGTCATTACTCCTGGTACGGTAACAGATTCGTCCAAAATGGGAGCCGACAGTAACTATTTGGTTGCGATTGACCGTC
AGGGAGTGCAGTTCGCACTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACCAGT
CTTTGCGGTGAAATCCGCAATTTACGGGCACGTGAATTGGTCATCGGCTATGCTCTGTCGCAGGAAGAGGAGCAGGTTTT
CTCGAATCAGATGAACTTGTTGCTGTCTTTTGAAGATGAGGTGACGGAGGATGTTCAGCTGATTGACAACTCGCTGACGG
ACTTGGAAAAGGCTGCGGCGGGTAAACTCCTCAGCTACCTACATCGGACTCAGATGCGGGATTTGAGTCACTTGCAAAAG
GTGGTCCACTATGAAATCAAGGACTATCTGCAAATGGACTATGCAACCAAGTCCAGTCTGGACCTGCTTGAAAACGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTATTGGTTGCTAGACGAAACCAAGACAGCCATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCCTTGATTGACCTTAAGCGGATTGAGAATCGTCAGGCTGTCGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTCGAGGCTTTGAAGGGTGTCTATGACATCGAACGCTTGGCCAGTCGGGTGTCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAGCTCTCCCAGACTTTGGGAAATATCCCAGCAATCAAGAATATCTTGCAACAAATCAATG
AGCCTGCTCTAGGCAATCTGGTAGCTGGATTGGACCCAATTCCAGAACTGCATGCTCTCATCAGCTCTGCTATTGACCCA
GAAGCCCAAGGGACCATCACAGATGGAAATATCATCCGTACGGGCTTTGACGAAACGCTGGATCAGTACCGTCTGGTCAT
GCGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCCAAGGAGCGTGAAGCGTCTGGTATCAATAATCTCAAGATTGATT
ACAACAAAAAAGACGGCTACTATTTCCATGTGACCAATTCCAATCTGGGCAATGTGCCTAGTCATTTCTTCCGTAAGGCG
ACCTTGAAAAACTCGGAGCGCTATGGAACGGAAGAGTTGGCTAAGATCGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
TGCTAATTTGGAGTACGAGATTTTCATGCGGATTCGCCAAGAGGTTGAGAAGTACATCAGTCGCTTGCAGAAGTTGGCTC
GGACCATTGCAACCATCGATGTTTTGCAGGCCTTTGCAGTTGTGGCGGAGCAGCAACATTTGGTTTGTCCACGCTTTACA
GATCAAAGAGAACTAACCATTGACCGTGGACGTCATGCAGTGGTGGAGAAGGTCATGGGCAAGCAGACCTATATTCCCAA
CTCTATTCACTTGAATACCGATACGCATATGCAACTGATTACAGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGGC
AGTTGGCGGTTATTGTCATTCTGGCGCAGATGGGTTCTTATGTGCCTGCGGATCAGGCTGCATTGCCGATTTTCGATGCT
ATTTTCACTCGGATTGGGGCGGCAGATGACCTGGTCAGTGGTCAATCCACCTTTATGGTCGAAATGATGGAGGCCAACAA
GGCGGTCCGTCTGGCGACAGATCGGTCTCTCATCCTCTTTGACGAACTTGGACGGGGAACGGCCACCTATGACGGTATGG
CCCTGGCCCAGTCTATCATCGAATACATCCACGACAAGATTGGAGCCAAGACCCTCTTTGCCACCCACTACCATGAGTTG
ACAGACCTTAGTCAGACCTTGGAACACTTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGACAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAGCTAT
TGGAGCGGGCGGATAGGATTTTGCAGACGCTTGAAAACCAAGCCCCTACTGCACCAGCTAACCCAGCTCCGTCAGTTGTG
GAAGAACCGTCAGGTCAACTTGACCTCTTCGCAGACACGCCTTCTCACCCAGTCCTCGATGAACTGGAGAAACTAGACAT
CTACAATATGACCCCAATGGAAGTCATGATGAGGGTGGCAGAATTGAAGAAAAAATTATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (256-546)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.759	100	0.738
mutS	Pseudomonas stutzeri strain ATCC 17587	37.326	100	0.379