Detailed information NTG0025863

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: MGAS9429_RS07125
• Genome accession: NC_008021
• Coordinates: 1423138..1423863 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes MGAS9429
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1418138..1428863

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS9429_RS07090 (MGAS9429_Spy1467)	-	1418272..1418655 (+)	384	WP_002988673.1	ImmA/IrrE family metallo-endopeptidase	-
MGAS9429_RS07095 (MGAS9429_Spy1468)	-	1418666..1419217 (+)	552	WP_002988670.1	hypothetical protein	-
MGAS9429_RS07100 (MGAS9429_Spy1469)	-	1419334..1420413 (+)	1080	WP_002988667.1	site-specific integrase	-
MGAS9429_RS07110 (MGAS9429_Spy1470)	trmB	1420611..1421246 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
MGAS9429_RS07115 (MGAS9429_Spy1471)	ccrZ	1421246..1422037 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
MGAS9429_RS07120 (MGAS9429_Spy1472)	-	1422101..1423135 (-)	1035	WP_002988663.1	ABC transporter permease	-
MGAS9429_RS07125 (MGAS9429_Spy1473)	pptA	1423138..1423863 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
MGAS9429_RS07130 (MGAS9429_Spy1474)	-	1423935..1424354 (+)	420	WP_002988659.1	HIT family protein	-
MGAS9429_RS07135 (MGAS9429_Spy1475)	-	1424351..1424707 (+)	357	WP_002988657.1	hypothetical protein	-
MGAS9429_RS07140 (MGAS9429_Spy1476)	brpA	1424818..1426098 (-)	1281	WP_002988654.1	biofilm formation/cell division transcriptional regulator BrpA	-
MGAS9429_RS07145 (MGAS9429_Spy1477)	-	1426107..1426631 (-)	525	WP_002988650.1	GNAT family N-acetyltransferase	-
MGAS9429_RS07150 (MGAS9429_Spy1478)	tsaE	1426606..1427067 (-)	462	WP_002988647.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
MGAS9429_RS07155 (MGAS9429_Spy1479)	-	1427221..1428681 (-)	1461	WP_002988645.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=25863 MGAS9429_RS07125 WP_002983379.1 1423138..1423863(-) (pptA) [Streptococcus pyogenes MGAS9429]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=25863 MGAS9429_RS07125 WP_002983379.1 1423138..1423863(-) (pptA) [Streptococcus pyogenes MGAS9429]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714