Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   MGAS9429_RS01415 Genome accession   NC_008021
Coordinates   268652..269722 (+) Length   356 a.a.
NCBI ID   WP_002986002.1    Uniprot ID   Q1JNF7
Organism   Streptococcus pyogenes MGAS9429     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 263652..274722
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS9429_RS01400 (MGAS9429_Spy0251) amiA 264180..266150 (+) 1971 WP_024623426.1 peptide ABC transporter substrate-binding protein Regulator
  MGAS9429_RS01405 (MGAS9429_Spy0252) amiC 266215..267717 (+) 1503 WP_002991105.1 ABC transporter permease Regulator
  MGAS9429_RS01410 (MGAS9429_Spy0253) amiD 267717..268643 (+) 927 WP_002986004.1 oligopeptide ABC transporter permease OppC Regulator
  MGAS9429_RS01415 (MGAS9429_Spy0254) amiE 268652..269722 (+) 1071 WP_002986002.1 ABC transporter ATP-binding protein Regulator
  MGAS9429_RS01420 (MGAS9429_Spy0255) amiF 269715..270638 (+) 924 WP_002986000.1 ATP-binding cassette domain-containing protein Regulator
  MGAS9429_RS10040 - 270623..270760 (-) 138 Protein_235 IS3 family transposase -
  MGAS9429_RS01425 (MGAS9429_Spy0256) - 270787..270966 (-) 180 WP_100215900.1 transposase -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 39749.85 Da        Isoelectric Point: 5.7015

>NTDB_id=25837 MGAS9429_RS01415 WP_002986002.1 268652..269722(+) (amiE) [Streptococcus pyogenes MGAS9429]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGRQITEVIIKHQKVSNAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=25837 MGAS9429_RS01415 WP_002986002.1 268652..269722(+) (amiE) [Streptococcus pyogenes MGAS9429]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGACAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTAATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-299)

ABC transporter (ABC_tran)

(29-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q1JNF7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

76.389

100

0.772
  amiE Streptococcus thermophilus LMG 18311

75.278

100

0.761
  amiE Streptococcus thermophilus LMD-9

75.278

100

0.761
  oppD Streptococcus mutans UA159

56.677

94.663

0.537

Multiple sequence alignment