Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   CWI64_RS08970 Genome accession   NZ_CP025076
Coordinates   1663807..1664496 (+) Length   229 a.a.
NCBI ID   WP_000518016.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BHN97x     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1658807..1669496
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI64_RS08945 (CWI64_08945) gpsB 1658916..1659245 (+) 330 WP_000146522.1 cell division regulator GpsB -
  CWI64_RS08955 (CWI64_08955) - 1659731..1660888 (+) 1158 WP_000711391.1 class I SAM-dependent RNA methyltransferase -
  CWI64_RS08960 (CWI64_08960) mapZ 1660901..1662295 (+) 1395 WP_000039276.1 mid-cell-anchored protein MapZ -
  CWI64_RS08965 (CWI64_08965) gndA 1662371..1663795 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  CWI64_RS08970 (CWI64_08970) covR 1663807..1664496 (+) 690 WP_000518016.1 response regulator transcription factor Regulator
  CWI64_RS08975 (CWI64_08975) cbpC 1664594..1665559 (+) 966 WP_000771105.1 choline-binding protein CbpC -
  CWI64_RS08980 (CWI64_08980) cbpJ 1665578..1666576 (+) 999 WP_000771134.1 choline-binding protein CbpJ -
  CWI64_RS08985 (CWI64_08985) - 1666694..1667926 (-) 1233 WP_000765664.1 MFS transporter -
  CWI64_RS08990 (CWI64_08990) - 1668085..1668555 (-) 471 WP_211286270.1 lanthionine synthetase LanC family protein -
  CWI64_RS08995 (CWI64_08995) - 1668455..1668793 (-) 339 WP_001820155.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26932.24 Da        Isoelectric Point: 6.9836

>NTDB_id=258118 CWI64_RS08970 WP_000518016.1 1663807..1664496(+) (covR) [Streptococcus pneumoniae strain BHN97x]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=258118 CWI64_RS08970 WP_000518016.1 1663807..1664496(+) (covR) [Streptococcus pneumoniae strain BHN97x]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGTAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment