Detailed information NTG0258017

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: CWI35_RS06210
• Genome accession: NZ_CP025074
• Coordinates: 1180993..1183578 (-)
• Length: 861 a.a.
• NCBI ID: WP_020279632.1
• Uniprot ID: U2X7R5
• Organism: [Bacillus] caldolyticus strain NEB414
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1175993..1188578

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CWI35_RS06180 (CWI35_06170)	fabF	1176706..1177944 (-)	1239	WP_011230306.1	beta-ketoacyl-ACP synthase II	-
CWI35_RS06185 (CWI35_06175)	-	1177985..1178917 (-)	933	WP_014195167.1	beta-ketoacyl-ACP synthase III	-
CWI35_RS06190 (CWI35_06180)	-	1179176..1179427 (+)	252	WP_014195166.1	hypothetical protein	-
CWI35_RS06195 (CWI35_06185)	-	1179462..1180202 (-)	741	WP_014195165.1	alpha/beta hydrolase	-
CWI35_RS06200 (CWI35_06190)	-	1180336..1180524 (+)	189	WP_025039308.1	YjzD family protein	-
CWI35_RS06210 (CWI35_06200)	clpC	1180993..1183578 (-)	2586	WP_020279632.1	ATP-dependent chaperone ClpB	Regulator
CWI35_RS06215 (CWI35_06205)	-	1183686..1183865 (-)	180	WP_011230299.1	YjzC family protein	-
CWI35_RS06220 (CWI35_06210)	argF	1184056..1184994 (-)	939	WP_013146083.1	ornithine carbamoyltransferase	-
CWI35_RS06225 (CWI35_06215)	-	1184991..1188119 (-)	3129	WP_025039307.1	carbamoyl phosphate synthase large subunit	-

Sequence

Protein

• Length: 861 a.a.
• Molecular weight: 96895.00 Da
• Isoelectric Point: 5.4605

>NTDB_id=258017 CWI35_RS06210 WP_020279632.1 1180993..1183578(-) (clpC) [[Bacillus] caldolyticus strain NEB414]
MDASRLTEKLQEALMAAQSLAKERHHQQLDVEHLLIALLEQEGGLAPRLVELSGADKEKAADWLRSQLRQKPEVHGADGQ
LYVAPALARLLEEAENEAKRMQDEYISVEHVLLALPHGAEPVARQLASFGLTKEALLAAVRNVRGNQRVTSPHPEATYEA
LAKYGRDLVAEAKAGKIDPVIGRDSEIRRIIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPEGLKDKTIFAL
DMSALVAGAKFRGEFEERLKAVLNEIKKSDGRIILFIDELHTIVGAGRAEGAIDAGNMLKPMLARGELRCIGATTLDEYR
QYIEKDPALERRFQQVLVQEPSVEDTISILRGLKERYEVHHGVKIHDRALVAAAVLSDRYISDRFLPDKAIDLVDEACAT
IRTEMESMPSELDEVMRRVMQLEIEEAALSKETDEASRERLAALQKELADLREKANAMKAQWQKEKEALDRVRRLREALE
RAKRELEEAENEYDLNKAAELRHGRIPQLEKQLKQLEQEISEQSEGKLLREEVTEEEIAEIVSRWTGIPLTRLVEGEREK
LLRLHELLHRRVIGQDEAVELVADAVLRARAGMKDPNRPIGSFLFLGPTGVGKTELAKALAEALFDSEEQLIRLDMSEYM
EKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVLLFDEIEKAHPEVFNILLQLLDDGRLTDSQGRTVDFKNTVVIMTS
NIGSPLLLENKHGDIDEETRKQVFEQLRAHFRPEFLNRIDDIVLFKPLSMNEVKGIVEKFARELSARLADRHIELVLTEA
AKQYIAEAGFDPVYGARPLKRFMQKQIETPLAKELIAGRVKDYSTVTVDVDNGQIAIRPSA

Nucleotide

• Length: 2586 bp

>NTDB_id=258017 CWI35_RS06210 WP_020279632.1 1180993..1183578(-) (clpC) [[Bacillus] caldolyticus strain NEB414]
ATGGACGCAAGCCGTTTGACGGAAAAACTGCAAGAGGCGCTGATGGCGGCGCAGTCGCTCGCCAAAGAACGACATCATCA
ACAGCTTGATGTCGAGCATCTCCTGATTGCGCTGCTCGAACAAGAAGGCGGCCTGGCGCCGCGGCTCGTGGAGCTTTCCG
GCGCCGACAAGGAAAAGGCCGCTGACTGGCTTCGCAGCCAGCTTCGCCAAAAGCCTGAAGTGCATGGGGCGGACGGGCAG
CTGTATGTTGCGCCCGCCTTAGCGCGGCTGCTTGAGGAGGCGGAAAACGAAGCGAAGCGAATGCAAGACGAGTACATATC
GGTCGAACATGTGCTGCTCGCGTTGCCTCATGGCGCCGAGCCGGTCGCTCGGCAGCTGGCGTCGTTTGGACTGACGAAGG
AAGCACTATTAGCGGCAGTGAGAAACGTAAGGGGGAATCAACGCGTGACGAGTCCACATCCGGAAGCAACCTATGAAGCG
TTGGCAAAATACGGGCGCGACCTTGTCGCGGAAGCGAAAGCGGGAAAAATCGACCCGGTCATCGGCCGCGACAGTGAAAT
TCGCCGCATCATCCGCATTTTGTCGCGGAAGACGAAAAACAACCCGGTGTTGATCGGCGAGCCGGGCGTCGGGAAGACCG
CTATTGTCGAAGGGCTCGCTCAACGCATCGTGCGCAAAGATGTCCCGGAAGGGCTGAAAGACAAAACGATTTTCGCTCTT
GATATGAGCGCGCTCGTCGCCGGAGCAAAGTTTCGCGGTGAATTTGAAGAACGGCTGAAAGCGGTGTTAAACGAAATCAA
AAAAAGCGACGGCCGCATCATTTTATTTATTGACGAGCTGCATACGATCGTCGGCGCCGGCAGAGCGGAAGGGGCGATTG
ACGCCGGCAATATGCTCAAGCCGATGCTTGCCCGCGGCGAGCTGCGCTGCATCGGGGCGACGACGCTTGATGAGTACCGG
CAATACATCGAAAAAGACCCGGCGCTCGAGCGCCGCTTCCAACAAGTGCTTGTCCAAGAGCCGAGTGTCGAGGACACGAT
TTCGATTTTGCGCGGATTGAAAGAACGGTATGAAGTGCACCATGGAGTGAAAATCCACGATCGCGCGCTCGTCGCGGCCG
CCGTTTTGTCCGACCGTTACATCTCTGACCGCTTTTTGCCTGACAAAGCGATCGATTTGGTCGATGAAGCGTGCGCGACG
ATCCGGACGGAAATGGAATCGATGCCGTCGGAGCTGGACGAAGTGATGCGCCGCGTCATGCAGCTTGAAATTGAAGAGGC
GGCCTTAAGCAAAGAAACGGATGAAGCGAGCCGCGAGCGGCTTGCGGCATTGCAAAAAGAACTTGCCGATTTGCGTGAAA
AGGCGAACGCCATGAAAGCGCAATGGCAAAAAGAAAAAGAGGCGCTTGACCGCGTCCGCCGTTTGCGCGAGGCGCTCGAG
CGGGCAAAACGCGAACTGGAAGAGGCGGAAAACGAGTATGATTTAAACAAGGCGGCGGAGCTTCGCCATGGCCGCATTCC
GCAGTTGGAAAAGCAACTCAAACAGCTCGAGCAAGAAATCAGTGAGCAAAGTGAAGGGAAATTGCTGCGCGAGGAAGTGA
CGGAAGAAGAGATTGCCGAAATCGTGTCACGCTGGACTGGCATTCCGCTCACCCGCCTCGTCGAGGGAGAGAGGGAAAAG
CTGCTTCGCCTTCATGAATTGCTGCATAGACGGGTCATCGGTCAAGACGAAGCGGTCGAGCTTGTCGCTGACGCCGTCTT
GCGGGCGCGGGCCGGCATGAAAGACCCGAACCGCCCGATCGGATCGTTTTTGTTCCTCGGACCGACCGGCGTCGGCAAAA
CGGAACTGGCCAAAGCGCTCGCCGAGGCGCTGTTTGACAGTGAGGAGCAGCTCATCCGTCTTGACATGTCCGAGTATATG
GAAAAACACGCCGTCTCCCGCTTGATCGGAGCGCCGCCCGGCTATGTCGGCTATGAGGAAGGCGGCCAGCTGACCGAGGC
GGTGCGGCGCAAGCCGTATTCCGTTCTGTTGTTCGATGAAATCGAAAAAGCTCATCCGGAAGTGTTCAACATCCTGTTGC
AGCTGCTGGATGACGGACGGCTCACCGATTCGCAAGGGCGGACGGTCGACTTTAAAAACACGGTCGTCATTATGACATCG
AACATCGGATCGCCGCTGTTGTTAGAAAACAAACATGGCGACATCGATGAAGAAACGCGCAAACAAGTGTTCGAACAACT
GCGCGCCCATTTCCGCCCAGAATTTTTAAACCGGATCGACGATATCGTCTTATTTAAGCCATTGTCGATGAATGAAGTGA
AAGGCATCGTCGAAAAGTTCGCCCGCGAGCTGTCGGCCCGTTTGGCCGATCGGCATATCGAACTCGTGCTGACCGAAGCG
GCGAAGCAATACATCGCCGAAGCGGGCTTCGACCCAGTATACGGCGCCCGCCCGCTCAAACGGTTTATGCAAAAGCAAAT
CGAAACGCCGCTTGCGAAAGAGCTGATCGCTGGGCGGGTGAAAGATTACAGCACCGTCACGGTCGATGTTGACAACGGGC
AGATCGCCATTCGTCCGTCGGCGTAA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-60)

• AAA domain (Cdc48 subfamily) (AAA_2) (598-762)

• AAA lid domain (AAA_lid_9) (342-444)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (768-848)

3D structure

• AlphaFold DB: U2X7R5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.368	100	0.481
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.686	100	0.425
clpC	Lactococcus lactis subsp. cremoris KW2	45.543	83.391	0.38