Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   A7J09_RS00385 Genome accession   NZ_CP030015
Coordinates   72907..74844 (+) Length   645 a.a.
NCBI ID   WP_029178410.1    Uniprot ID   -
Organism   Streptococcus suis strain ISU2812     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 67907..79844
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J09_RS00370 (A7J09_00370) comR 68388..69290 (+) 903 WP_024399278.1 helix-turn-helix domain-containing protein Regulator
  A7J09_RS00375 (A7J09_00375) - 69855..71075 (+) 1221 WP_029178408.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  A7J09_RS00380 (A7J09_00385) - 71266..72789 (+) 1524 WP_029178409.1 quinol oxidase -
  A7J09_RS00385 (A7J09_00390) hexB 72907..74844 (+) 1938 WP_029178410.1 DNA mismatch repair endonuclease MutL Machinery gene
  A7J09_RS00390 (A7J09_00395) ruvA 74883..75473 (+) 591 WP_015646243.1 Holliday junction branch migration protein RuvA Machinery gene
  A7J09_RS00395 (A7J09_00400) - 75727..76296 (+) 570 WP_024394300.1 DNA-3-methyladenine glycosylase I -
  A7J09_RS00400 (A7J09_00405) cinA 76333..77514 (+) 1182 WP_024394301.1 competence/damage-inducible protein A Machinery gene
  A7J09_RS00405 (A7J09_00410) recA 77566..78717 (+) 1152 WP_024387809.1 recombinase RecA Machinery gene
  A7J09_RS00410 (A7J09_00415) spx 78953..79351 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  A7J09_RS00415 (A7J09_00420) - 79451..79717 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72914.09 Da        Isoelectric Point: 5.1101

>NTDB_id=257928 A7J09_RS00385 WP_029178410.1 72907..74844(+) (hexB) [Streptococcus suis strain ISU2812]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKNQSDLFRIRTLGFRGEALPSIASVSHMIIETATADSAHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFALVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRVILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENK
PTSVQFAERQTAESTDPEHPNLSTKELAKLADKLDQEETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALDLVHKMDAFRQVGVNLEEYGANQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=257928 A7J09_RS00385 WP_029178410.1 72907..74844(+) (hexB) [Streptococcus suis strain ISU2812]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTCAAAA
TGATTCAAATTACGGATAACGGTGAGGGGATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAATCAATCGGATTTGTTTCGTATTCGCACCCTCGGTTTTCGTGGAGAAGCTCTGCCCTCCATTGCTTCTGTCAG
TCATATGATCATTGAGACAGCTACGGCAGACTCTGCACACGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCAGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAC
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCCTT
TGCCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCTGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTATGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCCATTTTCATCAACGGTCGCTATATCAAGAATTTTTTGCTGAATCGAGT
AATTTTGGAAGGTTACGGCAGTAAGTTGATGGTTGGACGCTTTCCATTGGCAGTCATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCACTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTTTTAA
AACCAGATGTTGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAAA
CCTACCTCTGTTCAATTTGCAGAACGCCAGACAGCTGAAAGTACAGACCCAGAACACCCTAACTTGAGTACTAAAGAGTT
GGCCAAATTAGCAGACAAACTAGACCAAGAAGAAACCTCAACCTTCCCAGAATTGGAATATTTTGGTCAAATGCACGGCA
CCTATCTTTTTGCACAAGGAAAAACAGGACTGTATATCATTGACCAGCATGCCGCACAAGAGCGGGTCAAATACGAATAC
TATCGTGAGAAAATTGGTCAGGTTGACAATTCAGCTCAACAGTTATTGGTGCCGTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTTGTCCACAAAATGGATGCCTTCCGTCAAGTTGGTGTCAACTTAGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAGGAGATTGAGTCTGGCATTTATGAGATGTGCGACATGTTGCTCTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCCATCATGATGTCTTGTAAACGGTCAATCAAGGCCAATCA
TGCCTTGGATGATTATTCGGCGCGTGATTTATTGAGACAATTGTCTTACTGCCAAAATCCCTATAACTGCCCGCACGGCC
GCCCAGTCTTAGTACATTTTAGCAAATCGGATATGGAAAAAATGTTCCGTCGCATTCAAGAAAATCACACGAGTTTGCGT
GAATTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

MutL C terminal dimerisation domain (MutL_C)

(447-589)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.308

100

0.729