Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   CFC57_RS10890 Genome accession   NZ_CP029751
Coordinates   2109159..2109872 (+) Length   237 a.a.
NCBI ID   WP_001031454.1    Uniprot ID   A0A0H2XG68
Organism   Staphylococcus aureus strain Smith     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2104159..2114872
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CFC57_RS10820 (CFC57_11260) - 2104907..2105170 (-) 264 WP_001205732.1 hypothetical protein -
  CFC57_RS10825 (CFC57_11265) - 2105179..2105439 (-) 261 WP_000291506.1 DUF1108 family protein -
  CFC57_RS10830 (CFC57_11270) - 2105444..2105746 (-) 303 WP_000165371.1 DUF2482 family protein -
  CFC57_RS10835 (CFC57_11275) - 2105841..2106002 (-) 162 WP_000048131.1 DUF1270 family protein -
  CFC57_RS10840 (CFC57_11280) - 2105999..2106322 (-) 324 WP_001806402.1 DUF771 domain-containing protein -
  CFC57_RS10845 (CFC57_11285) - 2106381..2106608 (+) 228 WP_000801108.1 hypothetical protein -
  CFC57_RS10850 (CFC57_11290) - 2106610..2106801 (-) 192 WP_000389906.1 hypothetical protein -
  CFC57_RS10855 (CFC57_11295) - 2106851..2107207 (+) 357 WP_000768245.1 DUF2513 domain-containing protein -
  CFC57_RS10860 (CFC57_11300) - 2107202..2107396 (-) 195 WP_001148859.1 hypothetical protein -
  CFC57_RS10865 (CFC57_11305) - 2107412..2108164 (-) 753 WP_001148605.1 phage antirepressor KilAC domain-containing protein -
  CFC57_RS10870 (CFC57_11310) - 2108215..2108544 (+) 330 WP_000128907.1 hypothetical protein -
  CFC57_RS10875 (CFC57_11315) - 2108533..2108748 (-) 216 WP_001025404.1 MW1434 family type I TA system toxin -
  CFC57_RS10880 (CFC57_11320) - 2108764..2109027 (-) 264 WP_000854072.1 helix-turn-helix transcriptional regulator -
  CFC57_RS10885 (CFC57_11325) - 2109024..2109196 (-) 173 Protein_2078 transcriptional regulator -
  CFC57_RS10890 (CFC57_11330) irvR 2109159..2109872 (+) 714 WP_001031454.1 XRE family transcriptional regulator Regulator
  CFC57_RS10895 (CFC57_11335) - 2109888..2110820 (+) 933 WP_000759683.1 exonuclease domain-containing protein -
  CFC57_RS10900 (CFC57_11340) - 2110826..2111167 (+) 342 WP_000591749.1 hypothetical protein -
  CFC57_RS10905 (CFC57_11345) - 2111371..2111553 (+) 183 WP_000705240.1 hypothetical protein -
  CFC57_RS10910 (CFC57_11350) - 2111631..2112344 (+) 714 WP_001549185.1 type II toxin-antitoxin system PemK/MazF family toxin -
  CFC57_RS10915 (CFC57_11355) - 2112535..2113572 (+) 1038 WP_000857173.1 site-specific integrase -
  CFC57_RS10920 (CFC57_11360) sph 2113623..2114453 (+) 831 Protein_2085 sphingomyelin phosphodiesterase -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27017.58 Da        Isoelectric Point: 5.0545

>NTDB_id=257697 CFC57_RS10890 WP_001031454.1 2109159..2109872(+) (irvR) [Staphylococcus aureus strain Smith]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide


Download         Length: 714 bp        

>NTDB_id=257697 CFC57_RS10890 WP_001031454.1 2109159..2109872(+) (irvR) [Staphylococcus aureus strain Smith]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(127-236)

Helix-turn-helix (HTH_3)

(13-63)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XG68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

33.929

100

0.401