Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   CWR44_RS12695 Genome accession   NZ_CP025031
Coordinates   2572315..2573031 (+) Length   238 a.a.
NCBI ID   WP_011275301.1    Uniprot ID   Q4L7S3
Organism   Staphylococcus haemolyticus strain SGAir0252     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2567315..2578031
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWR44_RS12670 (CWR44_12620) - 2567946..2568569 (+) 624 WP_011275306.1 nitroreductase family protein -
  CWR44_RS12675 (CWR44_12625) - 2568762..2569547 (+) 786 WP_011275305.1 carbon-nitrogen family hydrolase -
  CWR44_RS12680 (CWR44_12630) - 2570277..2570843 (+) 567 WP_033079903.1 accessory gene regulator AgrB -
  CWR44_RS12685 (CWR44_12635) agrD 2570846..2570986 (+) 141 WP_033079904.1 cyclic lactone autoinducer peptide AgrD -
  CWR44_RS12690 (CWR44_12640) agrC 2571013..2572296 (+) 1284 WP_033079905.1 quorum-sensing sensor histidine kinase AgrC -
  CWR44_RS12695 (CWR44_12645) agrA 2572315..2573031 (+) 717 WP_011275301.1 quorum-sensing response regulator AgrA Regulator
  CWR44_RS12700 (CWR44_12650) - 2573148..2574113 (-) 966 WP_037569564.1 carbohydrate kinase family protein -
  CWR44_RS12705 (CWR44_12655) - 2574117..2575601 (-) 1485 WP_037569561.1 sucrose-6-phosphate hydrolase -
  CWR44_RS12710 (CWR44_12660) - 2575686..2576645 (-) 960 WP_037569556.1 LacI family DNA-binding transcriptional regulator -
  CWR44_RS12715 (CWR44_12665) - 2576745..2577989 (-) 1245 WP_016931062.1 ammonium transporter -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27801.74 Da        Isoelectric Point: 5.2189

>NTDB_id=257510 CWR44_RS12695 WP_011275301.1 2572315..2573031(+) (agrA) [Staphylococcus haemolyticus strain SGAir0252]
MKIFICEDDVKQRENMVSIINNYIMIEEKPMEIALATDDPYEVIEKSKEMNDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPSQLQSRIIDCLETAHTRLKLLSKESTVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVVNRHNIESIDSKERIVNFKNGEHCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=257510 CWR44_RS12695 WP_011275301.1 2572315..2573031(+) (agrA) [Staphylococcus haemolyticus strain SGAir0252]
ATGAAAATATTCATTTGTGAAGATGATGTAAAACAACGCGAAAATATGGTTTCAATTATTAATAATTACATTATGATTGA
AGAAAAACCTATGGAGATTGCGCTTGCAACAGACGATCCTTATGAAGTCATTGAAAAATCTAAAGAGATGAATGATGTCG
GATGTTACTTTCTAGATATTCAATTAGAGGCTGATATCAACGGTATTAAATTAGGTAGTGAAATTCGTAAGTATGACCCA
ATTGGGAATATCATATTCGTTACAAGTCATAGTGAGTTAACGTACCTAACCTTTGTTTACAAAGTGTCAGCGATGGATTT
TATCTTTAAAGATGATCCAAGCCAATTACAGTCCAGAATTATTGATTGCTTAGAAACTGCACATACCCGCTTAAAATTAT
TATCTAAAGAAAGTACTGTTGAGACGATTGAATTGAAACGAGGAAGTAATTCAATTTATGTTCAATATGATGACGTAATG
TTTTTCGAATCATCTACAAAATCACATCGGTTAATCGCACATTTAGATAATCGTCAAATTGAGTTCTATGGCAATTTAAA
AGAACTTGCACAACTTGATGAGCGGTTCTTTAGATGTCACAACAGCTTCGTTGTTAATAGACATAATATTGAATCCATAG
ATTCAAAAGAACGTATTGTCAATTTTAAAAACGGTGAGCACTGTTTTGCTTCCGTTCGTAATGTAAAAAAAATATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4L7S3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878

Multiple sequence alignment