Detailed information NTG0257248

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CKO49_RS09435
• Genome accession: NZ_CP025023
• Coordinates: 1931924..1932967 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus argenteus strain XNO106
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1926924..1937967

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CKO49_RS09405 (CKO49_09405)	-	1927335..1928582 (-)	1248	WP_000656301.1	aminopeptidase	-
CKO49_RS09410 (CKO49_09410)	-	1928594..1928794 (-)	201	WP_000180459.1	DUF1128 family protein	-
CKO49_RS09415 (CKO49_09415)	-	1928941..1929405 (+)	465	WP_000228669.1	low molecular weight protein-tyrosine-phosphatase	-
CKO49_RS09420 (CKO49_09420)	-	1929412..1929687 (+)	276	WP_000428174.1	YtxH domain-containing protein	-
CKO49_RS09425 (CKO49_09425)	-	1929966..1931189 (+)	1224	WP_000037065.1	YihY/virulence factor BrkB family protein	-
CKO49_RS09430 (CKO49_09430)	vraR	1931305..1931934 (-)	630	WP_000153529.1	two-component system response regulator VraR	Regulator
CKO49_RS09435 (CKO49_09435)	vraS	1931924..1932967 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
CKO49_RS09440 (CKO49_09440)	liaF	1932964..1933665 (-)	702	WP_031788217.1	cell wall-active antibiotics response protein LiaF	-
CKO49_RS09445 (CKO49_09445)	-	1933680..1934066 (-)	387	WP_001110170.1	hypothetical protein	-
CKO49_RS09450 (CKO49_09450)	map	1934287..1935045 (-)	759	WP_031788218.1	type I methionyl aminopeptidase	-
CKO49_RS09455 (CKO49_09455)	-	1935576..1936562 (+)	987	WP_031788370.1	aromatic acid exporter family protein	-
CKO49_RS09465 (CKO49_09465)	-	1937194..1937916 (-)	723	WP_031787877.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=257248 CKO49_RS09435 WP_001017131.1 1931924..1932967(-) (vraS) [Staphylococcus argenteus strain XNO106]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=257248 CKO49_RS09435 WP_001017131.1 1931924..1932967(-) (vraS) [Staphylococcus argenteus strain XNO106]
ATGAACCATTATATTAGAACAATTGGTTCGATGCTCATCTTAGTATACAGCATGCTAGCGGCATTTCTTTTTATAGATAA
AGTTTTCGTTAATATTATTTATTTTCAAGGCATGTTTTATACACAAATATTTGGGATTCCAGTCTTTTTATTTTTAAATC
TCATTATCATTTTATTGTGTATCATCGTCGGATCGGTGCTTGCCTACAAAATTAATCAACAAAATGATTGGATTAAGACA
CAAATTGAGCGTTCTATGGAAGGCGAAACAGTAGGTATCAATGATCAAAATATAGAAATATATAGTGAAACATTAGATTT
ATATCATACGTTAGTACCTTTAAATCAAGAATTGCATAAGTTAAGACTCAAAACGCAAAATTTAACAAATGAAAATTACA
ATATTAATGATGTTAAAGTTAAAAAGATTATCGAAGATGAAAGACAACGTTTAGCTAGAGAACTACACGACTCTGTTAGT
CAACAACTTTTTGCGGCAAGTATGATGTTATCTGCAATTAAAGAAACGAAATTAGAACCACCTTTAGATCAACAAATACC
TATTTTAGAGAAAATGGTTCAAGATTCTCAGTTAGAAATGCGTGCTTTGCTGCTACACTTAAGACCACTCGGCTTGAAAG
ATAAGTCATTAGGCGAAGGTATTAAAGATTTAGTTATTGATTTACAAAAGAAAGTGCCAATGAAAGTTGTGCATGAGATA
CAAGATTTTAAAGTGCCAAAAGGTATTGAAGATCATTTATTTAGAATTACGCAAGAAGCAATATCTAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTAGAATTATTTAATAAAGATGATTATTTATTGTTAAGGATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCACTACCAGATTCAGGTACACGTATTGAGGTGAAAGCACCTCTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1