Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   CU118_RS11175 Genome accession   NZ_CP024998
Coordinates   2153968..2154633 (-) Length   221 a.a.
NCBI ID   WP_054189714.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 55-99-44     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2148968..2159633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CU118_RS14365 - 2149468..2149551 (-) 84 Protein_2089 hypothetical protein -
  CU118_RS11160 (CU118_11160) - 2150209..2152209 (-) 2001 WP_054189711.1 ABC transporter permease -
  CU118_RS11165 (CU118_11165) - 2152206..2152961 (-) 756 WP_054189712.1 ABC transporter ATP-binding protein -
  CU118_RS11170 (CU118_11170) braS 2153070..2153957 (-) 888 WP_054189713.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  CU118_RS11175 (CU118_11175) braR 2153968..2154633 (-) 666 WP_054189714.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  CU118_RS11180 (CU118_11180) - 2154659..2154859 (-) 201 WP_054189715.1 hypothetical protein -
  CU118_RS11185 (CU118_11185) - 2155057..2156481 (+) 1425 WP_054189717.1 alkaline phosphatase -
  CU118_RS14460 (CU118_11190) - 2156541..2156642 (-) 102 WP_070016594.1 SE2200 family small protein -
  CU118_RS11195 (CU118_11195) - 2156763..2157218 (-) 456 WP_054189718.1 MarR family winged helix-turn-helix transcriptional regulator -
  CU118_RS11200 (CU118_11200) - 2157463..2158224 (-) 762 WP_054189719.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25444.57 Da        Isoelectric Point: 5.0976

>NTDB_id=257035 CU118_RS11175 WP_054189714.1 2153968..2154633(-) (braR) [Staphylococcus aureus strain 55-99-44]
MKILIVEDDFVIAESLASELKKWNYDVIVVKQFNDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQSIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=257035 CU118_RS11175 WP_054189714.1 2153968..2154633(-) (braR) [Staphylococcus aureus strain 55-99-44]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGATGT
TATTGTCGTTAAACAATTTAATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAATTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTATCAGTAGCTAATGATTCATTGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAGCATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTGAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAATATGACACGTCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

98.19

100

0.982

Multiple sequence alignment