Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   CU118_RS08010 Genome accession   NZ_CP024998
Coordinates   1549023..1549739 (+) Length   238 a.a.
NCBI ID   WP_054189591.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 55-99-44     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1544023..1554739
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CU118_RS07980 (CU118_07980) - 1544283..1544909 (+) 627 WP_054189595.1 nitroreductase family protein -
  CU118_RS07985 (CU118_07985) - 1545230..1546015 (+) 786 WP_054189594.1 carbon-nitrogen family hydrolase -
  CU118_RS14445 hld 1546611..1546691 (-) 81 WP_000046022.1 delta-hemolysin -
  CU118_RS07995 (CU118_07995) - 1546981..1547550 (+) 570 WP_054189593.1 accessory gene regulator AgrB -
  CU118_RS08000 (CU118_08000) agrD 1547547..1547687 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  CU118_RS08005 (CU118_08005) agrC 1547712..1549004 (+) 1293 WP_054189592.1 quorum-sensing sensor histidine kinase AgrC -
  CU118_RS08010 (CU118_08010) agrA 1549023..1549739 (+) 717 WP_054189591.1 quorum-sensing response regulator AgrA Regulator
  CU118_RS08015 (CU118_08015) - 1549811..1549919 (+) 109 Protein_1500 hypothetical protein -
  CU118_RS08020 (CU118_08020) - 1550116..1551075 (-) 960 WP_054189590.1 carbohydrate kinase family protein -
  CU118_RS08025 (CU118_08025) - 1551072..1552556 (-) 1485 WP_054189589.1 sucrose-6-phosphate hydrolase -
  CU118_RS08030 (CU118_08030) - 1552705..1553655 (-) 951 WP_054189588.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27904.92 Da        Isoelectric Point: 6.3001

>NTDB_id=257030 CU118_RS08010 WP_054189591.1 1549023..1549739(+) (agrA) [Staphylococcus aureus strain 55-99-44]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDNRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=257030 CU118_RS08010 WP_054189591.1 1549023..1549739(+) (agrA) [Staphylococcus aureus strain 55-99-44]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACCGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACTTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCCGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATAATCGCTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment