Detailed information NTG0257029

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CU118_RS07600
• Genome accession: NZ_CP024998
• Coordinates: 1472659..1473702 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 55-99-44
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1467659..1478702

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CU118_RS07570 (CU118_07570)	-	1468083..1469339 (-)	1257	WP_077446664.1	aminopeptidase	-
CU118_RS07575 (CU118_07575)	-	1469342..1469542 (-)	201	WP_000180460.1	DUF1128 family protein	-
CU118_RS07580 (CU118_07580)	-	1469689..1470153 (+)	465	WP_054189636.1	low molecular weight protein-tyrosine-phosphatase	-
CU118_RS07585 (CU118_07585)	-	1470160..1470435 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
CU118_RS07590 (CU118_07590)	-	1470713..1471930 (+)	1218	WP_000037088.1	YihY/virulence factor BrkB family protein	-
CU118_RS07595 (CU118_07595)	vraR	1472040..1472669 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
CU118_RS07600 (CU118_07600)	vraS	1472659..1473702 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
CU118_RS07605 (CU118_07605)	liaF	1473699..1474400 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
CU118_RS07610 (CU118_07610)	-	1474415..1474801 (-)	387	WP_001110179.1	hypothetical protein	-
CU118_RS07615 (CU118_07615)	map	1475018..1475776 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
CU118_RS07630 (CU118_07630)	-	1476594..1477580 (+)	987	WP_054189634.1	FUSC family protein	-
CU118_RS07645 (CU118_07645)	-	1478089..1478502 (-)	414	WP_077446671.1	hypothetical protein	-
CU118_RS07650 (CU118_07650)	-	1478531..1478641 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=257029 CU118_RS07600 WP_001017131.1 1472659..1473702(-) (vraS) [Staphylococcus aureus strain 55-99-44]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=257029 CU118_RS07600 WP_001017131.1 1472659..1473702(-) (vraS) [Staphylococcus aureus strain 55-99-44]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTTATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACGGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACAAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTCCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCACTTGGTTTAAAAG
ACAAATCATTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1