Detailed information NTG0256837

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: CV098_RS11075
• Genome accession: NZ_CP024958
• Coordinates: 2274725..2275753 (-)
• Length: 342 a.a.
• NCBI ID: WP_017865178.1
• Uniprot ID: A0AAE4T0V0
• Organism: Lactococcus lactis subsp. lactis strain G423
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2269725..2280753

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CV098_RS11050 (CV098_11050)	-	2270012..2270509 (-)	498	WP_003132662.1	nitroreductase family protein	-
CV098_RS11055 (CV098_11055)	-	2270496..2270705 (-)	210	WP_003132661.1	hypothetical protein	-
CV098_RS11060 (CV098_11060)	-	2270702..2271529 (-)	828	WP_026138971.1	radical SAM protein	-
CV098_RS12240	-	2271522..2272721 (-)	1200	WP_017865175.1	MFS transporter	-
CV098_RS12245	-	2272718..2273644 (-)	927	WP_017865176.1	radical SAM protein	-
CV098_RS11070 (CV098_11070)	-	2273747..2274604 (-)	858	WP_017865177.1	Rgg/GadR/MutR family transcriptional regulator	-
CV098_RS11075 (CV098_11075)	sepM	2274725..2275753 (-)	1029	WP_017865178.1	SepM family pheromone-processing serine protease	Regulator
CV098_RS11080 (CV098_11080)	coaD	2275740..2276237 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
CV098_RS11085 (CV098_11085)	rsmD	2276285..2276824 (-)	540	WP_050558566.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
CV098_RS11090 (CV098_11090)	-	2276995..2278215 (-)	1221	WP_012898647.1	MDR family MFS transporter	-
CV098_RS11095 (CV098_11095)	lmrP	2278299..2279525 (-)	1227	WP_017865180.1	multidrug efflux MFS transporter LmrP	-
CV098_RS11100 (CV098_11100)	-	2279713..2280207 (+)	495	WP_017865181.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37362.96 Da
• Isoelectric Point: 9.9183

>NTDB_id=256837 CV098_RS11075 WP_017865178.1 2274725..2275753(-) (sepM) [Lactococcus lactis subsp. lactis strain G423]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKNIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=256837 CV098_RS11075 WP_017865178.1 2274725..2275753(-) (sepM) [Lactococcus lactis subsp. lactis strain G423]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAAATATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

• PDZ domain (PDZ_2) (134-194)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.986	100	0.494