Detailed information NTG0256784

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: CSC58_RS01765
• Genome accession: NZ_CP029681
• Coordinates: 324312..325025 (-)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus strain AR_0473
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 319312..330025

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC58_RS01735 (CSC58_0324)	sph	319876..320706 (-)	831	Protein_323	sphingomyelin phosphodiesterase	-
CSC58_RS01740 (CSC58_0325)	-	320757..321794 (-)	1038	WP_000857198.1	site-specific integrase	-
CSC58_RS01745 (CSC58_0326)	-	321967..322506 (-)	540	WP_000391618.1	type II toxin-antitoxin system PemK/MazF family toxin	-
CSC58_RS01750 (CSC58_0327)	-	322646..322813 (-)	168	WP_031806878.1	hypothetical protein	-
CSC58_RS01755	-	323017..323358 (-)	342	WP_000591749.1	hypothetical protein	-
CSC58_RS01760 (CSC58_0328)	-	323364..324296 (-)	933	WP_000759682.1	exonuclease domain-containing protein	-
CSC58_RS01765 (CSC58_0329)	irvR	324312..325025 (-)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
CSC58_RS01770	-	324988..325161 (+)	174	WP_001801500.1	hypothetical protein	-
CSC58_RS01775 (CSC58_0330)	-	325158..325421 (+)	264	WP_000854072.1	helix-turn-helix transcriptional regulator	-
CSC58_RS01780 (CSC58_0331)	-	325437..325634 (+)	198	WP_001148862.1	hypothetical protein	-
CSC58_RS01785 (CSC58_0332)	-	325621..326001 (-)	381	WP_000762521.1	DUF2513 domain-containing protein	-
CSC58_RS01790 (CSC58_0333)	-	326056..326379 (+)	324	WP_001120201.1	DUF771 domain-containing protein	-
CSC58_RS01795	-	326376..326537 (+)	162	WP_000048132.1	DUF1270 family protein	-
CSC58_RS01800 (CSC58_0334)	-	326632..326934 (+)	303	WP_000165371.1	DUF2482 family protein	-
CSC58_RS01805 (CSC58_0335)	-	326939..327199 (+)	261	WP_000291510.1	DUF1108 family protein	-
CSC58_RS01810	-	327208..327471 (+)	264	WP_001205732.1	hypothetical protein	-
CSC58_RS01815 (CSC58_0336)	-	327480..329423 (+)	1944	WP_000700555.1	AAA family ATPase	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=256784 CSC58_RS01765 WP_001031454.1 324312..325025(-) (irvR) [Staphylococcus aureus strain AR_0473]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=256784 CSC58_RS01765 WP_001031454.1 324312..325025(-) (irvR) [Staphylococcus aureus strain AR_0473]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401