Detailed information NTG0256740

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: CV702_RS11070
• Genome accession: NZ_CP024954
• Coordinates: 2292132..2293160 (-)
• Length: 342 a.a.
• NCBI ID: WP_017865178.1
• Uniprot ID: A0AAE4T0V0
• Organism: Lactococcus lactis subsp. lactis strain F44
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2287132..2298160

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CV702_RS11045 (CV702_11055)	-	2287419..2287916 (-)	498	WP_003132662.1	nitroreductase family protein	-
CV702_RS11050 (CV702_11060)	-	2287903..2288112 (-)	210	WP_003132661.1	hypothetical protein	-
CV702_RS11055 (CV702_11065)	-	2288109..2288936 (-)	828	WP_026138971.1	radical SAM protein	-
CV702_RS12220	-	2288929..2290128 (-)	1200	WP_017865175.1	MFS transporter	-
CV702_RS12225	-	2290125..2291051 (-)	927	WP_017865176.1	radical SAM protein	-
CV702_RS11065 (CV702_11075)	-	2291154..2292011 (-)	858	WP_017865177.1	Rgg/GadR/MutR family transcriptional regulator	-
CV702_RS11070 (CV702_11080)	sepM	2292132..2293160 (-)	1029	WP_017865178.1	SepM family pheromone-processing serine protease	Regulator
CV702_RS11075 (CV702_11085)	coaD	2293147..2293644 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
CV702_RS11080 (CV702_11090)	rsmD	2293692..2294231 (-)	540	WP_050558566.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
CV702_RS11085 (CV702_11095)	-	2294402..2295622 (-)	1221	WP_012898647.1	MDR family MFS transporter	-
CV702_RS11090 (CV702_11100)	lmrP	2295706..2296932 (-)	1227	WP_017865180.1	multidrug efflux MFS transporter LmrP	-
CV702_RS11095 (CV702_11105)	-	2297120..2297614 (+)	495	WP_017865181.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37362.96 Da
• Isoelectric Point: 9.9183

>NTDB_id=256740 CV702_RS11070 WP_017865178.1 2292132..2293160(-) (sepM) [Lactococcus lactis subsp. lactis strain F44]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKNIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=256740 CV702_RS11070 WP_017865178.1 2292132..2293160(-) (sepM) [Lactococcus lactis subsp. lactis strain F44]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAAATATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

• PDZ domain (PDZ_2) (134-194)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.986	100	0.494