Detailed information NTG0256692

Bioinformatically predicted

Overview

• Name: comB6
• Type: Machinery gene
• Locus tag: CV723_RS07585
• Genome accession: NZ_CP024953
• Coordinates: 1557179..1558234 (-)
• Length: 351 a.a.
• NCBI ID: WP_000786677.1
• Uniprot ID: D7FG37
• Organism: Helicobacter pylori strain 7.13
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1552179..1563234

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CV723_RS07560 (CV723_07580)	-	1552716..1554128 (-)	1413	WP_001861341.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-
CV723_RS07565 (CV723_07585)	comB10	1554198..1555334 (-)	1137	WP_001045869.1	DNA type IV secretion system protein ComB10	Machinery gene
CV723_RS07570 (CV723_07590)	comB9	1555327..1556310 (-)	984	WP_001861340.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
CV723_RS07575 (CV723_07595)	comB8	1556310..1557053 (-)	744	WP_000660520.1	virB8 family protein	Machinery gene
CV723_RS07580 (CV723_07600)	comB7	1557050..1557163 (-)	114	WP_001217873.1	hypothetical protein	Machinery gene
CV723_RS07585 (CV723_07605)	comB6	1557179..1558234 (-)	1056	WP_000786677.1	P-type conjugative transfer protein TrbL	Machinery gene
CV723_RS07590 (CV723_07610)	-	1558242..1559237 (-)	996	WP_000468428.1	PDZ domain-containing protein	-
CV723_RS07595 (CV723_07615)	-	1559237..1559539 (-)	303	WP_000347926.1	YbaB/EbfC family nucleoid-associated protein	-
CV723_RS07600 (CV723_07620)	panD	1559542..1559895 (-)	354	WP_000142236.1	aspartate 1-decarboxylase	-
CV723_RS07605 (CV723_07625)	-	1559885..1562110 (-)	2226	WP_001051506.1	ATP-dependent Clp protease ATP-binding subunit	-
CV723_RS07610 (CV723_07630)	-	1562110..1562385 (-)	276	WP_000784899.1	ATP-dependent Clp protease adaptor ClpS	-
CV723_RS07615 (CV723_07635)	-	1562400..1562813 (-)	414	WP_001023005.1	universal stress protein	-

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 39908.89 Da
• Isoelectric Point: 8.5786

>NTDB_id=256692 CV723_RS07585 WP_000786677.1 1557179..1558234(-) (comB6) [Helicobacter pylori strain 7.13]
MKNDAYEIILSWFITPLTAILGRFAEFFLYTLHAQLVFNSVVALAFMLFAYRSLKEQNFFSASALTEALWFVGFFALFNY
ALKNPMHFYEFFQNAIFIAPNMIAQSLSQSLSNFSNHALSLDFIFNHGFYALSFISDLSHNEMSVWLFLSILQGLFLSVL
FAIIILVYLEVHVWCSLGVLFLAFGFFKTWRSVVVICLKKCFALGFYKPFLLLVGFLNVSVTKALIDAHMQEKQDLSLLL
VVALFLCCVFIIGVPFFINALFRVQNSLKETYKLATNLSANLSQNALNSLQYITTPPAPSSVSSSMNESVSKEKETHSPT
FKVETTQLDVKIPNFKQKKVKKDTINTKNEI

Nucleotide

• Length: 1056 bp

>NTDB_id=256692 CV723_RS07585 WP_000786677.1 1557179..1558234(-) (comB6) [Helicobacter pylori strain 7.13]
ATGAAAAATGACGCTTATGAGATTATTCTTTCTTGGTTTATCACGCCTCTCACGGCGATTTTAGGGCGTTTCGCTGAATT
TTTTCTCTACACTTTGCATGCGCAATTGGTGTTTAATAGCGTGGTCGCTTTGGCGTTCATGCTTTTTGCTTACAGGAGCT
TGAAGGAACAGAATTTCTTCAGCGCCAGCGCACTAACAGAAGCGTTATGGTTTGTGGGGTTTTTTGCGCTGTTTAACTAC
GCTTTAAAAAATCCCATGCATTTTTATGAATTTTTCCAAAACGCTATTTTTATTGCGCCTAACATGATCGCGCAGAGCCT
CTCTCAAAGCTTGAGTAACTTTTCTAACCACGCGCTTTCTTTAGATTTTATCTTTAATCATGGTTTTTATGCCCTTAGTT
TTATCAGCGATTTGAGCCATAATGAAATGTCTGTGTGGCTTTTTTTAAGCATTTTGCAAGGGCTTTTTTTGAGCGTGCTG
TTTGCGATCATCATTTTAGTGTATTTAGAAGTGCATGTGTGGTGCTCTTTAGGGGTGCTGTTTTTAGCGTTTGGGTTTTT
CAAAACCTGGAGGAGCGTTGTGGTTATATGCCTAAAAAAATGCTTCGCTCTTGGGTTTTACAAGCCTTTTTTGTTGTTGG
TGGGGTTTTTGAATGTGTCGGTTACTAAGGCTTTAATAGACGCTCATATGCAAGAAAAACAAGATTTAAGCCTTTTATTG
GTGGTAGCGTTATTTTTGTGTTGCGTTTTTATCATAGGCGTGCCTTTTTTCATCAACGCTTTGTTTAGGGTGCAAAACAG
CCTTAAAGAAACTTACAAACTCGCCACCAATTTGAGCGCTAACCTCAGCCAAAACGCCCTTAATTCCTTACAATATATCA
CGACCCCACCCGCTCCCTCTAGCGTTTCTTCTTCTATGAATGAAAGCGTCTCTAAAGAAAAAGAAACGCATTCCCCCACT
TTTAAGGTAGAAACCACTCAATTAGATGTAAAAATCCCAAATTTCAAGCAAAAAAAGGTTAAAAAGGATACAATAAATAC
AAAAAATGAAATTTAA

Domains

Predicted by InterproScan.

• TrbL/VirB6 plasmid conjugal transfer protein (TrbL) (44-254)

3D structure

• AlphaFold DB: D7FG37

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB6	Helicobacter pylori 26695	98.575	100	0.986