Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   CV730_RS04995 Genome accession   NZ_CP024946
Coordinates   1034332..1036116 (+) Length   594 a.a.
NCBI ID   WP_145728632.1    Uniprot ID   -
Organism   Helicobacter pylori strain B147     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1029332..1041116
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CV730_RS04965 (CV730_04980) motB 1030098..1030871 (+) 774 WP_097702056.1 flagellar motor protein MotB -
  CV730_RS04970 (CV730_04985) - 1030877..1031314 (+) 438 WP_001885597.1 hypothetical protein -
  CV730_RS04975 (CV730_04990) - 1031383..1033044 (+) 1662 WP_145728629.1 ABC transporter permease/substrate-binding protein -
  CV730_RS04980 (CV730_04995) - 1033046..1033696 (+) 651 WP_145728630.1 ATP-binding cassette domain-containing protein -
  CV730_RS04985 (CV730_05000) - 1033699..1033878 (-) 180 WP_000468798.1 hypothetical protein -
  CV730_RS04990 (CV730_05005) - 1033870..1034331 (+) 462 WP_145728631.1 hypothetical protein -
  CV730_RS04995 (CV730_05010) uvrC 1034332..1036116 (+) 1785 WP_145728632.1 excinuclease ABC subunit UvrC Machinery gene
  CV730_RS05000 (CV730_05015) - 1036127..1037392 (+) 1266 WP_108368147.1 homoserine dehydrogenase -
  CV730_RS05005 (CV730_05020) - 1037392..1037736 (+) 345 WP_145728633.1 YraN family protein -
  CV730_RS05010 (CV730_05025) trxA 1037828..1038148 (+) 321 WP_000020206.1 thioredoxin -
  CV730_RS05015 (CV730_05030) trxB 1038154..1039089 (+) 936 WP_000564420.1 thioredoxin-disulfide reductase -
  CV730_RS05020 (CV730_05035) - 1039461..1040282 (+) 822 WP_145728634.1 glycosyltransferase family 25 protein -
  CV730_RS05025 (CV730_05040) - 1040507..1040755 (-) 249 WP_000790555.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68548.78 Da        Isoelectric Point: 9.7497

>NTDB_id=256544 CV730_RS04995 WP_145728632.1 1034332..1036116(+) (uvrC) [Helicobacter pylori strain B147]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNSRASLRIQMMVKQIASLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSDEYAQMSELLTRRALDFTKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=256544 CV730_RS04995 WP_145728632.1 1034332..1036116(+) (uvrC) [Helicobacter pylori strain B147]
ATGGCTGATTTATTATCCAGTTTGAAAAACCTTTCTAACAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAACGCATCAAAAGCTATTTTTCTATCCGTAATAATGAAATCACGCCCA
ATTCTCGCGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTCTTTAGAAACGATTTTAGTGGAAAATGAGCAA
GACGCTTTGATTTTAGAAAACTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCCTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAACAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAGCAATTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGTGCAAGCAATAAGGCGGT
ATTGGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAACGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAGGATCTGATTTTAGAAGAAGCGCGATCGCTCTTCAAATTAGAATGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATAACGCATTCCAAAAAAACTCTTATCGGCG
CTACCATTTAAAAGGCTCTGATGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTACTAAAGAGC
CACCGCCTAATTTGTGGGTGATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGTTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

98.316

100

0.983

Multiple sequence alignment