Detailed information NTG0255527

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: CUB85_RS17675
• Genome accession: NZ_CP024797
• Coordinates: 3528932..3530095 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain TJ02
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3523932..3535095

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CUB85_RS17645	-	3524196..3524615 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
CUB85_RS17650	comFC	3524689..3525378 (-)	690	WP_197200179.1	phosphoribosyltransferase family protein	Machinery gene
CUB85_RS17655	-	3525384..3525668 (-)	285	WP_007407481.1	late competence development ComFB family protein	-
CUB85_RS17660	comFA	3525726..3527111 (-)	1386	WP_099320008.1	DEAD/DEAH box helicase	Machinery gene
CUB85_RS17665	-	3527220..3528068 (-)	849	WP_094031329.1	DegV family protein	-
CUB85_RS17670	degU	3528166..3528855 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
CUB85_RS17675	degS	3528932..3530095 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
CUB85_RS17680	-	3530318..3530965 (+)	648	WP_007407485.1	YigZ family protein	-
CUB85_RS17685	-	3530970..3532205 (+)	1236	WP_025285355.1	LCP family protein	-
CUB85_RS17690	-	3532304..3533380 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
CUB85_RS17695	tuaH	3533513..3534709 (-)	1197	WP_094031330.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=255527 CUB85_RS17675 WP_007407484.1 3528932..3530095(-) (degS) [Bacillus velezensis strain TJ02]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=255527 CUB85_RS17675 WP_007407484.1 3528932..3530095(-) (degS) [Bacillus velezensis strain TJ02]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951