Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   DLJ56_RS13615 Genome accession   NZ_CP029629
Coordinates   2617323..2619428 (+) Length   701 a.a.
NCBI ID   WP_001058988.1    Uniprot ID   Q8NUR7
Organism   Staphylococcus aureus strain MOK063     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 2612323..2624428
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DLJ56_RS13590 (DLJ56_13590) - 2612351..2612569 (+) 219 WP_000011687.1 sterile alpha motif-like domain-containing protein -
  DLJ56_RS13595 (DLJ56_13595) - 2612959..2613390 (+) 432 WP_000455861.1 CHAP domain-containing protein -
  DLJ56_RS13600 (DLJ56_13600) - 2613528..2614808 (-) 1281 WP_001180331.1 hydroxymethylglutaryl-CoA reductase, degradative -
  DLJ56_RS13605 (DLJ56_13605) - 2615062..2616228 (+) 1167 WP_000151982.1 hydroxymethylglutaryl-CoA synthase -
  DLJ56_RS13610 (DLJ56_13610) - 2616393..2616914 (-) 522 WP_000455994.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
  DLJ56_RS13615 (DLJ56_13615) clpE 2617323..2619428 (+) 2106 WP_001058988.1 ATP-dependent Clp protease ATP-binding subunit ClpL Regulator
  DLJ56_RS13620 (DLJ56_13620) - 2619490..2619660 (-) 171 WP_000111119.1 FeoB-associated Cys-rich membrane protein -
  DLJ56_RS13625 (DLJ56_13625) feoB 2619673..2621667 (-) 1995 WP_070001963.1 ferrous iron transport protein B -
  DLJ56_RS13630 (DLJ56_13630) - 2621679..2621906 (-) 228 WP_000932073.1 FeoA family protein -
  DLJ56_RS14750 - 2621997..2622077 (-) 81 Protein_2542 hypothetical protein -
  DLJ56_RS13635 (DLJ56_13635) - 2622096..2623415 (-) 1320 WP_001808146.1 ISL3-like element IS1181 family transposase -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77836.22 Da        Isoelectric Point: 4.6056

>NTDB_id=255349 DLJ56_RS13615 WP_001058988.1 2617323..2619428(+) (clpE) [Staphylococcus aureus strain MOK063]
MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISV
DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=255349 DLJ56_RS13615 WP_001058988.1 2617323..2619428(+) (clpE) [Staphylococcus aureus strain MOK063]
ATGAATAACGGTTTTTTCAATAGTGACTTTGATTCAATTTTTCGAAGAATGATGCAAGATATGCAAGGTTCAAATCAAGT
CGGTAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCTGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACAAAGACAACAAGGGCAACAAGGTGGCAACGGCAATTAT
TTAGAACAAATTGGTCGTAACCTTACGCAAGAAGCACGTGACGGTTTATTAGATCCAGTCATTGGTCGTGATAAAGAAAT
TCAAGAAACTGCTGAAGTCTTAAGTAGACGAACTAAAAACAATCCTATATTAGTTGGAGAAGCTGGTGTTGGTAAAACTG
CGATTGTTGAAGGTTTAGCACAGGCAATCGTTGAAGGAAATGTACCAGCAGCAATCAAAGACAAAGAAATTATTTCTGTA
GATATTTCATCATTAGAAGCTGGAACGCAATATCGTGGTGCTTTTGAAGAAAATATTCAAAAATTAATCGAAGGTGTTAA
ATCTTCACAAAATGCCGTACTATTCTTTGATGAAATCCATCAAATTATCGGTTCAGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTGAAACCTGCATTAAGTCGTGGTGAGATTTCTATTATTGGTGCAACAACACAAGATGAA
TATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTACTTGTTAATGAACCAAGTGCTAAAGA
TACTGTGGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGATGACGTATTAAAAG
CATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCGGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATTAAATCATTACAAGATAAATTAGAAA
ATAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCA
AGCTGTAGAAATGGTTTCACGTGCAATTCGCCGTAATCGTGCTGGGTTTGATGACGGCAACCGTCCAATTGGCAGTTTCC
TATTTGTTGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAATAAAGATGCA
CTGATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGATGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATACTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTAACATTGTTATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGTAATGACGCTGAAGAAAAAGATATTAT
GCACGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTGCAAGATATCGTCAACTTATTATTAGACGATGTACAAGTTACATTAGACAAAAAAGGTATTACGATGGACGTT
TCTCAAGATGCGAAAGATTGGTTAATTGAAGAAGGCTATGATGAAGAATTAGGTGCACGTCCATTAAGACGTATTGTTGA
ACAGCAAGTACGTGACAAAATTACAGATTATTATCTAGATCATACAGACGTTAAACATGTGGATATAGATGTTGAGGATA
ACGAATTAGTCGTAAAAGGTAAATAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(264-363)

AAA domain (Cdc48 subfamily) (AAA_2)

(448-603)

ATPase family associated with various cellular activities (AAA) (AAA)

(123-257)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(611-682)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8NUR7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

48.834

91.726

0.448
  clpE Streptococcus pneumoniae Rx1

48.298

88.017

0.425
  clpE Streptococcus pneumoniae D39

48.298

88.017

0.425
  clpE Streptococcus pneumoniae R6

48.298

88.017

0.425
  clpE Streptococcus pneumoniae TIGR4

48.298

88.017

0.425
  clpC Lactococcus lactis subsp. cremoris KW2

46.815

89.586

0.419
  clpC Bacillus subtilis subsp. subtilis str. 168

44.564

93.153

0.415
  clpC Streptococcus thermophilus LMD-9

44.392

90.3

0.401
  clpC Streptococcus thermophilus LMG 18311

44.076

90.3

0.398
  clpC Streptococcus pneumoniae TIGR4

44.175

88.16

0.389
  clpC Streptococcus pneumoniae Rx1

44.175

88.16

0.389
  clpC Streptococcus pneumoniae D39

44.175

88.16

0.389
  clpC Streptococcus mutans UA159

43.577

87.732

0.382
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

41.294

92.582

0.382