Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DMB38_RS05275 Genome accession   NZ_CP029618
Coordinates   1280771..1281466 (-) Length   231 a.a.
NCBI ID   WP_125934158.1    Uniprot ID   -
Organism   Streptomyces sp. WAC 06738     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1275771..1286466
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DMB38_RS05240 (DMB38_05255) - 1275857..1276384 (+) 528 WP_047015019.1 HNH endonuclease -
  DMB38_RS05245 (DMB38_05260) - 1276498..1277460 (-) 963 WP_047015020.1 SPFH domain-containing protein -
  DMB38_RS05250 (DMB38_05265) - 1277543..1277923 (-) 381 WP_047019791.1 NfeD family protein -
  DMB38_RS05255 (DMB38_05270) - 1278061..1278858 (-) 798 WP_047015021.1 ABC transporter ATP-binding protein -
  DMB38_RS05260 (DMB38_05275) - 1278974..1279771 (+) 798 WP_125934156.1 hypothetical protein -
  DMB38_RS05265 (DMB38_05280) - 1279909..1280148 (-) 240 WP_164715928.1 chaplin -
  DMB38_RS05270 (DMB38_05285) - 1280359..1280604 (-) 246 WP_125934157.1 chaplin -
  DMB38_RS05275 (DMB38_05290) vraR 1280771..1281466 (-) 696 WP_125934158.1 response regulator transcription factor Regulator
  DMB38_RS05280 (DMB38_05295) - 1281459..1282625 (-) 1167 WP_125934159.1 GAF domain-containing sensor histidine kinase -
  DMB38_RS05285 (DMB38_05300) - 1282783..1285371 (-) 2589 WP_240661986.1 FHA domain-containing protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24622.96 Da        Isoelectric Point: 5.6995

>NTDB_id=255097 DMB38_RS05275 WP_125934158.1 1280771..1281466(-) (vraR) [Streptomyces sp. WAC 06738]
MAETGEKQRTAGPDETAASGRIRVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGDEGVARTAELVPDVVLMDVKMPGT
DGIEALRRIRESGSAARVLVITSFTEQRTVVPALRAGAAGYVYKDVDPEALARAIRSVHAGHVLLQQDVAGALLAPEAGG
GPAQGRGTTLTEREREVLALIADGRSNREIARALVVSEKTVKTHVSNILMKLDLADRTQAALWAVRHGLSG

Nucleotide


Download         Length: 696 bp        

>NTDB_id=255097 DMB38_RS05275 WP_125934158.1 1280771..1281466(-) (vraR) [Streptomyces sp. WAC 06738]
GTGGCTGAGACGGGCGAGAAGCAGCGGACCGCGGGCCCGGACGAGACGGCCGCCTCCGGCCGGATCCGGGTGCTGCTGGT
CGACGACCACCAGGTCGTACGGCGCGGGCTGCGCACCTTCCTGGAGGTGCAGGACGACATCGAGGTCGTCGGCGAGGCCG
CCGACGGGGACGAGGGCGTGGCCCGTACCGCCGAGCTGGTGCCGGACGTGGTCCTCATGGACGTGAAGATGCCCGGCACC
GACGGCATCGAGGCGCTGCGCCGCATCCGCGAGTCCGGCAGCGCGGCACGCGTGCTGGTCATCACCAGCTTCACCGAGCA
GCGCACCGTCGTCCCCGCACTGCGCGCAGGCGCCGCGGGCTATGTCTACAAGGACGTCGACCCCGAGGCCCTGGCCAGGG
CGATCCGCTCGGTGCACGCCGGGCACGTGCTGCTCCAGCAGGACGTCGCCGGGGCGCTGCTGGCGCCGGAGGCCGGCGGC
GGCCCCGCGCAGGGCCGGGGGACGACGCTGACCGAGCGCGAGCGCGAGGTGCTGGCGCTGATCGCGGACGGCCGCTCGAA
CCGGGAGATCGCCCGCGCCCTCGTGGTCTCGGAGAAGACCGTGAAGACGCACGTGTCGAACATCCTGATGAAGCTCGACC
TGGCGGACCGTACGCAGGCCGCCCTCTGGGCCGTACGCCACGGCCTGAGCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(24-135)

Bacterial regulatory proteins, luxR family (GerE)

(169-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.712

90.043

0.403

Multiple sequence alignment