Detailed information NTG0254767

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: CS547_RS17210
• Genome accession: NZ_CP024647
• Coordinates: 3473447..3474610 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain Lzh-5
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3468447..3479610

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CS547_RS17180 (CS547_17155)	-	3468712..3469131 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
CS547_RS17185 (CS547_17160)	comFC	3469205..3469894 (-)	690	WP_197538213.1	ComF family protein	Machinery gene
CS547_RS17190 (CS547_17165)	-	3469900..3470184 (-)	285	WP_022553866.1	late competence development ComFB family protein	-
CS547_RS17195 (CS547_17170)	comFA	3470242..3471627 (-)	1386	WP_022553867.1	DEAD/DEAH box helicase	Machinery gene
CS547_RS17200 (CS547_17175)	-	3471735..3472583 (-)	849	WP_003151387.1	DegV family protein	-
CS547_RS17205 (CS547_17180)	degU	3472681..3473370 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
CS547_RS17210 (CS547_17185)	degS	3473447..3474610 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
CS547_RS17215 (CS547_17190)	-	3474833..3475480 (+)	648	WP_007407485.1	YigZ family protein	-
CS547_RS17220 (CS547_17195)	-	3475485..3476699 (+)	1215	WP_022553868.1	LCP family protein	-
CS547_RS17225 (CS547_17200)	-	3476799..3477875 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
CS547_RS17230 (CS547_17205)	-	3478007..3479203 (-)	1197	WP_022553869.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=254767 CS547_RS17210 WP_007407484.1 3473447..3474610(-) (degS) [Bacillus velezensis strain Lzh-5]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=254767 CS547_RS17210 WP_007407484.1 3473447..3474610(-) (degS) [Bacillus velezensis strain Lzh-5]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951