Detailed information NTG0254040

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: DKG71_RS33940
• Genome accession: NZ_CP029541
• Coordinates: 7844397..7847039 (-)
• Length: 880 a.a.
• NCBI ID: WP_109893838.1
• Uniprot ID: -
• Organism: Streptomyces sp. NEAU-S7GS2
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 7839397..7852039

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DKG71_RS33910 (DKG71_33910)	-	7839436..7839951 (-)	516	WP_199785465.1	helix-turn-helix domain-containing protein	-
DKG71_RS33915 (DKG71_33915)	-	7840051..7840623 (+)	573	WP_239472086.1	SDR family NAD(P)-dependent oxidoreductase	-
DKG71_RS33920 (DKG71_33920)	-	7841050..7841688 (-)	639	WP_109896621.1	haloacid dehalogenase-like hydrolase	-
DKG71_RS45040	-	7841745..7841867 (-)	123	WP_275427287.1	hypothetical protein	-
DKG71_RS33925 (DKG71_33925)	-	7841911..7843656 (-)	1746	WP_109893836.1	cyclic nucleotide-binding domain-containing thioredoxin-disulfide reductase	-
DKG71_RS33930 (DKG71_33930)	-	7843656..7843919 (-)	264	WP_018092858.1	UBP-type zinc finger domain-containing protein	-
DKG71_RS33935 (DKG71_33935)	trxA	7843948..7844391 (-)	444	WP_109896623.1	thioredoxin	-
DKG71_RS33940 (DKG71_33940)	clpC	7844397..7847039 (-)	2643	WP_109893838.1	ATP-dependent chaperone ClpB	Regulator
DKG71_RS33945 (DKG71_33945)	-	7847030..7847440 (-)	411	WP_109893840.1	chaperone modulator CbpM	-
DKG71_RS33950 (DKG71_33950)	-	7847437..7848393 (-)	957	WP_109893842.1	DnaJ C-terminal domain-containing protein	-
DKG71_RS33955 (DKG71_33955)	-	7848400..7848915 (-)	516	WP_109893844.1	nucleotide exchange factor GrpE	-
DKG71_RS33960 (DKG71_33960)	-	7848925..7850404 (-)	1480	Protein_6684	Hsp70 family protein	-
DKG71_RS33965 (DKG71_33965)	-	7850463..7850951 (-)	489	WP_109893846.1	general stress protein	-

Sequence

Protein

• Length: 880 a.a.
• Molecular weight: 97955.14 Da
• Isoelectric Point: 4.9522

>NTDB_id=254040 DKG71_RS33940 WP_109893838.1 7844397..7847039(-) (clpC) [Streptomyces sp. NEAU-S7GS2]
MDMNRLTQKSQEALQEAQTIAGRMDQTEVDGEHLLLALLDQPDGLVPRLFDQAGADTKALRASLMSELSRRPKVTGPGAT
PGQVYVTQRLAKLLDTAEQEAKRLKDEYVSVEHLVLALADEGSRTAAGRLLKEHGITKDVFLSALTRIRGNQRVTSATPE
AAYEALEKYGRDLVAEARSGKKDPVIGRDAEIRRVTQILSRKTKNNPVLIGDPGVGKTAIVEGLAQRIVRGDVPEGLREK
TIFSLDMSSLVAGAKYRGEFEERLQAVLSEVKAAEGRILLFVDELHTVVGAGGGAEGAMDAGNMLKPMLARGELHMIGAT
TLEEYRKHVESDAALERRFQQVLVDEPSVEDTVSILRGLRERLEVFHGVKIQDTALVAAATLSHRYISDRFLPDKAIDLV
DEACARLRTEIDSMPAELDEITRRVTRLEIEDAALAKETDAASRKRLEELRRELSDLRAEADAMNAQWEAERQAIRRVQE
LRQELEQVRQEAEEAERNYDLNRAAELRYGTLTELERRLAAEEDALAAKQGDTRLLREVVTEDEIAEIVAAWTGIPVTRL
QEGEREKLLRLDEILTERVIGQDEAVKLVTDAIIRARSGIRDPRRPIGSFIFLGPTGVGKTELAKALAAALFDTEESIVR
LDMSEYQERHTVSRLVGAPPGYVGYEEGGQLTEAVRRKPYSVVLFDEVEKAHADVFNTLLQVLDDGRITDAQGRTVDFRN
TVVIMTSNIGSAHLLDAVTPEGEIKPEARALVMGELQSHFRPEFLNRVDDVVLFKPLGMDQIKRIVELQFNDLRRRLAER
QITVELTERARELIAQQGFDPVYGARPLRRYISHEVETLVGRALIRGDVQDGTAIRVDAQNGELVVTYDRPAQPDHGMAA

Nucleotide

• Length: 2643 bp

>NTDB_id=254040 DKG71_RS33940 WP_109893838.1 7844397..7847039(-) (clpC) [Streptomyces sp. NEAU-S7GS2]
GTGGATATGAACCGGCTCACCCAGAAGTCCCAGGAAGCCCTTCAGGAAGCGCAGACGATCGCCGGCCGGATGGACCAGAC
CGAGGTCGACGGTGAGCATCTGCTGCTCGCCCTCCTCGACCAGCCGGACGGGCTGGTGCCGCGGCTCTTCGACCAAGCGG
GCGCCGACACCAAGGCGTTGCGCGCCTCGCTTATGAGCGAGCTGTCACGCAGACCGAAGGTGACCGGACCCGGCGCCACA
CCCGGCCAGGTGTACGTCACCCAGCGGCTGGCCAAGCTGCTGGACACCGCCGAGCAGGAGGCCAAGCGGCTCAAGGACGA
ATATGTGTCCGTGGAGCACCTCGTCCTGGCACTGGCCGATGAGGGCTCCAGGACCGCGGCGGGACGGCTGCTCAAGGAAC
ACGGCATCACCAAGGACGTCTTCCTGTCCGCGCTGACCCGCATCCGCGGCAACCAGCGGGTCACCTCGGCGACGCCCGAG
GCCGCGTACGAGGCGTTGGAGAAGTACGGCCGTGATCTGGTCGCCGAGGCGCGCAGCGGCAAGAAGGACCCGGTGATCGG
CCGGGACGCGGAGATCCGCCGCGTCACCCAGATCCTCAGCCGCAAGACGAAGAACAACCCCGTGCTGATCGGCGATCCGG
GCGTCGGCAAGACGGCCATCGTGGAGGGCCTGGCACAGCGGATCGTCCGCGGCGACGTCCCCGAGGGGCTGCGCGAGAAG
ACCATCTTCTCCCTCGATATGAGCTCGCTGGTGGCGGGCGCCAAATACCGCGGTGAGTTCGAGGAACGACTGCAGGCGGT
GCTGAGCGAGGTCAAGGCCGCCGAGGGGCGCATCCTGCTCTTCGTCGACGAACTCCACACGGTCGTCGGAGCCGGCGGCG
GCGCCGAGGGCGCGATGGACGCCGGCAACATGCTCAAGCCGATGCTCGCCCGCGGTGAGCTGCACATGATCGGCGCCACC
ACGCTGGAGGAGTACCGCAAGCACGTCGAGTCCGACGCCGCCCTCGAACGCCGCTTCCAGCAGGTCCTGGTGGACGAGCC
GAGCGTGGAGGACACCGTCTCCATCCTCCGCGGCCTGCGCGAACGTCTTGAGGTCTTCCACGGCGTGAAGATCCAGGACA
CCGCGCTGGTCGCCGCGGCCACCCTCAGCCACCGCTATATCTCCGACCGTTTCCTGCCGGACAAGGCCATCGACCTCGTC
GACGAGGCCTGCGCGCGGCTGCGCACCGAGATCGACTCCATGCCGGCCGAACTCGACGAGATCACCCGCCGGGTGACCCG
TCTGGAGATCGAGGATGCGGCCCTCGCAAAGGAGACCGACGCCGCCAGCCGTAAGCGGCTGGAGGAGCTCCGGCGCGAAC
TGTCCGACCTGCGCGCCGAGGCCGACGCCATGAACGCCCAGTGGGAGGCCGAACGCCAGGCCATCCGGCGAGTGCAGGAG
CTGCGTCAGGAACTGGAACAGGTGCGTCAGGAAGCGGAGGAGGCCGAACGCAACTACGACCTCAACCGCGCCGCCGAACT
GCGCTACGGCACACTCACCGAACTCGAACGCCGGCTGGCCGCCGAAGAGGACGCGCTCGCCGCCAAGCAGGGCGATACCC
GGCTCCTGCGCGAGGTCGTCACGGAGGACGAGATCGCCGAGATCGTCGCCGCCTGGACCGGCATCCCGGTGACCCGGCTG
CAGGAAGGCGAGCGGGAGAAGCTGCTGCGGCTCGACGAGATCCTCACCGAGCGGGTGATCGGCCAGGACGAGGCCGTCAA
GCTGGTCACCGACGCCATCATCCGGGCCCGCTCCGGCATCCGCGACCCGCGCCGTCCCATCGGCTCGTTCATCTTCCTCG
GCCCCACCGGCGTCGGAAAGACCGAACTGGCCAAGGCGCTGGCCGCGGCACTGTTCGACACCGAGGAGAGCATCGTCCGT
CTCGACATGAGCGAGTACCAGGAACGGCACACCGTCAGCAGACTGGTCGGAGCGCCGCCCGGATACGTCGGCTACGAGGA
GGGCGGTCAGCTCACCGAGGCGGTACGCCGCAAGCCCTACTCCGTGGTCCTGTTCGACGAGGTCGAGAAGGCACACGCCG
ATGTCTTCAACACCTTGCTGCAGGTACTCGACGACGGCCGGATCACCGACGCCCAAGGCCGCACCGTCGACTTCCGCAAC
ACCGTCGTCATCATGACCTCCAACATCGGATCCGCCCATCTGCTCGACGCGGTGACCCCCGAGGGCGAGATCAAACCCGA
GGCACGGGCCCTGGTCATGGGCGAACTGCAAAGCCACTTCCGCCCCGAGTTCCTCAACCGCGTCGACGACGTCGTGCTGT
TCAAGCCGCTGGGCATGGACCAGATCAAGCGCATCGTCGAACTGCAGTTCAACGACCTGCGCCGGCGCCTGGCCGAACGC
CAGATCACCGTCGAACTCACCGAGCGGGCCCGCGAGCTCATCGCCCAGCAGGGCTTCGACCCCGTCTACGGGGCACGGCC
GCTGCGCCGCTACATCTCGCACGAGGTCGAAACACTCGTCGGGCGGGCCCTGATCCGCGGCGATGTACAGGACGGCACGG
CGATCCGGGTCGACGCCCAGAACGGTGAACTGGTCGTGACGTACGACAGGCCGGCCCAGCCCGACCACGGAATGGCTGCG
TGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (348-450)

• ATPase family associated with various cellular activities (AAA) (AAA) (208-340)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (777-857)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-150)

• AAA domain (Cdc48 subfamily) (AAA_2) (605-770)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	44.178	99.545	0.44
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.123	99.205	0.408
clpC	Lactococcus lactis subsp. cremoris KW2	46.02	78.523	0.361