Detailed information NTG0253791

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: DK181_RS10415
• Genome accession: NZ_CP029490
• Coordinates: 2129410..2131971 (-)
• Length: 853 a.a.
• NCBI ID: WP_002960565.1
• Uniprot ID: A0ABN5LPH4
• Organism: Streptococcus sobrinus strain SL1
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2124410..2136971

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK181_RS10395 (DK182_10395)	-	2124699..2125250 (-)	552	WP_002960562.1	DNA-3-methyladenine glycosylase I	-
DK181_RS10400 (DK182_10400)	ruvA	2125419..2126009 (-)	591	WP_002960563.1	Holliday junction branch migration protein RuvA	Machinery gene
DK181_RS10405 (DK182_10405)	hexB	2126241..2128232 (-)	1992	WP_002960564.1	DNA mismatch repair endonuclease MutL	Machinery gene
DK181_RS10410 (DK182_10410)	-	2128413..2129377 (-)	965	Protein_1986	DUF3644 domain-containing protein	-
DK181_RS10415 (DK182_10415)	hexA	2129410..2131971 (-)	2562	WP_002960565.1	DNA mismatch repair protein MutS	Machinery gene
DK181_RS10420 (DK182_10420)	-	2131958..2132311 (-)	354	WP_019795383.1	YlbF family regulator	-
DK181_RS10425 (DK182_10425)	argR	2132304..2132738 (-)	435	WP_002960568.1	arginine repressor	-
DK181_RS10430 (DK182_10430)	argS	2132894..2134585 (+)	1692	WP_002960570.1	arginine--tRNA ligase	-
DK181_RS10435 (DK182_10435)	-	2134798..2135157 (-)	360	WP_002960574.1	hypothetical protein	-
DK181_RS10440 (DK182_10440)	-	2135196..2135423 (-)	228	WP_002960575.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
DK181_RS10445 (DK182_10445)	-	2135990..2136931 (-)	942	WP_002959662.1	YitT family protein	-

Sequence

Protein

• Length: 853 a.a.
• Molecular weight: 95256.52 Da
• Isoelectric Point: 4.7979

>NTDB_id=253791 DK181_RS10415 WP_002960565.1 2129410..2131971(-) (hexA) [Streptococcus sobrinus strain SL1]
MAKDKISPGMQQYLDIKESYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLV
DLGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSSKPDSSNNFLVAIDYLNGVYGLSYMDLSTGEFCATSLTDFTA
VRSEIQNLKAKEVVLGFDLSDKQQEALTKQMSLLLSPEKEVYDDVQLIGSDLSSVEAQAAGKLLQYVHQTQKRELSHLQS
LVHYEIKDFLQMTYATKTSLDLLENARTSKKHGSLFWLLDSTKTAMGMRLLRTWIDRPLVSQEKILERQEIVQTFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLAQVPKIKTILASFSSPVLDRLNEAIDALPELESLIASAIDQ
DAPATITEGGMIKTGFDQQLDHYRQVMREGTTWIAEIEAKERSASGISTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERFGTAELAKIEGDMLEAREQSATLEYDIFMTVRNQVEKYIQRLQDLAKNIATVDALQSLAVVAENNHYVRPQFN
DQQLIDIQEGRHAVVEKVMGTQEYIPNTITLDQKTAIQLITGPNMSGKSTYMRQLALTVVMAQIGSFVAAESANLPIFDA
IYTRIGAADDLISGQSTFMVEMMEANMAIQRASSQSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTLFATHYHEL
TELSISLTHLVNVHVATLEKDGDVTFLHKITDGPADKSYGVHVAKIAGLPEALLQRANAILTDLEAHSVSLTGQEDFTEL
DKLVKQKRDSQQLSLFEVAEPNDKLVQALQDLDVVNMTPMEAMNALFELKKLL

Nucleotide

• Length: 2562 bp

>NTDB_id=253791 DK181_RS10415 WP_002960565.1 2129410..2131971(-) (hexA) [Streptococcus sobrinus strain SL1]
ATGGCAAAAGATAAAATTTCTCCAGGCATGCAGCAGTATTTAGACATCAAAGAATCCTATCCGGATGCTTTTTTGCTTTT
TCGGATGGGGGATTTTTATGAGCTCTTCTACGACGATGCGGTTAAGGCTGCTCAGATTTTGGAAATCAGCCTCACCAGTC
GCAATAAGAATGCTGACAATCCCATTCCTATGGCGGGCGTGCCCTATCATTCAGCACAACAATATATTGATGTCCTAGTC
GATTTGGGTTATAAGGTAGCCATTGCCGAGCAGATGGAGGACCCCAAAAAGGCTGTTGGTGTCGTCAAACGGGAGGTTGT
TCAGGTGATTACGCCAGGAACCGTGGTGGATTCCAGCAAGCCCGATAGCAGTAATAATTTCTTGGTTGCCATCGACTATC
TGAATGGGGTTTACGGACTCTCCTATATGGACCTCTCAACTGGGGAGTTTTGTGCCACCAGCCTGACAGACTTTACAGCC
GTTCGTAGCGAAATTCAAAATCTCAAGGCCAAGGAAGTCGTTCTGGGCTTTGATTTGAGTGACAAGCAGCAGGAAGCTCT
GACCAAGCAGATGAGTCTCCTTTTGTCACCTGAAAAAGAGGTCTATGATGATGTCCAGCTGATTGGCTCTGACTTGTCAA
GCGTAGAGGCCCAGGCCGCTGGTAAGCTCCTCCAATACGTCCATCAGACACAAAAGCGGGAGCTCAGCCACCTACAAAGT
CTGGTTCACTACGAAATCAAGGACTTCCTACAGATGACCTATGCCACCAAGACCAGTCTGGATCTCTTGGAAAATGCTAG
AACCAGCAAGAAACACGGCAGTCTCTTCTGGCTTTTGGATTCAACTAAGACAGCCATGGGGATGCGGCTCTTGCGGACCT
GGATTGATCGGCCCTTGGTTAGCCAAGAGAAAATCTTGGAGCGGCAGGAGATTGTTCAGACCTTCTTGGATAACTTTTTT
GAACGCAGCGACCTGACCGACAGCCTCAAGGGGGTCTACGATATTGAGCGCCTAGCCAGCCGAGTGTCTTTTGGTAAGGC
CAATCCCAAGGACCTCTTGCAGTTGGGGCATACTCTAGCCCAGGTTCCCAAAATCAAGACCATCTTAGCCAGCTTTTCTA
GTCCCGTTTTAGACCGGCTAAATGAAGCCATTGATGCCCTGCCGGAGTTGGAAAGTCTGATTGCCTCGGCCATTGACCAA
GATGCTCCAGCCACCATTACCGAAGGGGGCATGATTAAGACAGGCTTTGACCAGCAGTTGGATCATTATCGCCAGGTGAT
GCGGGAAGGAACCACCTGGATTGCCGAAATCGAAGCCAAGGAGCGATCAGCCAGCGGGATTTCCACCCTCAAGATTGATT
ACAACCGCAAGGATGGTTACTATTTCCATGTGACCAATTCCAATCTTTCCCTAGTGCCGGACCATTTCTTCCGCAAGGCA
ACTCTGAAAAATTCTGAGCGTTTTGGGACAGCGGAACTGGCTAAAATTGAAGGGGACATGCTGGAAGCCAGAGAGCAATC
GGCAACCCTGGAATACGATATTTTCATGACCGTCCGCAATCAGGTGGAAAAATACATCCAACGTCTGCAAGACCTGGCCA
AAAATATTGCAACTGTTGATGCCCTACAGAGCCTAGCCGTTGTGGCTGAAAACAATCACTATGTTCGGCCCCAGTTCAAC
GACCAGCAGCTTATTGATATTCAAGAGGGGCGCCACGCTGTTGTTGAGAAGGTTATGGGAACCCAGGAATACATTCCTAA
TACCATCACCTTGGATCAGAAGACTGCGATTCAGCTGATTACGGGTCCCAATATGAGCGGGAAATCCACTTATATGAGGC
AGTTGGCCCTGACTGTGGTCATGGCTCAAATCGGCTCCTTTGTGGCTGCCGAGTCTGCTAATCTTCCTATTTTTGATGCC
ATCTACACTCGGATTGGGGCAGCCGATGACCTGATTTCCGGGCAATCAACCTTTATGGTTGAGATGATGGAGGCCAATAT
GGCTATCCAGCGGGCTAGCAGTCAGTCCCTTATCCTCTTTGACGAATTGGGCCGAGGCACCGCCACCTATGACGGGATGG
CCCTGGCTCAGGCAATCATCGAATACATTCACGATAGGGTAGGTGCCAAGACCCTCTTTGCCACCCATTATCACGAATTG
ACGGAACTGTCAATCAGCTTGACACATCTGGTCAATGTCCACGTGGCGACTCTGGAGAAGGACGGCGATGTTACCTTCCT
GCATAAGATTACAGATGGTCCTGCTGACAAGTCTTACGGGGTCCATGTGGCCAAGATTGCAGGTTTGCCTGAGGCTCTCC
TCCAGCGAGCCAATGCTATCTTGACTGATTTAGAGGCCCATTCGGTCAGCTTGACCGGCCAAGAAGACTTTACGGAGCTT
GACAAACTTGTCAAACAGAAAAGAGACAGTCAACAGTTGTCCCTCTTTGAAGTAGCAGAACCTAATGATAAGTTGGTTCA
AGCCCTCCAAGACCTTGATGTGGTCAATATGACCCCTATGGAAGCCATGAATGCCCTCTTCGAATTGAAAAAATTATTGT
AA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	72.014	100	0.721
mutS	Pseudomonas stutzeri strain ATCC 17587	37.212	100	0.379