Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB/nlmE   Type   Regulator
Locus tag   DK181_RS04620 Genome accession   NZ_CP029490
Coordinates   962878..963651 (-) Length   257 a.a.
NCBI ID   WP_002961287.1    Uniprot ID   A0ABM6W599
Organism   Streptococcus sobrinus strain SL1     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 957878..968651
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK181_RS04600 (DK182_04600) - 958816..959345 (+) 530 Protein_861 YbaK/EbsC family protein -
  DK181_RS04605 (DK182_04605) - 960051..960554 (+) 504 WP_002961281.1 phosphatase PAP2 family protein -
  DK181_RS04610 (DK182_04610) comE/blpR 960668..961411 (+) 744 WP_002961283.1 response regulator transcription factor Regulator
  DK181_RS04615 (DK182_04615) - 961414..962760 (+) 1347 WP_002961285.1 sensor histidine kinase -
  DK181_RS04620 (DK182_04620) comB/nlmE 962878..963651 (-) 774 WP_002961287.1 HlyD family efflux transporter periplasmic adaptor subunit Regulator
  DK181_RS04625 (DK182_04625) comA/nlmT 963664..965811 (-) 2148 WP_002961290.1 peptide cleavage/export ABC transporter Regulator
  DK181_RS11055 (DK182_04630) - 966129..966344 (+) 216 WP_002961293.1 Blp family class II bacteriocin -
  DK181_RS04635 (DK182_04635) - 966994..967422 (+) 429 WP_002961294.1 hypothetical protein -
  DK181_RS04640 (DK182_04640) - 967492..967635 (+) 144 WP_028798426.1 hypothetical protein -
  DK181_RS04645 (DK182_04645) - 967661..968065 (+) 405 WP_028798427.1 hypothetical protein -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 29048.44 Da        Isoelectric Point: 10.0056

>NTDB_id=253739 DK181_RS04620 WP_002961287.1 962878..963651(-) (comB/nlmE) [Streptococcus sobrinus strain SL1]
MDKKLLSSSEFYRRRYQNFATLSVIPIALLVIYLIVFSMYATKEIVVTSTGELTPASNVTSIQSISDNAITTNNLRNNKT
VKKGDTLLKYEKTKLDSQTQLYLEETGQAIQEEKAPEVKATQDGILHLEKDYSGQKAIPNDTTIGEIYPNLQKEKAINLT
YYVNSNYIASIKTGQLARVSLKGDNNKNLLLKGKVIAIDKTATMTKEGNVFKVRARIDLEKQEKKYLKFGLQGKVTSIVA
RKTYFDYYKEKLLASFN

Nucleotide


Download         Length: 774 bp        

>NTDB_id=253739 DK181_RS04620 WP_002961287.1 962878..963651(-) (comB/nlmE) [Streptococcus sobrinus strain SL1]
ATGGATAAAAAATTACTGAGCAGTTCTGAATTTTACCGCAGGCGCTACCAAAATTTTGCGACCTTGTCGGTTATCCCAAT
AGCTTTACTGGTGATTTATCTTATTGTCTTTTCGATGTATGCGACCAAAGAAATTGTCGTTACCAGCACGGGTGAGTTGA
CACCAGCTTCAAATGTTACTTCTATCCAATCTATCAGTGATAATGCTATCACAACCAATAATTTACGAAACAATAAAACC
GTCAAAAAAGGCGACACCTTACTCAAATACGAAAAAACAAAATTAGATAGCCAAACCCAGCTCTACCTTGAAGAAACTGG
CCAGGCTATTCAAGAGGAAAAAGCTCCAGAAGTCAAGGCGACACAAGACGGCATCCTACATTTAGAAAAAGATTATAGCG
GTCAAAAAGCTATCCCAAACGACACGACTATCGGGGAAATTTATCCTAATCTTCAAAAGGAGAAAGCTATCAATCTCACT
TACTATGTCAACTCAAACTATATTGCTAGTATTAAGACTGGACAGTTGGCTAGAGTTAGCTTAAAAGGCGATAATAATAA
AAATCTCCTTCTCAAGGGAAAAGTGATTGCAATTGATAAAACAGCAACAATGACAAAAGAGGGCAATGTCTTTAAAGTAA
GGGCTAGAATAGACCTCGAAAAGCAAGAGAAAAAATATCTCAAATTCGGCCTCCAGGGCAAGGTGACTAGTATTGTTGCT
AGGAAGACCTACTTTGATTACTATAAGGAAAAGCTCCTAGCCTCATTCAACTAA

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(118-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB/nlmE Streptococcus mutans UA159

38.305

100

0.44

Multiple sequence alignment