Detailed information    

insolico Bioinformatically predicted

Overview

Name   spo0A   Type   Regulator
Locus tag   CS376_RS12630 Genome accession   NZ_CP024203
Coordinates   2571125..2571925 (-) Length   266 a.a.
NCBI ID   WP_003153177.1    Uniprot ID   I2C7K5
Organism   Bacillus velezensis strain NKG-1     
Function   activation and repression of comK; repression of rok; repression of abrB (predicted from homology)   
Competence regulation

Genomic Context

Location: 2566125..2576925
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CS376_RS12600 - 2566663..2567304 (+) 642 WP_099566897.1 helix-turn-helix domain-containing protein -
  CS376_RS21585 - 2567546..2567728 (+) 183 WP_169510260.1 hypothetical protein -
  CS376_RS12610 - 2567822..2568940 (+) 1119 WP_015240192.1 NADH-dependent flavin oxidoreductase -
  CS376_RS12615 - 2569068..2569280 (+) 213 WP_007408362.1 spore germination protein -
  CS376_RS12620 - 2569406..2569618 (+) 213 WP_003153181.1 spore germination protein -
  CS376_RS12625 alr 2569795..2570976 (+) 1182 WP_012117960.1 alanine racemase -
  CS376_RS12630 spo0A 2571125..2571925 (-) 801 WP_003153177.1 sporulation transcription factor Spo0A Regulator
  CS376_RS12635 spoIVB 2572206..2573486 (-) 1281 WP_099566898.1 SpoIVB peptidase -
  CS376_RS12640 recN 2573650..2575380 (-) 1731 WP_007408359.1 DNA repair protein RecN Machinery gene
  CS376_RS12645 ahrC 2575412..2575861 (-) 450 WP_003153173.1 transcriptional regulator AhrC/ArgR -
  CS376_RS12650 - 2575958..2576803 (-) 846 WP_099566899.1 TlyA family RNA methyltransferase -

Sequence

Protein


Download         Length: 266 a.a.        Molecular weight: 29630.11 Da        Isoelectric Point: 6.1630

>NTDB_id=252905 CS376_RS12630 WP_003153177.1 2571125..2571925(-) (spo0A) [Bacillus velezensis strain NKG-1]
MEKIKVCVADDNRELVSLLSEYIEGQDDMEVIGVAYNGQECLSLFKDKNPDVLVLDIIMPHLDGLAVLERLRESELEKQP
NVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLVGHIRQVSGNVSSVTHRAPSAQSSIIRSQPEPKRKNLDASITSII
HEIGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVS
MTKAKPTNSEFIAMVADKLRLEHKAS

Nucleotide


Download         Length: 801 bp        

>NTDB_id=252905 CS376_RS12630 WP_003153177.1 2571125..2571925(-) (spo0A) [Bacillus velezensis strain NKG-1]
GTGGAGAAAATTAAAGTTTGTGTTGCTGATGATAATCGAGAGCTTGTAAGCCTGTTGAGTGAATATATAGAGGGACAGGA
TGATATGGAAGTGATCGGCGTTGCTTATAACGGACAGGAATGTCTTTCTTTGTTTAAAGATAAGAATCCAGATGTGCTCG
TTTTAGACATTATCATGCCGCATCTGGACGGACTTGCGGTTTTGGAGCGTCTGCGGGAATCAGAGCTCGAGAAGCAGCCG
AACGTCATCATGCTGACGGCATTCGGTCAGGAAGACGTTACGAAAAAAGCCGTCGATTTAGGCGCGTCCTATTTCATCCT
GAAGCCGTTTGATATGGAAAACCTTGTCGGCCATATCCGCCAGGTAAGCGGAAATGTCAGCAGTGTCACACACCGTGCCC
CGTCTGCGCAAAGCAGCATTATCCGCAGCCAGCCTGAGCCGAAGCGGAAAAATCTCGATGCCAGCATTACAAGCATTATC
CATGAGATCGGTGTGCCTGCCCATATCAAAGGCTATCTTTATTTGCGTGAAGCCATTTCCATGGTGTATAACGATATTGA
ACTCCTCGGCAGCATCACAAAAGTCCTTTATCCCGACATCGCCAAAAAATTCAACACGACCGCAAGCCGTGTAGAACGGG
CCATCCGCCACGCCATTGAAGTCGCATGGAGCAGGGGAAATATTGATTCCATTTCTTCACTGTTCGGATATACGGTAAGC
ATGACAAAAGCAAAGCCAACCAACTCGGAATTCATCGCGATGGTTGCTGACAAGCTGAGATTAGAGCATAAAGCTTCGTA
A

Domains

Predicted by InterproScan.

Sporulation initiation factor Spo0A C terminal (Spo0A_C)

(156-259)

Response regulator receiver domain (Response_reg)

(6-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C7K5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  spo0A Bacillus subtilis subsp. subtilis str. 168

96.629

100

0.97

Multiple sequence alignment