Detailed information NTG0252873

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: CS376_RS00585
• Genome accession: NZ_CP024203
• Coordinates: 104113..106545 (+)
• Length: 810 a.a.
• NCBI ID: WP_015239036.1
• Uniprot ID: -
• Organism: Bacillus velezensis strain NKG-1
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 99113..111545

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CS376_RS00570	ctsR	101990..102454 (+)	465	WP_003156396.1	transcriptional regulator CtsR	-
CS376_RS00575	-	102468..103025 (+)	558	WP_007410387.1	UvrB/UvrC motif-containing protein	-
CS376_RS00580	-	103025..104116 (+)	1092	WP_003156398.1	protein arginine kinase	-
CS376_RS00585	clpC	104113..106545 (+)	2433	WP_015239036.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
CS376_RS00590	radA	106639..108018 (+)	1380	WP_014304212.1	DNA repair protein RadA	Machinery gene
CS376_RS00595	disA	108022..109104 (+)	1083	WP_007615225.1	DNA integrity scanning diadenylate cyclase DisA	-
CS376_RS00600	-	109218..110318 (+)	1101	WP_003156403.1	PIN/TRAM domain-containing protein	-
CS376_RS00605	ispD	110331..111029 (+)	699	WP_007410391.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
CS376_RS00610	ispF	111022..111498 (+)	477	WP_003156407.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 90040.49 Da
• Isoelectric Point: 5.9514

>NTDB_id=252873 CS376_RS00585 WP_015239036.1 104113..106545(+) (clpC) [Bacillus velezensis strain NKG-1]
MMFGRFTERAQKVLALAQEEALRLGHNNIGTEHILLGLVREGEGIAAKALQALGLGSDKIQKEVESLIGRGQEMSQTIHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNETGSSASGTNSNANT
PTLDSLARDLTAIAKEDSLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIINNEVPEILRDKRVM
TLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDEY
RKYIEKDAALERRFQPIQVDQPSADESIQILKGLRDRYEAHHRVSITDEAIEAAVKLSDRYISDRFLPDKAIDLIDEAGS
KVRLRSFTTPPNLKELEQKLDEVRKEKDAAVQSQEFEKAASLRDTEQRLREQVEDTKKTWKEKQGQENSEVSVEDIAMVV
SSWTGVPVSKIAQTETDKLLNMENILHSRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
SIFGDEEAMIRVDMSEYMEKHSTSRLVGSPPGYVGYDEGGQLTEKVRRKPYSVVLLDEIEKAHPDVFNILLQVLEDGRLT
DSKGRTVDFRNTILIMTSNVGASELKRNKYVGFNVQDESQNHKDMKDKVMGELKRAFRPEFINRIDEIIVFHSLEKKHLT
DIVSLMSDQLTKRLKEQDLSIELTDAAKAKVAEEGVDLEYGARPLRRAIQKHVEDRLSEELLRGNIDKGQHIVLDVEDGE
FVVKTTAKTN

Nucleotide

• Length: 2433 bp

>NTDB_id=252873 CS376_RS00585 WP_015239036.1 104113..106545(+) (clpC) [Bacillus velezensis strain NKG-1]
ATGATGTTTGGAAGGTTTACAGAGCGAGCTCAAAAGGTATTGGCACTGGCACAGGAAGAAGCACTGCGCTTAGGCCATAA
CAATATTGGAACTGAACATATCTTATTAGGTCTGGTTCGTGAAGGAGAAGGGATTGCGGCTAAAGCACTCCAAGCACTCG
GACTCGGTTCGGATAAAATTCAGAAAGAAGTGGAGAGCTTAATCGGACGGGGACAGGAAATGTCTCAAACGATTCATTAT
ACGCCAAGAGCAAAAAAAGTCATTGAGCTCAGCATGGATGAAGCCAGAAAGCTAGGACATTCTTATGTGGGAACAGAACA
CATACTTCTCGGACTGATTCGTGAAGGAGAAGGCGTAGCGGCGAGAGTTCTGAATAATCTCGGTGTCAGCTTGAATAAGG
CGAGACAGCAAGTGCTGCAGCTTCTGGGAAGCAATGAGACGGGATCTTCTGCATCCGGTACGAACAGCAATGCAAACACG
CCGACGCTGGACAGTCTGGCGCGTGATTTAACTGCGATTGCGAAGGAAGACAGTCTTGATCCGGTTATCGGCCGAAGCAA
AGAAATTCAGCGTGTTATTGAGGTATTAAGCCGCAGAACGAAGAATAACCCCGTTCTTATCGGAGAACCGGGTGTAGGTA
AAACTGCGATTGCTGAAGGCCTCGCACAGCAGATCATCAATAATGAAGTGCCGGAAATTTTACGTGATAAACGCGTAATG
ACATTAGACATGGGTACGGTTGTAGCCGGTACGAAATACCGCGGAGAATTTGAAGACCGCTTGAAAAAAGTAATGGATGA
AATACGTCAGGCCGGCAATATTATTTTATTCATTGACGAACTGCATACACTGATCGGAGCGGGGGGAGCAGAAGGTGCGA
TTGACGCGTCGAATATCTTAAAACCTTCACTGGCCCGCGGAGAGCTTCAATGCATCGGTGCGACAACGCTTGATGAATAC
CGTAAATATATCGAAAAAGACGCCGCTCTCGAGCGCCGTTTCCAGCCGATTCAGGTGGATCAGCCCTCAGCCGATGAAAG
CATTCAAATTTTAAAAGGGCTTCGTGACCGCTATGAAGCGCATCACCGCGTATCCATTACCGATGAAGCGATTGAAGCGG
CGGTAAAATTGTCCGACCGTTATATTTCTGACCGCTTCCTTCCGGATAAAGCGATCGATTTAATTGATGAAGCCGGTTCA
AAAGTGCGTCTCCGTTCGTTCACAACGCCTCCGAACTTAAAAGAGCTTGAGCAGAAACTCGATGAAGTTCGCAAGGAAAA
AGACGCTGCCGTTCAGAGCCAGGAGTTTGAAAAAGCGGCTTCCCTTCGTGATACGGAGCAGCGCCTGAGAGAACAGGTGG
AAGACACGAAAAAAACCTGGAAAGAAAAACAAGGCCAGGAGAACTCCGAAGTTTCTGTAGAGGATATCGCGATGGTTGTA
TCCAGCTGGACCGGGGTGCCTGTATCTAAAATTGCCCAAACGGAAACAGATAAGCTTCTCAATATGGAAAACATTCTGCA
CTCCCGCGTCATCGGCCAGGATGAAGCTGTTGTAGCCGTTGCAAAGGCCGTCAGACGTGCAAGAGCCGGTCTGAAGGACC
CGAAACGCCCGATTGGTTCATTCATCTTCCTAGGCCCTACAGGCGTTGGGAAGACAGAGCTGGCAAGAGCGCTGGCGGAA
TCCATTTTCGGTGATGAGGAAGCGATGATCAGAGTGGATATGTCCGAATACATGGAGAAACACTCGACTTCACGTCTTGT
CGGTTCTCCTCCGGGATATGTCGGCTATGATGAAGGCGGTCAGCTGACAGAAAAAGTGAGAAGAAAACCTTATTCTGTCG
TATTGCTTGATGAAATTGAAAAAGCGCATCCTGATGTGTTTAACATACTCCTGCAAGTGCTTGAAGACGGACGCTTGACT
GATTCAAAAGGACGCACTGTGGATTTCCGCAACACGATCCTGATTATGACGTCAAACGTCGGAGCGAGCGAGCTGAAACG
CAACAAATATGTGGGCTTCAATGTGCAGGATGAATCACAAAACCATAAAGACATGAAAGACAAAGTCATGGGAGAGCTGA
AGCGTGCCTTCAGACCTGAGTTTATCAACCGGATTGACGAAATTATCGTCTTCCACTCCCTTGAGAAAAAACACCTTACA
GACATCGTGTCGCTTATGTCTGATCAGTTAACAAAACGTCTGAAAGAACAAGATCTCTCTATCGAGCTGACGGATGCTGC
AAAAGCAAAAGTGGCAGAAGAGGGCGTCGATTTGGAATACGGCGCACGTCCGTTAAGAAGAGCGATTCAAAAGCATGTGG
AGGACCGGTTATCAGAAGAACTCCTCAGAGGCAATATTGATAAAGGCCAGCACATTGTTCTTGATGTTGAGGACGGCGAA
TTTGTCGTAAAAACAACTGCTAAAACGAACTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (536-708)

• AAA lid domain (AAA_lid_9) (343-444)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (714-793)

• ATPase family associated with various cellular activities (AAA) (AAA) (205-317)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-143)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	98.395	100	0.984
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.875	98.765	0.493
clpC	Streptococcus thermophilus LMD-9	46.723	100	0.475
clpC	Streptococcus thermophilus LMG 18311	46.481	100	0.473
clpC	Streptococcus pneumoniae Rx1	45.117	99.877	0.451
clpC	Streptococcus pneumoniae D39	45.117	99.877	0.451
clpC	Streptococcus mutans UA159	43.947	100	0.448
clpC	Streptococcus pneumoniae TIGR4	44.87	99.877	0.448
clpE	Streptococcus mutans UA159	53.313	80.123	0.427
clpC	Lactococcus lactis subsp. cremoris KW2	49.709	84.938	0.422
clpE	Streptococcus pneumoniae TIGR4	52.388	80.123	0.42
clpE	Streptococcus pneumoniae Rx1	52.388	80.123	0.42
clpE	Streptococcus pneumoniae D39	52.388	80.123	0.42
clpE	Streptococcus pneumoniae R6	52.388	80.123	0.42