Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   DG474_RS08175 Genome accession   NZ_CP029257
Coordinates   1700135..1702240 (-) Length   701 a.a.
NCBI ID   WP_255778048.1    Uniprot ID   -
Organism   Streptococcus oralis strain CCUG 53468     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1695135..1707240
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DG474_RS08155 (DG474_08285) - 1695696..1696085 (+) 390 Protein_1556 IS3 family transposase -
  DG474_RS08160 (DG474_08290) - 1696146..1697756 (-) 1611 WP_255778046.1 alpha-glucosidase -
  DG474_RS08165 (DG474_08295) - 1697909..1699393 (+) 1485 WP_255778047.1 DUF1846 domain-containing protein -
  DG474_RS08170 (DG474_08300) - 1699485..1699967 (+) 483 WP_000032556.1 S-ribosylhomocysteine lyase -
  DG474_RS08175 (DG474_08310) clpE 1700135..1702240 (-) 2106 WP_255778048.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DG474_RS08180 (DG474_08315) - 1702692..1706771 (-) 4080 WP_255778050.1 FctA domain-containing protein -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77481.22 Da        Isoelectric Point: 4.7134

>NTDB_id=252558 DG474_RS08175 WP_255778048.1 1700135..1702240(-) (clpE) [Streptococcus oralis strain CCUG 53468]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAQYRATGQLPGNAESDVQMQQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSIGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIEAEKDKQEKAVEAEDFEAALNAKTRIAELEKKVENHTEDMKVTASINDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLEHKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLNKEDLSKIVDLMLAEVNQTLAKKDIDLEVS
QAAKDFITEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDHLDAKHLEADMEDGGLVIREKA

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=252558 DG474_RS08175 WP_255778048.1 1700135..1702240(-) (clpE) [Streptococcus oralis strain CCUG 53468]
ATGAACAACAACTTTAATAACTTTAACAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATATAGTTC
TGAAAATCGTCGCTACTTGATTAATGGACGTGAAGTGACACCTGAGGAATTTGCTCAGTATCGTGCAACTGGTCAATTGC
CAGGAAATGCAGAATCTGATGTGCAAATGCAACAACAGGCTTCAGGTATGAAACAAGACGGTGTCCTTGCTAAACTAGGT
CGTAACTTGACCGCAGAAGCTCGTGAGGGCAAGCTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGTCGTACGAAAAATAATCCTGTTCTAGTCGGAGATGCAGGTGTTGGTAAGACAGCCGTTGTCGAAGGCC
TAGCACAAGCGATTGTGAACGGAGATGTTCCAGCTGCCATCAAGAACAAGGAAATTATTTCTATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGCAGCTTTGAAGAAAACGTTCAAAATCTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATCCTTGGTGCTGGTTCAATCGGTGGAGACAGTGGTTCTAAAGGTCTTGCAG
ATATTCTCAAGCCAGCTCTCTCTCGTGGTGAATTGACCGTTATTGGAGCGACAACTCAAGACGAATACCGTAACACCATC
TTGAAAAATGCAGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCAGCAGAGGATACCTTTAAAATCCT
TCAAGGGATTCGTGATCTCTATCAACAACACCACAATGTCATTTTGCCAGACGAAGTCTTGAAAGCAGCAGTGGATTATT
CTGTCCAATACATTCCTCAACGCAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACGGCAGCTCACTTGGCAGCT
CAACATCCTGTAACAGATGTGCATGCTGTTGAACGGGAAATTGAGGCAGAAAAAGACAAGCAAGAAAAAGCAGTTGAGGC
AGAAGACTTTGAAGCAGCTCTCAATGCTAAAACACGTATTGCAGAATTAGAGAAAAAAGTCGAAAACCACACAGAAGACA
TGAAAGTGACTGCAAGCATCAACGATGTGGCTGAGTCTGTAGAGCGAATGACAGGTATTCCAGTGTCACAAATGGGAGCG
TCAGATATCGAACGTTTGAAAGATATGGCTCATCGCTTGGAACACAAGGTAATCGGCCAAGATAAGGCAGTAGAAGCAGT
AGCTCGTGCTATCCGTCGTAACCGTGCAGGATTTGATGAGGGCAATCGCCCAATCGGTAGCTTCCTCTTTGTAGGGCCTA
CTGGGGTTGGTAAGACGGAACTTGCTAAGCAATTGGCGCTCGATATGTTTGGAACCAAGGATGCGATCATCCGTTTGGAT
ATGTCTGAATACAGTGACCGCACAGCCGTTTCTAAGTTAATTGGTACAACAGCAGGTTATGTAGGTTATGATGACAATAG
CAATACCTTGACAGAACGTGTTCGTCGCAATCCTTACTCTATCATTCTCTTGGATGAGATTGAAAAGGCTGATCCTCAAG
TAATCACCCTTCTCCTCCAAGTATTGGATGATGGTCGTTTGACTGATGGTCAAGGAAATACAGTGAACTTCAAGAACACG
GTCATTATCGCGACATCAAATGCTGGATTTGGTTATGAAGCCAACTTGACTGAAGATGCGGATAAACCAGAATTGATGGA
TCGTTTGAAACCATTCTTCCGCCCAGAGTTCCTTAACCGCTTTAACGCAGTTATCGAGTTCTCACACTTGAATAAGGAAG
ACCTTTCTAAGATTGTGGACTTGATGTTGGCGGAAGTCAACCAAACCTTGGCTAAGAAAGACATTGATTTGGAAGTCAGC
CAAGCAGCTAAGGACTTTATCACAGAAGAAGGCTATGACGAAGTCATGGGTGTTCGTCCTCTCCGTCGTGTGGTTGAACA
ACAAATTCGTGATAAGGTAACAGATTTCCACTTGGATCATCTAGATGCCAAACATTTGGAAGCAGATATGGAAGATGGTG
GTTTAGTTATTCGTGAAAAAGCCTAA

Domains

Predicted by InterProScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-680)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-603)

AAA lid domain (AAA_lid_9)

(259-354)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

48.069

99.715

0.479
  clpC Lactococcus lactis subsp. cremoris KW2

50.156

91.298

0.458
  clpE Streptococcus pneumoniae D39

48.826

91.155

0.445
  clpE Streptococcus pneumoniae R6

48.826

91.155

0.445
  clpE Streptococcus pneumoniae Rx1

48.826

91.155

0.445
  clpE Streptococcus pneumoniae TIGR4

48.746

91.013

0.444
  clpC Bacillus subtilis subsp. subtilis str. 168

45.146

92.582

0.418
  clpC Streptococcus pneumoniae Rx1

43.109

89.016

0.384
  clpC Streptococcus pneumoniae D39

43.109

89.016

0.384
  clpC Streptococcus pneumoniae TIGR4

42.949

89.016

0.382
  clpC Streptococcus thermophilus LMD-9

43.112

88.017

0.379
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.95

88.017

0.378
  clpC Streptococcus thermophilus LMG 18311

42.95

88.017

0.378
  clpC Streptococcus mutans UA159

42.071

88.16

0.371

Multiple sequence alignment