Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   DG474_RS04850 Genome accession   NZ_CP029257
Coordinates   986963..987427 (+) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus oralis strain CCUG 53468     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 981963..992427
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DG474_RS04815 (DG474_04915) - 982231..983145 (+) 915 WP_255778939.1 peptidase -
  DG474_RS04820 (DG474_04920) - 983272..983814 (+) 543 WP_255778940.1 ClbS/DfsB family four-helix bundle protein -
  DG474_RS04825 (DG474_04925) - 984110..984601 (+) 492 WP_255778962.1 hypothetical protein -
  DG474_RS04830 (DG474_04930) - 984688..985104 (+) 417 WP_000110625.1 immunity 70 family protein -
  DG474_RS04835 (DG474_04935) - 985171..985863 (+) 693 WP_255778941.1 YjjG family noncanonical pyrimidine nucleotidase -
  DG474_RS04840 (DG474_04940) - 985887..986180 (+) 294 WP_033629749.1 hypothetical protein -
  DG474_RS04845 (DG474_04945) - 986300..986953 (+) 654 WP_255778942.1 uracil-DNA glycosylase -
  DG474_RS04850 (DG474_04950) mutX 986963..987427 (+) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  DG474_RS04855 (DG474_04955) - 987440..988708 (+) 1269 WP_255778943.1 dihydroorotase -
  DG474_RS04860 (DG474_04960) - 988750..990090 (+) 1341 WP_255778944.1 MATE family efflux transporter -
  DG474_RS04865 (DG474_04965) - 990269..991237 (+) 969 WP_255778945.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  DG474_RS04870 (DG474_04970) - 991254..992246 (+) 993 WP_000448714.1 alpha-ketoacid dehydrogenase subunit beta -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=252526 DG474_RS04850 WP_001135768.1 986963..987427(+) (mutX) [Streptococcus oralis strain CCUG 53468]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=252526 DG474_RS04850 WP_001135768.1 986963..987427(+) (mutX) [Streptococcus oralis strain CCUG 53468]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAACGGAAAAGAACTGCTCATGCTCCATCGTAATAAGAAGCCTAATGA
TGTCCATGAAGGCAAATGGATTGGTGTGGGTGGTAAGCTAGAGCGAGGAGAGACACCTCAGGAATGCGCAGCGCGTGAAA
TCCTCGAAGAAACAGGGCTCAAAGCCAAGCCAGTACTTAAAGGTGTTATCACTTTTCCTGAATTTACGCCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACAGAGTTCGAGGGTGACTTGATTGACTGCAATGAGGGGACCTTAGAATGGGTTCC
CTATGATGAAGTCTTAAGCAAGCCAACTTGGGAGGGTGATCACACCTTTGTTGAGTGGCTTTTAGAGGACAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987