Detailed information NTG0252401

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: CR542_RS08555
• Genome accession: NZ_CP024126
• Coordinates: 1671695..1672744 (-)
• Length: 349 a.a.
• NCBI ID: WP_009910567.1
• Uniprot ID: A0A7Y6RPS3
• Organism: Streptococcus suis strain HA0609
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1666695..1677744

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CR542_RS08535 (CR542_08520)	nadE	1667523..1668347 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
CR542_RS08540 (CR542_08525)	-	1669221..1669748 (-)	528	WP_004194600.1	VanZ family protein	-
CR542_RS08545 (CR542_08530)	rlmN	1669745..1670857 (-)	1113	WP_004194597.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
CR542_RS08550 (CR542_08535)	-	1670866..1671507 (-)	642	WP_004194595.1	YutD family protein	-
CR542_RS08555 (CR542_08540)	sepM	1671695..1672744 (-)	1050	WP_009910567.1	SepM family pheromone-processing serine protease	Regulator
CR542_RS08560 (CR542_08545)	coaD	1672731..1673219 (-)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
CR542_RS08565 (CR542_08550)	rsmD	1673209..1673748 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
CR542_RS08570 (CR542_08555)	-	1674047..1674769 (-)	723	WP_013730502.1	hypothetical protein	-
CR542_RS08575 (CR542_08560)	-	1674826..1675212 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
CR542_RS08580 (CR542_08565)	-	1675212..1675430 (-)	219	WP_004194736.1	YqgQ family protein	-
CR542_RS08585 (CR542_08570)	-	1675730..1676332 (-)	603	WP_004194738.1	response regulator transcription factor	-
CR542_RS08590 (CR542_08575)	-	1676329..1677423 (-)	1095	WP_024394990.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37733.77 Da
• Isoelectric Point: 4.6112

>NTDB_id=252401 CR542_RS08555 WP_009910567.1 1671695..1672744(-) (sepM) [Streptococcus suis strain HA0609]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLVKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=252401 CR542_RS08555 WP_009910567.1 1671695..1672744(-) (sepM) [Streptococcus suis strain HA0609]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGGTTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTATCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATTTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A7Y6RPS3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.519	99.427	0.602