Detailed information NTG0251546

Bioinformatically predicted

Overview

• Name: comB6
• Type: Machinery gene
• Locus tag: BXP22_RS07585
• Genome accession: NZ_CP024072
• Coordinates: 1554599..1555654 (-)
• Length: 351 a.a.
• NCBI ID: WP_000786677.1
• Uniprot ID: D7FG37
• Organism: Helicobacter pylori strain 7.13_R1b
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1549599..1560654

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BXP22_RS07560 (BXP22_07555)	-	1550136..1551548 (-)	1413	WP_001861341.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-
BXP22_RS07565 (BXP22_07560)	comB10	1551618..1552754 (-)	1137	WP_001045869.1	DNA type IV secretion system protein ComB10	Machinery gene
BXP22_RS07570 (BXP22_07565)	comB9	1552747..1553730 (-)	984	WP_001861340.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
BXP22_RS07575 (BXP22_07570)	comB8	1553730..1554473 (-)	744	WP_000660520.1	type IV secretion system protein	Machinery gene
BXP22_RS07580 (BXP22_07575)	comB7	1554470..1554583 (-)	114	WP_001217873.1	hypothetical protein	Machinery gene
BXP22_RS07585 (BXP22_07580)	comB6	1554599..1555654 (-)	1056	WP_000786677.1	P-type conjugative transfer protein TrbL	Machinery gene
BXP22_RS07590 (BXP22_07585)	-	1555662..1556657 (-)	996	WP_000468428.1	PDZ domain-containing protein	-
BXP22_RS07595 (BXP22_07590)	-	1556657..1556959 (-)	303	WP_000347926.1	YbaB/EbfC family nucleoid-associated protein	-
BXP22_RS07600 (BXP22_07595)	panD	1556962..1557315 (-)	354	WP_000142236.1	aspartate 1-decarboxylase	-
BXP22_RS07605 (BXP22_07600)	-	1557305..1559530 (-)	2226	WP_001051506.1	AAA family ATPase	-
BXP22_RS07610 (BXP22_07605)	-	1559530..1559805 (-)	276	WP_000784899.1	ATP-dependent Clp protease adaptor ClpS	-
BXP22_RS07615 (BXP22_07610)	-	1559820..1560233 (-)	414	WP_001023005.1	universal stress protein	-

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 39908.89 Da
• Isoelectric Point: 8.5786

>NTDB_id=251546 BXP22_RS07585 WP_000786677.1 1554599..1555654(-) (comB6) [Helicobacter pylori strain 7.13_R1b]
MKNDAYEIILSWFITPLTAILGRFAEFFLYTLHAQLVFNSVVALAFMLFAYRSLKEQNFFSASALTEALWFVGFFALFNY
ALKNPMHFYEFFQNAIFIAPNMIAQSLSQSLSNFSNHALSLDFIFNHGFYALSFISDLSHNEMSVWLFLSILQGLFLSVL
FAIIILVYLEVHVWCSLGVLFLAFGFFKTWRSVVVICLKKCFALGFYKPFLLLVGFLNVSVTKALIDAHMQEKQDLSLLL
VVALFLCCVFIIGVPFFINALFRVQNSLKETYKLATNLSANLSQNALNSLQYITTPPAPSSVSSSMNESVSKEKETHSPT
FKVETTQLDVKIPNFKQKKVKKDTINTKNEI

Nucleotide

• Length: 1056 bp

>NTDB_id=251546 BXP22_RS07585 WP_000786677.1 1554599..1555654(-) (comB6) [Helicobacter pylori strain 7.13_R1b]
ATGAAAAATGACGCTTATGAGATTATTCTTTCTTGGTTTATCACGCCTCTCACGGCGATTTTAGGGCGTTTCGCTGAATT
TTTTCTCTACACTTTGCATGCGCAATTGGTGTTTAATAGCGTGGTCGCTTTGGCGTTCATGCTTTTTGCTTACAGGAGCT
TGAAGGAACAGAATTTCTTCAGCGCCAGCGCACTAACAGAAGCGTTATGGTTTGTGGGGTTTTTTGCGCTGTTTAACTAC
GCTTTAAAAAATCCCATGCATTTTTATGAATTTTTCCAAAACGCTATTTTTATTGCGCCTAACATGATCGCGCAGAGCCT
CTCTCAAAGCTTGAGTAACTTTTCTAACCACGCGCTTTCTTTAGATTTTATCTTTAATCATGGTTTTTATGCCCTTAGTT
TTATCAGCGATTTGAGCCATAATGAAATGTCTGTGTGGCTTTTTTTAAGCATTTTGCAAGGGCTTTTTTTGAGCGTGCTG
TTTGCGATCATCATTTTAGTGTATTTAGAAGTGCATGTGTGGTGCTCTTTAGGGGTGCTGTTTTTAGCGTTTGGGTTTTT
CAAAACCTGGAGGAGCGTTGTGGTTATATGCCTAAAAAAATGCTTCGCTCTTGGGTTTTACAAGCCTTTTTTGTTGTTGG
TGGGGTTTTTGAATGTGTCGGTTACTAAGGCTTTAATAGACGCTCATATGCAAGAAAAACAAGATTTAAGCCTTTTATTG
GTGGTAGCGTTATTTTTGTGTTGCGTTTTTATCATAGGCGTGCCTTTTTTCATCAACGCTTTGTTTAGGGTGCAAAACAG
CCTTAAAGAAACTTACAAACTCGCCACCAATTTGAGCGCTAACCTCAGCCAAAACGCCCTTAATTCCTTACAATATATCA
CGACCCCACCCGCTCCCTCTAGCGTTTCTTCTTCTATGAATGAAAGCGTCTCTAAAGAAAAAGAAACGCATTCCCCCACT
TTTAAGGTAGAAACCACTCAATTAGATGTAAAAATCCCAAATTTCAAGCAAAAAAAGGTTAAAAAGGATACAATAAATAC
AAAAAATGAAATTTAA

Domains

Predicted by InterproScan.

• TrbL/VirB6 plasmid conjugal transfer protein (TrbL) (44-254)

3D structure

• AlphaFold DB: D7FG37

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB6	Helicobacter pylori 26695	98.575	100	0.986