Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   BXP22_RS07575 Genome accession   NZ_CP024072
Coordinates   1553730..1554473 (-) Length   247 a.a.
NCBI ID   WP_000660520.1    Uniprot ID   D7FG35
Organism   Helicobacter pylori strain 7.13_R1b     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1548730..1559473
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BXP22_RS07555 (BXP22_07550) gmd 1548963..1550108 (-) 1146 WP_000659801.1 GDP-mannose 4,6-dehydratase -
  BXP22_RS07560 (BXP22_07555) - 1550136..1551548 (-) 1413 WP_001861341.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  BXP22_RS07565 (BXP22_07560) comB10 1551618..1552754 (-) 1137 WP_001045869.1 DNA type IV secretion system protein ComB10 Machinery gene
  BXP22_RS07570 (BXP22_07565) comB9 1552747..1553730 (-) 984 WP_001861340.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  BXP22_RS07575 (BXP22_07570) comB8 1553730..1554473 (-) 744 WP_000660520.1 type IV secretion system protein Machinery gene
  BXP22_RS07580 (BXP22_07575) comB7 1554470..1554583 (-) 114 WP_001217873.1 hypothetical protein Machinery gene
  BXP22_RS07585 (BXP22_07580) comB6 1554599..1555654 (-) 1056 WP_000786677.1 P-type conjugative transfer protein TrbL Machinery gene
  BXP22_RS07590 (BXP22_07585) - 1555662..1556657 (-) 996 WP_000468428.1 PDZ domain-containing protein -
  BXP22_RS07595 (BXP22_07590) - 1556657..1556959 (-) 303 WP_000347926.1 YbaB/EbfC family nucleoid-associated protein -
  BXP22_RS07600 (BXP22_07595) panD 1556962..1557315 (-) 354 WP_000142236.1 aspartate 1-decarboxylase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28737.96 Da        Isoelectric Point: 8.9546

>NTDB_id=251544 BXP22_RS07575 WP_000660520.1 1553730..1554473(-) (comB8) [Helicobacter pylori strain 7.13_R1b]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRND

Nucleotide


Download         Length: 744 bp        

>NTDB_id=251544 BXP22_RS07575 WP_000660520.1 1553730..1554473(-) (comB8) [Helicobacter pylori strain 7.13_R1b]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTCAGATTGGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGATGATAAATCGCGCT
ATGAATTGGTGCGTTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCTATTGCGGCTAAACTTTTGAATGAAAACAAGCTCGTGTATGAAAAGCGTTATAAAATCGTATTGAGCTATTTGTTTG
ACACTCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAACAGGAATGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D7FG35

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.571

100

0.976

Multiple sequence alignment