Detailed information NTG0251442

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: CR541_RS08385
• Genome accession: NZ_CP024050
• Coordinates: 1637102..1638151 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain CS100322
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1632102..1643151

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CR541_RS08365 (CR541_08320)	nadE	1632508..1633332 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
CR541_RS08370 (CR541_08325)	-	1634628..1635155 (-)	528	WP_012027591.1	VanZ family protein	-
CR541_RS08375 (CR541_08330)	rlmN	1635152..1636264 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
CR541_RS08380 (CR541_08335)	-	1636273..1636914 (-)	642	WP_012027595.1	YutD family protein	-
CR541_RS08385 (CR541_08340)	sepM	1637102..1638151 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
CR541_RS08390 (CR541_08345)	coaD	1638138..1638626 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
CR541_RS08395 (CR541_08350)	rsmD	1638616..1639155 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
CR541_RS08400 (CR541_08355)	-	1639463..1640185 (-)	723	WP_012027598.1	lipoprotein	-
CR541_RS08405 (CR541_08360)	-	1640242..1640628 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
CR541_RS08410 (CR541_08365)	-	1640628..1640846 (-)	219	WP_004194736.1	YqgQ family protein	-
CR541_RS08415 (CR541_08370)	-	1641154..1641756 (-)	603	WP_012027601.1	response regulator transcription factor	-
CR541_RS08420 (CR541_08375)	-	1641753..1642847 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=251442 CR541_RS08385 WP_012775295.1 1637102..1638151(-) (sepM) [Streptococcus suis strain CS100322]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=251442 CR541_RS08385 WP_012775295.1 1637102..1638151(-) (sepM) [Streptococcus suis strain CS100322]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605