Detailed information    

insolico Bioinformatically predicted

Overview

Name   waaF   Type   Regulator
Locus tag   CRM98_RS06340 Genome accession   NZ_CP023867
Coordinates   1194992..1195951 (-) Length   319 a.a.
NCBI ID   WP_002852903.1    Uniprot ID   A0A5Y6P8U5
Organism   Campylobacter jejuni strain FDAARGOS_422     
Function   repress natural transformation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1185655..1211636 1194992..1195951 within 0


Gene organization within MGE regions


Location: 1185655..1211636
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CRM98_RS06295 (CRM98_06295) dnaX 1185655..1187184 (-) 1530 WP_002852689.1 DNA polymerase III subunit gamma/tau -
  CRM98_RS06300 (CRM98_06300) rho 1187188..1188486 (-) 1299 WP_002852852.1 transcription termination factor Rho -
  CRM98_RS06305 (CRM98_06305) - 1188595..1190952 (+) 2358 WP_079254439.1 heavy metal translocating P-type ATPase -
  CRM98_RS06310 (CRM98_06310) ccoS 1190949..1191155 (+) 207 WP_002852798.1 cbb3-type cytochrome oxidase assembly protein CcoS -
  CRM98_RS06315 (CRM98_06315) - 1191178..1191480 (-) 303 WP_002852762.1 cytochrome c -
  CRM98_RS06320 (CRM98_06320) gmhB 1191562..1192122 (+) 561 WP_002878815.1 D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase -
  CRM98_RS06325 (CRM98_06325) rfaD 1192123..1193076 (+) 954 WP_002852832.1 ADP-glyceromanno-heptose 6-epimerase -
  CRM98_RS06330 (CRM98_06330) rfaE1 1193069..1194454 (+) 1386 WP_002852777.1 D-glycero-beta-D-manno-heptose-7-phosphate kinase -
  CRM98_RS06335 (CRM98_06335) gmhA 1194451..1195011 (+) 561 WP_002852775.1 D-sedoheptulose 7-phosphate isomerase -
  CRM98_RS06340 (CRM98_06340) waaF 1194992..1195951 (-) 960 WP_002852903.1 lipopolysaccharide heptosyltransferase II Regulator
  CRM98_RS06345 (CRM98_06345) - 1196010..1196822 (+) 813 WP_002852816.1 glycosyltransferase family 2 protein -
  CRM98_RS09085 - 1196814..1197155 (-) 342 WP_002852868.1 hypothetical protein -
  CRM98_RS09090 - 1197200..1197646 (-) 447 WP_002852791.1 hypothetical protein -
  CRM98_RS06355 (CRM98_06355) - 1197634..1198299 (-) 666 WP_002852731.1 acylneuraminate cytidylyltransferase family protein -
  CRM98_RS06360 (CRM98_06360) neuC 1198296..1199414 (-) 1119 WP_002852786.1 UDP-N-acetylglucosamine 2-epimerase -
  CRM98_RS06365 (CRM98_06365) neuB 1199411..1200451 (-) 1041 WP_002852665.1 N-acetylneuraminate synthase -
  CRM98_RS06370 (CRM98_06370) - 1200452..1201327 (-) 876 WP_002852706.1 alpha-2,3-sialyltransferase -
  CRM98_RS06375 (CRM98_06375) - 1201416..1202321 (+) 906 WP_002852740.1 glycosyltransferase family 2 protein -
  CRM98_RS06380 (CRM98_06380) - 1202307..1203350 (-) 1044 WP_032595791.1 beta-1,4-N-acetylgalactosaminyltransferase -
  CRM98_RS06385 (CRM98_06385) - 1203420..1204589 (-) 1170 WP_002852863.1 glycosyltransferase family 2 protein -
  CRM98_RS06390 (CRM98_06390) - 1204593..1206141 (-) 1549 Protein_1224 glycosyltransferase -
  CRM98_RS06395 (CRM98_06395) htrB 1206138..1207025 (-) 888 WP_002852805.1 lipid A biosynthesis lauroyl acyltransferase HtrB -
  CRM98_RS06400 (CRM98_06400) waaC 1207015..1208043 (-) 1029 WP_002852873.1 lipopolysaccharide heptosyltransferase I -
  CRM98_RS06405 (CRM98_06405) - 1208110..1208904 (+) 795 WP_002852820.1 3'-5' exonuclease -
  CRM98_RS06410 (CRM98_06410) galE 1208962..1209948 (+) 987 WP_002852683.1 UDP-glucose 4-epimerase GalE -
  CRM98_RS06415 (CRM98_06415) pglK 1209942..1211636 (+) 1695 WP_002858308.1 ABC-type lipopolysaccharide transporter PglK -

Sequence

Protein


Download         Length: 319 a.a.        Molecular weight: 36766.44 Da        Isoelectric Point: 10.4054

>NTDB_id=250747 CRM98_RS06340 WP_002852903.1 1194992..1195951(-) (waaF) [Campylobacter jejuni strain FDAARGOS_422]
MKIFIHLPTWLGDAVMASPALYTIKEHFKNAQFILYGSLVSTALFKEFPNSKIIIENKQSRYKQALSLRKKLGKIDFSFA
FRSAFSSKIILHILKTKQRYFFDKNKYKEEHQVLKYLYFIENSLSIKAHFKDLKLPFKLKFQNPLVLKNGKKILGLNPGA
SFGSAKRWDASYFAKVALNFSQSHEILIFGAGKAEQELCNEIYQILKEQNIKVKNLCNKTTIKTLCQNIAFCDLFITNDS
GPMHLSAVYKVKTVAIFGPTKFTQTSPWQNQNAKLVHLDLACMPCMQKICPLKHHKCMKDLKPQRVIEEARNLLKNPHL

Nucleotide


Download         Length: 960 bp        

>NTDB_id=250747 CRM98_RS06340 WP_002852903.1 1194992..1195951(-) (waaF) [Campylobacter jejuni strain FDAARGOS_422]
ATGAAAATTTTTATACACCTTCCCACTTGGCTAGGCGATGCGGTGATGGCTTCACCTGCTTTATACACCATAAAAGAACA
TTTTAAAAATGCTCAGTTTATCCTTTATGGATCTTTGGTTTCCACAGCACTTTTTAAAGAATTTCCTAATTCTAAAATCA
TCATAGAAAATAAACAATCCCGCTATAAACAAGCCCTATCTTTACGCAAAAAACTTGGTAAAATCGATTTTAGCTTTGCT
TTTAGATCTGCGTTTTCTTCTAAGATTATCTTGCATATTCTTAAAACAAAACAAAGATATTTTTTTGACAAAAACAAGTA
CAAAGAAGAACATCAAGTTTTAAAATACCTTTATTTTATAGAAAACTCACTTAGTATAAAAGCTCATTTTAAAGACTTAA
AACTTCCCTTTAAGCTAAAATTTCAAAACCCTCTTGTCTTAAAAAATGGCAAAAAAATTCTAGGACTCAACCCTGGCGCA
AGCTTTGGAAGTGCAAAAAGATGGGATGCGAGTTATTTTGCTAAAGTGGCTTTAAATTTCAGCCAAAGTCATGAGATTTT
AATCTTTGGTGCAGGAAAAGCCGAACAAGAACTTTGTAATGAAATTTATCAAATTTTAAAAGAACAAAACATAAAAGTAA
AAAATCTTTGCAATAAAACCACCATCAAAACCCTTTGTCAAAATATCGCTTTTTGCGATCTTTTCATCACAAATGACAGT
GGTCCTATGCACCTAAGTGCGGTTTATAAGGTAAAAACCGTAGCTATTTTTGGCCCCACAAAATTTACCCAAACTTCACC
TTGGCAAAATCAAAACGCAAAATTAGTACACTTAGATCTAGCTTGTATGCCTTGTATGCAAAAAATCTGCCCTTTAAAAC
ACCACAAATGCATGAAAGATTTAAAGCCTCAAAGGGTTATAGAAGAAGCTAGAAATTTACTTAAAAACCCTCATCTATAA

Domains

Predicted by InterproScan.

Glycosyltransferase family 9 (heptosyltransferase) (Glyco_transf_9)

(96-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5Y6P8U5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  waaF Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

94.984

100

0.95

Multiple sequence alignment