Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CRH11_RS11210 Genome accession   NZ_CP023859
Coordinates   2154834..2155490 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain L-1     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2149834..2160490
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CRH11_RS11185 (CRH11_11180) oppF 2150363..2151280 (+) 918 WP_015239568.1 oligopeptide ABC transporter ATP-binding protein OppF -
  CRH11_RS11190 (CRH11_11185) - 2151387..2152574 (+) 1188 WP_015239569.1 putative glycoside hydrolase -
  CRH11_RS11195 (CRH11_11190) - 2152692..2153270 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  CRH11_RS11200 (CRH11_11195) spx 2153449..2153844 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  CRH11_RS11205 (CRH11_11200) - 2153902..2154558 (-) 657 WP_015239570.1 TerC family protein -
  CRH11_RS11210 (CRH11_11205) mecA 2154834..2155490 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  CRH11_RS11215 (CRH11_11210) - 2155641..2156801 (+) 1161 WP_069006905.1 competence protein CoiA family protein -
  CRH11_RS11220 (CRH11_11215) pepF 2157029..2158858 (+) 1830 WP_094031915.1 oligoendopeptidase F Regulator
  CRH11_RS20800 (CRH11_11220) - 2158896..2159063 (-) 168 WP_003155026.1 hypothetical protein -
  CRH11_RS11230 (CRH11_11225) spxH 2159349..2160251 (-) 903 WP_032874464.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=250562 CRH11_RS11210 WP_003155032.1 2154834..2155490(+) (mecA) [Bacillus velezensis strain L-1]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=250562 CRH11_RS11210 WP_003155032.1 2154834..2155490(+) (mecA) [Bacillus velezensis strain L-1]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGATGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment