Detailed information NTG0250529

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: CRH11_RS02395
• Genome accession: NZ_CP023859
• Coordinates: 456525..457688 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain L-1
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 451525..462688

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CRH11_RS02365 (CRH11_02365)	-	451789..452208 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
CRH11_RS02370 (CRH11_02370)	comFC	452282..452971 (-)	690	WP_197200179.1	phosphoribosyltransferase family protein	Machinery gene
CRH11_RS02375 (CRH11_02375)	-	452977..453261 (-)	285	WP_007407481.1	late competence development ComFB family protein	-
CRH11_RS02380 (CRH11_02380)	comFA	453319..454704 (-)	1386	WP_099320008.1	DEAD/DEAH box helicase	Machinery gene
CRH11_RS02385 (CRH11_02385)	-	454813..455661 (-)	849	WP_094031329.1	DegV family protein	-
CRH11_RS02390 (CRH11_02390)	degU	455759..456448 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
CRH11_RS02395 (CRH11_02395)	degS	456525..457688 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
CRH11_RS02400 (CRH11_02400)	-	457911..458558 (+)	648	WP_007407485.1	YigZ family protein	-
CRH11_RS02405 (CRH11_02405)	-	458563..459798 (+)	1236	WP_025285355.1	LCP family protein	-
CRH11_RS02410 (CRH11_02410)	-	459897..460973 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
CRH11_RS02415 (CRH11_02415)	tuaH	461106..462302 (-)	1197	WP_094031330.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=250529 CRH11_RS02395 WP_007407484.1 456525..457688(-) (degS) [Bacillus velezensis strain L-1]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=250529 CRH11_RS02395 WP_007407484.1 456525..457688(-) (degS) [Bacillus velezensis strain L-1]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951