Detailed information NTG0024999

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: GBAA_RS21355
• Genome accession: NC_007530
• Coordinates: 4009078..4009872 (-)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus anthracis str. 'Ames Ancestor'
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 4004078..4014872

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GBAA_RS21335 (GBAA4390)	-	4005879..4006112 (+)	234	WP_001190187.1	DUF2627 domain-containing protein	-
GBAA_RS21340 (GBAA4391)	-	4006161..4006889 (-)	729	WP_000172562.1	glycerophosphodiester phosphodiesterase	-
GBAA_RS21345 (GBAA4392)	-	4006940..4007086 (+)	147	WP_001247671.1	YycC family protein	-
GBAA_RS21350 (GBAA4393)	-	4007254..4008780 (-)	1527	WP_000218387.1	glycosyltransferase family 39 protein	-
GBAA_RS21355 (GBAA4394)	spo0A	4009078..4009872 (-)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
GBAA_RS21365 (GBAA4396)	spoIVB	4010160..4011458 (-)	1299	WP_002037056.1	SpoIVB peptidase	-
GBAA_RS21370 (GBAA4397)	recN	4011577..4013316 (-)	1740	WP_000947756.1	DNA repair protein RecN	Machinery gene
GBAA_RS21375 (GBAA4398)	argR	4013584..4014033 (-)	450	WP_001032581.1	arginine repressor ArgR	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=24999 GBAA_RS21355 WP_003161566.1 4009078..4009872(-) (spo0A) [Bacillus anthracis str. 'Ames Ancestor']
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=24999 GBAA_RS21355 WP_003161566.1 4009078..4009872(-) (spo0A) [Bacillus anthracis str. 'Ames Ancestor']
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCAAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCCGAGTTTATTGCAATGGTTGCGGATAAGCTTAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818