Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   CRD75_RS06170 Genome accession   NZ_CP023769
Coordinates   1209907..1210944 (-) Length   345 a.a.
NCBI ID   WP_011284961.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain HarveyGAS     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1204907..1215944
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CRD75_RS06150 (CRD75_06150) - 1205656..1206282 (+) 627 WP_002983834.1 A24 family peptidase -
  CRD75_RS06155 (CRD75_06155) rlmN 1206364..1207443 (-) 1080 WP_002992788.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  CRD75_RS06160 (CRD75_06160) - 1207447..1208067 (-) 621 WP_002992791.1 YutD family protein -
  CRD75_RS06165 (CRD75_06165) - 1208515..1209492 (-) 978 WP_021341005.1 LacI family DNA-binding transcriptional regulator -
  CRD75_RS06170 (CRD75_06170) sepM 1209907..1210944 (-) 1038 WP_011284961.1 SepM family pheromone-processing serine protease Regulator
  CRD75_RS06175 (CRD75_06175) coaD 1210931..1211422 (-) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  CRD75_RS06180 (CRD75_06180) rsmD 1211412..1211951 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  CRD75_RS06185 (CRD75_06185) asnA 1212074..1213066 (-) 993 WP_002983817.1 aspartate--ammonia ligase -
  CRD75_RS06190 (CRD75_06190) arcC 1213379..1214329 (-) 951 WP_009880962.1 carbamate kinase -
  CRD75_RS06195 (CRD75_06195) - 1214349..1215680 (-) 1332 WP_011284962.1 dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37571.27 Da        Isoelectric Point: 9.6692

>NTDB_id=249843 CRD75_RS06170 WP_011284961.1 1209907..1210944(-) (sepM) [Streptococcus pyogenes strain HarveyGAS]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDTDFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=249843 CRD75_RS06170 WP_011284961.1 1209907..1210944(-) (sepM) [Streptococcus pyogenes strain HarveyGAS]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCGCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATACTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.986

100

0.69

Multiple sequence alignment