Detailed information NTG0248927

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: A1552VC_RS02395
• Genome accession: NZ_CP028894
• Coordinates: 487553..490126 (+)
• Length: 857 a.a.
• NCBI ID: WP_001235051.1
• Uniprot ID: Q9KU18
• Organism: Vibrio cholerae strain A1552
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 482553..495126

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A1552VC_RS02370 (A1552VC_00468)	pheA	482706..483881 (-)	1176	WP_000130282.1	prephenate dehydratase	-
A1552VC_RS02375 (A1552VC_00470)	raiA	484121..484447 (-)	327	WP_000700176.1	ribosome-associated translation inhibitor RaiA	-
A1552VC_RS02380 (A1552VC_00471)	comL	484849..485574 (-)	726	WP_000877198.1	outer membrane protein assembly factor BamD	Machinery gene
A1552VC_RS02385 (A1552VC_00472)	rluD	485729..486703 (+)	975	WP_000941107.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
A1552VC_RS02390 (A1552VC_00473)	pgeF	486706..487428 (+)	723	WP_000602844.1	peptidoglycan editing factor PgeF	-
A1552VC_RS02395 (A1552VC_00474)	clpC	487553..490126 (+)	2574	WP_001235051.1	ATP-dependent chaperone ClpB	Regulator

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 95827.76 Da
• Isoelectric Point: 5.3574

>NTDB_id=248927 A1552VC_RS02395 WP_001235051.1 487553..490126(+) (clpC) [Vibrio cholerae strain A1552]
MRLDRFTSKFQIAISDAQSLALGRDHQYIEPVHLMVALLDQNGSPIRPLLTMLNVDVMQLRSKLGEMLDRLPKVSGIGGD
VQLSSALGSLFNLCDKVAQKRQDAYISSEIYLLAAIEDKGPLGHLLKEFGLTEKKVSEAIEKIRGGQKVNDPNAEELRQA
LEKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVIIGEPGVGKTAIVEGLAQRIINNEVPEGLRGRRVLSL
DMGALVAGAKYRGEFEERLKSVLNELAKEEGNIILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDPALERRFQKVLVDEPTVEDTIAILRGLKERYELHHHVEITDPAIVAAASLSHRYISDRQLPDKAIDLIDEAASS
IRMQIDSKPEALDKLERKIIQLKIEQQALSNEHDEASEKRLAILNEELQEKERDYAELEEVWKAEKAALSGTQHIKAALE
QARMDLEVARRAGDLNRMSELQYGRIPELEKQLDLAAQAEMQEMTLLRNKVTDAEIAEVLSKQTGIPVSKMLEAEKEKLL
RMEDVLHKRVIGQKEAVEVVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLANFLFDSEDAMVRVDMSEFMEK
HSVARLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSSRIQENFARLDYQGIKEQVMDVVSKHFRPEFLNRVDESVVFHPLGQEHIKSIASIQLARLRQRLAERDYQLEVDDEAL
DLIAHVGFDPVYGARPLKRAIQQNVENPLAKSILAGKFLPGSPILLSVKDGNIFASQ

Nucleotide

• Length: 2574 bp

>NTDB_id=248927 A1552VC_RS02395 WP_001235051.1 487553..490126(+) (clpC) [Vibrio cholerae strain A1552]
ATGCGTCTTGACAGATTTACGAGCAAATTTCAGATCGCGATTTCCGATGCCCAGTCATTAGCGCTCGGCCGTGATCATCA
ATATATCGAACCTGTGCACCTGATGGTGGCTCTGCTGGATCAAAACGGCAGCCCGATCCGCCCATTACTCACCATGCTTA
ATGTGGATGTGATGCAACTGCGCTCCAAACTTGGCGAAATGCTCGATCGTTTACCCAAAGTCAGTGGTATTGGTGGTGAT
GTACAGCTCTCTTCGGCGCTTGGCTCGCTGTTTAATCTGTGTGATAAGGTTGCGCAAAAGCGTCAAGATGCCTACATCTC
CTCTGAAATCTATCTACTTGCTGCGATTGAGGACAAAGGGCCACTGGGTCACTTACTCAAAGAGTTTGGACTGACCGAGA
AAAAAGTCTCTGAAGCAATAGAGAAGATTCGTGGTGGACAAAAGGTTAATGACCCGAATGCGGAAGAGCTGCGTCAAGCG
TTGGAAAAATTCACCATCGATCTGACTGAACGCGCTGAGCAGGGCAAACTCGATCCTGTGATCGGTCGTGATGATGAAAT
TCGCCGCACCATTCAAGTGCTGCAACGCCGTACCAAGAACAATCCGGTGATCATCGGTGAACCCGGTGTGGGTAAAACTG
CGATTGTGGAAGGCTTGGCGCAGCGCATCATTAATAATGAAGTACCAGAAGGCCTGCGTGGACGGCGAGTGTTGTCTTTA
GATATGGGCGCGCTAGTGGCAGGGGCGAAATACCGCGGCGAATTTGAAGAGCGCTTGAAATCAGTACTCAATGAGCTAGC
GAAAGAAGAAGGCAATATCATCCTCTTCATTGATGAGCTGCACACCATGGTTGGTGCGGGGAAAGGCGAAGGCTCGATGG
ATGCCGGCAACATGCTCAAACCCGCTTTGGCGCGTGGAGAATTGCACTGTGTCGGCGCAACCACTTTAGATGAGTACCGC
CAATACATCGAAAAAGATCCAGCGTTAGAGCGCCGCTTCCAAAAAGTGTTGGTGGATGAGCCCACGGTGGAAGATACCAT
CGCCATCTTGCGTGGATTGAAAGAGCGTTATGAACTGCATCACCATGTCGAAATCACAGATCCAGCGATTGTGGCGGCAG
CGAGCCTATCGCATCGCTATATTTCCGATCGCCAGTTGCCTGATAAAGCGATCGATTTGATCGATGAAGCGGCTTCAAGC
ATCCGGATGCAGATTGACTCCAAACCAGAAGCTCTGGATAAGCTTGAGCGCAAAATCATCCAACTGAAAATCGAGCAGCA
AGCGCTCTCTAATGAGCACGATGAAGCCAGTGAAAAACGCTTGGCGATCTTAAATGAAGAGCTGCAAGAGAAAGAGCGTG
ATTACGCGGAGTTGGAAGAAGTGTGGAAAGCTGAAAAGGCGGCACTCTCCGGCACGCAACATATTAAAGCGGCACTTGAA
CAAGCGCGGATGGATCTGGAAGTCGCTCGCCGTGCGGGGGATTTGAACCGCATGTCAGAGCTGCAATATGGTCGCATTCC
AGAGCTAGAAAAGCAGCTTGATCTGGCTGCGCAAGCCGAAATGCAGGAAATGACTCTGCTACGTAATAAAGTGACGGATG
CAGAAATTGCCGAAGTGCTTTCAAAACAGACTGGCATTCCAGTATCAAAAATGCTCGAAGCTGAGAAAGAAAAGTTGCTG
CGCATGGAAGACGTGCTGCATAAACGCGTGATTGGTCAAAAAGAAGCGGTGGAAGTGGTCGCGAATGCGATCCGCCGCAG
TCGCGCAGGGCTTTCTGATCCAAATCGTCCGATTGGCTCCTTCTTATTCTTGGGGCCAACAGGGGTCGGTAAAACCGAGC
TGTGTAAAACCTTGGCTAACTTCCTGTTTGACAGTGAAGATGCCATGGTACGTGTGGATATGTCGGAATTTATGGAGAAA
CACTCGGTTGCTCGTTTAGTCGGTGCGCCTCCAGGTTATGTCGGCTATGAAGAAGGTGGCTACTTAACGGAAGCTGTACG
CCGTAAACCTTACTCGGTGATTTTGCTCGATGAAGTGGAAAAGGCGCACCCAGATGTCTTCAATATTCTGCTGCAAGTCT
TGGATGATGGCCGCTTGACGGACGGACAAGGGCGCACGGTCGATTTTCGAAATACCGTTGTGATCATGACCTCCAACTTG
GGTTCAAGCCGTATCCAAGAAAATTTTGCAAGGTTGGATTATCAAGGTATCAAAGAACAAGTGATGGACGTAGTCAGCAA
ACACTTCCGTCCTGAGTTCTTGAACCGAGTGGATGAAAGTGTGGTATTCCACCCATTAGGACAAGAGCATATCAAGTCGA
TCGCTTCTATTCAGTTGGCCCGCCTACGTCAACGTTTGGCAGAGCGAGATTACCAACTAGAGGTTGATGATGAGGCGCTG
GATCTGATTGCTCATGTCGGCTTCGATCCGGTTTATGGTGCTCGTCCACTGAAACGCGCGATTCAACAAAATGTGGAAAA
CCCACTGGCCAAATCGATTCTGGCTGGTAAGTTCCTGCCTGGTTCACCTATTTTACTATCGGTAAAAGACGGGAATATTT
TCGCAAGCCAGTAG

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (596-759)

• AAA lid domain (AAA_lid_9) (342-442)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-843)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-335)

3D structure

• AlphaFold DB: Q9KU18

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.569	100	0.48
clpC	Lactococcus lactis subsp. cremoris KW2	47.33	80.863	0.383