Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   DB248_RS04145 Genome accession   NZ_CP028841
Coordinates   778834..779310 (+) Length   158 a.a.
NCBI ID   WP_010922230.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain CCUG 4207     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 773834..784310
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DB248_RS04120 (DB248_04120) - 773875..774663 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  DB248_RS04125 (DB248_04125) - 774703..775809 (+) 1107 WP_029713989.1 FAD-binding oxidoreductase -
  DB248_RS04130 (DB248_04130) rfbA 775867..776736 (+) 870 WP_010922195.1 glucose-1-phosphate thymidylyltransferase RfbA -
  DB248_RS04135 (DB248_04135) - 776736..777329 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  DB248_RS04140 (DB248_04140) rfbB 777573..778613 (+) 1041 WP_010922196.1 dTDP-glucose 4,6-dehydratase -
  DB248_RS04145 (DB248_04145) mutX 778834..779310 (+) 477 WP_010922230.1 8-oxo-dGTP diphosphatase Machinery gene
  DB248_RS04150 (DB248_04150) - 779368..780549 (+) 1182 WP_002990002.1 AI-2E family transporter -
  DB248_RS04155 (DB248_04155) - 780539..781786 (+) 1248 WP_010922231.1 tetratricopeptide repeat protein -
  DB248_RS04160 (DB248_04160) fbp54 781845..783497 (-) 1653 WP_010922232.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18452.64 Da        Isoelectric Point: 4.3268

>NTDB_id=248573 DB248_RS04145 WP_010922230.1 778834..779310(+) (mutX) [Streptococcus pyogenes strain CCUG 4207]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRSFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=248573 DB248_RS04145 WP_010922230.1 778834..779310(+) (mutX) [Streptococcus pyogenes strain CCUG 4207]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTTCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

69.62

100

0.696