Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   CO686_RS08865 Genome accession   NZ_CP023507
Coordinates   1807578..1810010 (-) Length   810 a.a.
NCBI ID   WP_001109664.1    Uniprot ID   A0AAW7W6I5
Organism   Streptococcus oralis strain FDAARGOS_367     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1802578..1815010
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO686_RS08840 (CO686_08840) - 1803559..1804242 (-) 684 WP_000730903.1 hypothetical protein -
  CO686_RS08845 (CO686_08845) - 1804510..1804740 (+) 231 WP_000933126.1 hypothetical protein -
  CO686_RS08850 (CO686_08850) - 1804808..1805581 (-) 774 WP_000763403.1 NUDIX hydrolase -
  CO686_RS08855 (CO686_08855) pnuC 1805583..1806362 (-) 780 WP_049479311.1 nicotinamide riboside transporter PnuC -
  CO686_RS08860 (CO686_08860) - 1806372..1807430 (-) 1059 WP_000730564.1 AAA family ATPase -
  CO686_RS08865 (CO686_08865) clpC 1807578..1810010 (-) 2433 WP_001109664.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  CO686_RS08870 (CO686_08870) - 1810012..1810470 (-) 459 WP_001211252.1 CtsR family transcriptional regulator -
  CO686_RS08875 (CO686_08875) - 1810589..1811317 (-) 729 WP_049501307.1 ABC transporter ATP-binding protein -
  CO686_RS08880 (CO686_08880) - 1811317..1812324 (-) 1008 WP_049501306.1 ABC transporter substrate-binding protein -
  CO686_RS08885 (CO686_08885) - 1812361..1813119 (-) 759 WP_161800219.1 ABC transporter permease -
  CO686_RS08890 (CO686_08890) - 1813082..1813372 (-) 291 WP_002880743.1 thiamine-binding protein -

Sequence

Protein


Download         Length: 810 a.a.        Molecular weight: 90374.20 Da        Isoelectric Point: 5.9333

>NTDB_id=247885 CO686_RS08865 WP_001109664.1 1807578..1810010(-) (clpC) [Streptococcus oralis strain FDAARGOS_367]
MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEVALELTETDYSQDETFTELPF
SHRLEVLFAEAEYVASVVHTKVLGTEHVLYAILHDGNALATRILERAGFSYEDQKDQVRIAALRRNLEERAGWTREDLKA
LRQRHRTVADKQNSMANMMGMPQNPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
TALALGLAQRIASGDVPAEMGKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGKVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSLADSMTILQGLKATYEKHHRVQITDEAVET
AVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVRMDESDLSPADKALMDGKWKQAGQLIAKEQELPVYKDLVTESDI
LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAK
ALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDD
GVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDIRFDQENMEKRIFEELKKAYRPEFINRIDEKLVFHSLDS
EHMQEIVKIMVKPLIASLAEKGIDLKLQASALKLLASQGYDPEMGARPLRRTLQTEVEDKLAELLLKGELVAGKTLKIGV
KAGQLKFDIA

Nucleotide


Download         Length: 2433 bp        

>NTDB_id=247885 CO686_RS08865 WP_001109664.1 1807578..1810010(-) (clpC) [Streptococcus oralis strain FDAARGOS_367]
ATGAATTATTCAAAAGCGTTGAATGAATGTATCGAAAGTGCCTACATGGTTGCGGGCCATTTTGGAGCTCGATATCTAGA
GTCTTGGCATTTGTTAATTGCCATGTCCAATCACAGTTACAGTGTGGCAGGTGCGACTCTAAATGATTATCCTTATGAAA
TGGACCGTTTAGAAGAGGTTGCGTTAGAACTGACTGAAACGGACTATAGCCAAGACGAAACCTTTACGGAATTGCCTTTT
TCCCATCGTTTGGAGGTTCTCTTTGCAGAAGCAGAGTATGTGGCCTCAGTGGTCCATACTAAGGTGCTAGGGACAGAGCA
TGTCCTCTATGCGATTTTGCATGATGGCAATGCCTTGGCAACTCGTATCTTGGAGAGAGCAGGCTTTTCTTATGAAGACC
AGAAAGATCAGGTCAGAATTGCTGCTCTTCGTCGCAATCTAGAAGAGCGTGCTGGATGGACAAGAGAAGACCTTAAGGCA
TTGCGTCAGCGCCACCGTACCGTGGCAGATAAGCAAAATTCCATGGCCAATATGATGGGCATGCCTCAGAATCCAAGTGG
CGGTCTAGAGGACTACACGCATGACCTGACAGAGCAAGCGCGCTCTGGCAAGTTAGAGCCAGTTATCGGTCGTGACAAGG
AAATCTCACGTATGATTCAGATTTTGAGTCGGAAGACCAAGAACAATCCTGTCTTGGTTGGAGATGCTGGTGTCGGGAAA
ACAGCTCTGGCTCTTGGACTTGCCCAGCGTATTGCTAGTGGGGATGTACCTGCGGAAATGGGCAAGATGCGCGTTTTGGA
GCTTGATTTGATGAATGTTGTTGCGGGAACACGTTTCCGTGGAGATTTTGAAGAACGCATGAACAACATTATCAAGGATA
TCGAGGAAGATGGTAAGGTAATCCTCTTTATCGATGAACTCCACACCATCATGGGTTCTGGAAGTGGTATTGACTCTACT
CTGGATGCGGCCAATATCTTGAAGCCAGCCTTGGCTCGTGGAACTTTGAGAACGGTTGGTGCAACCACTCAGGAAGAATA
CCAAAAACACATCGAAAAAGACGCAGCTCTTTCTCGTCGTTTTGCCAAAGTGACCATTGAAGAGCCAAGTTTAGCTGACA
GCATGACCATTTTGCAAGGTTTGAAGGCTACCTATGAGAAACACCACCGTGTGCAAATCACAGATGAAGCTGTCGAAACA
GCTGTTAAGATGGCGCATCGTTACTTGACTAGTCGTCACTTGCCAGACTCTGCTATCGATCTATTGGATGAGGCGGCAGC
AACAGTGCAAAACAAATCCAAGCATGTGAGAATGGACGAATCGGACTTGAGTCCAGCTGACAAGGCCTTGATGGATGGCA
AGTGGAAACAAGCAGGCCAGCTAATCGCAAAAGAACAAGAATTGCCTGTCTATAAAGACTTGGTGACAGAATCCGATATT
TTGACCACCTTGAGTCGCTTGTCAGGTATCCCAGTCCAAAAGCTGACGCAAACAGATGCTAAGAAGTACCTGAACTTGGA
AGCAGAACTGCATAAACGCGTCATCGGACAAGATCAAGCTGTTTCAAGTATTAGCCGTGCCATTCGCCGTAATCAGTCAG
GTATTCGTAGTCACAAGCGTCCGATTGGTTCCTTTATGTTCCTAGGGCCGACAGGAGTCGGTAAGACCGAATTGGCCAAG
GCTCTGGCAGAAGTCCTCTTTGATGACGAATCAGCCCTTATTCGCTTTGATATGAGTGAGTATATGGAGAAATTTGCGGC
TAGCCGTCTCAATGGAGCTCCTCCGGGTTATGTGGGCTACGAAGAAGGTGGGGAGTTGACTGAGAAGGTTCGCAACAAAC
CATACTCCGTTCTTCTATTTGACGAGGTAGAAAAGGCCCACCCAGATATCTTTAATGTTCTCTTGCAGGTTCTGGACGAC
GGCGTCTTGACAGATAGCAAGGGGCGCAAGGTTGATTTTTCAAATACCATTATCATCATGACGTCAAACCTTGGTGCGAC
GGCTCTTCGTGATGACAAGACGGTCGGCTTTGGGGCCAAGGACATTCGTTTTGACCAGGAAAATATGGAAAAACGAATCT
TTGAAGAGTTGAAAAAAGCTTATCGACCAGAGTTTATCAACCGTATTGATGAAAAGTTGGTCTTCCATAGCTTAGATAGC
GAACACATGCAGGAAATTGTCAAGATTATGGTGAAACCATTGATTGCTAGCCTCGCTGAGAAGGGCATCGACTTGAAACT
GCAAGCTTCAGCGTTGAAGTTACTAGCAAGTCAAGGATATGATCCAGAAATGGGAGCTCGCCCACTTCGCAGAACCCTGC
AAACAGAAGTGGAAGACAAGCTAGCAGAACTCCTTCTCAAGGGAGAACTAGTAGCAGGCAAGACCCTCAAGATAGGTGTT
AAAGCTGGTCAATTAAAATTTGATATTGCTTAA

Domains

Predicted by InterproScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(103-133)

AAA domain (Cdc48 subfamily) (AAA_2)

(540-711)

ATPase family associated with various cellular activities (AAA) (AAA)

(231-362)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(718-797)

AAA lid domain (AAA_lid_9)

(371-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus pneumoniae Rx1

96.543

100

0.965
  clpC Streptococcus pneumoniae D39

96.543

100

0.965
  clpC Streptococcus pneumoniae TIGR4

96.543

100

0.965
  clpC Streptococcus mutans UA159

67.282

100

0.675
  clpC Streptococcus thermophilus LMD-9

66.585

100

0.669
  clpC Streptococcus thermophilus LMG 18311

66.462

100

0.668
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

49.879

100

0.509
  clpC Bacillus subtilis subsp. subtilis str. 168

45.488

99.877

0.454
  clpE Streptococcus mutans UA159

48.871

76.543

0.374
  clpC Lactococcus lactis subsp. cremoris KW2

46.805

77.284

0.362

Multiple sequence alignment