Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   CO686_RS00495 Genome accession   NZ_CP023507
Coordinates   87205..88029 (+) Length   274 a.a.
NCBI ID   WP_096753363.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_367     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 82205..93029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO686_RS00460 (CO686_00460) asnA 82295..83287 (+) 993 WP_000747998.1 aspartate--ammonia ligase -
  CO686_RS00465 (CO686_00465) rsmD 83352..83891 (+) 540 WP_096753359.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  CO686_RS00470 (CO686_00470) coaD 83881..84369 (+) 489 WP_096753360.1 pantetheine-phosphate adenylyltransferase -
  CO686_RS00475 (CO686_00475) sepM 84353..85390 (+) 1038 WP_096753361.1 SepM family pheromone-processing serine protease Regulator
  CO686_RS00480 (CO686_00480) - 85446..85676 (+) 231 WP_002892633.1 DUF1146 family protein -
  CO686_RS00485 (CO686_00485) murA 85700..86983 (+) 1284 WP_096753362.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  CO686_RS00490 (CO686_00490) - 86970..87164 (+) 195 WP_000739701.1 DNA-directed RNA polymerase subunit beta -
  CO686_RS00495 (CO686_00495) endA 87205..88029 (+) 825 WP_096753363.1 DNA/RNA non-specific endonuclease Machinery gene
  CO686_RS00500 (CO686_00500) - 88161..89492 (+) 1332 WP_096753364.1 hemolysin family protein -
  CO686_RS00510 (CO686_00510) amiA3 89876..91876 (+) 2001 WP_096753365.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29985.64 Da        Isoelectric Point: 9.9134

>NTDB_id=247837 CO686_RS00495 WP_096753363.1 87205..88029(+) (endA) [Streptococcus oralis strain FDAARGOS_367]
MDKKTRQALIGLLLFLLLAAGSYYIKQMQTAPNTPRTKVSQKKQASEAPSQELAESVLTESIKNQIKGNLEWNGAGAFVV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANAILSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGAYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESLVRKALDQNKRVRYRVTLHYATNEDLVPSASQIE
AKSSDGELEFNVLIPNVQKGIQLDYRTGQVTVTN

Nucleotide


Download         Length: 825 bp        

>NTDB_id=247837 CO686_RS00495 WP_096753363.1 87205..88029(+) (endA) [Streptococcus oralis strain FDAARGOS_367]
ATGGACAAAAAAACAAGACAAGCTCTGATAGGGTTACTTCTATTCTTACTCTTGGCTGCTGGAAGCTACTATATCAAGCA
GATGCAGACAGCGCCAAACACCCCTAGAACCAAGGTTAGTCAGAAAAAACAAGCTTCAGAAGCTCCCAGTCAGGAGCTAG
CTGAAAGTGTCTTAACTGAGTCAATCAAAAACCAAATCAAGGGTAATCTCGAGTGGAATGGAGCAGGGGCCTTTGTTGTC
AATGGCAATAAAACCAATCTAGATGCCAAGGTTTCCAGCAAACCCTATGCGGATAATAAAACAAAGACAGTGGGAAAAGA
AACAGTTCCAACTGTTGCAAATGCCATCTTATCTAAAGCGACTCGGCAGTATAAGAATCGTGAAGAAACAGGCAATGGCT
CAACCTCCTGGACGCCACCAGGATGGCATCAGGTTAAGAATCTAAAGGGAGCCTATACACATGCAGTTGATAGAGGGCAC
CTGCTGGGCTATGCCTTGATAGGTGGTTTGGATGGTTTTGATGCCTCTACCAGCAATCCCAAGAACATTGCAGTCCAGAC
AGCTTGGGCCAATCAGGCTCAGGCTGAAGATTCGACAGGTCAGAACTACTATGAGAGTTTGGTCAGAAAAGCCTTAGACC
AGAATAAGAGAGTCCGTTATCGGGTAACTCTCCACTATGCTACGAATGAGGATCTAGTTCCATCCGCTTCACAAATCGAA
GCCAAGTCTTCAGATGGCGAATTGGAATTCAACGTTCTGATTCCAAATGTTCAAAAGGGTATCCAACTTGATTACCGAAC
AGGTCAGGTCACGGTGACAAACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

89.011

99.635

0.887
  endA Streptococcus pneumoniae D39

89.011

99.635

0.887
  endA Streptococcus pneumoniae R6

89.011

99.635

0.887
  endA Streptococcus pneumoniae TIGR4

89.011

99.635

0.887

Multiple sequence alignment